4LOS

C1s CUB2-CCP1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004252	molecular_function	serine-type endopeptidase activity
A	0006958	biological_process	complement activation, classical pathway

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 401

Chain	Residue
A	GLU211
A	ASP221
A	ASP260
A	THR262
A	GLY263
A	HOH501

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	115
Details	Domain: {"description":"CUB 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00059","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	64
Details	Domain: {"description":"Sushi 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00302","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"23922389","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29311313","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6F1C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6F1H","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"23922389","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29311313","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6F1H","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"29311313","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6F1C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6F1H","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"2141278","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23922389","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---