4LOR

C1s CUB1-EGF-CUB2 in complex with a collagen-like peptide from C1q

Summary for 4LOR

Entry DOI	10.2210/pdb4lor/pdb
Descriptor	Complement C1s subcomponent heavy chain, collagen-like peptide from C1q, CALCIUM ION, ... (6 entities in total)
Functional Keywords	cub domain, egf-like domain, protein collagen complex, c1 complex, hydrolase-protein binding complex, hydrolase/protein binding
Biological source	Homo sapiens (human)
Total number of polymer chains	4
Total formula weight	38942.01
Authors	Wallis, R.,Venkatraman Girija, U.,Moody, P.C.E.,Marshall, J.E. (deposition date: 2013-07-13, release date: 2013-08-07, Last modification date: 2020-07-29)
Primary citation	Venkatraman Girija, U.,Gingras, A.R.,Marshall, J.E.,Panchal, R.,Sheikh, M.A.,Gal, P.,Schwaeble, W.J.,Mitchell, D.A.,Moody, P.C.,Wallis, R. Structural basis of the C1q/C1s interaction and its central role in assembly of the C1 complex of complement activation. Proc.Natl.Acad.Sci.USA, 110:13916-13920, 2013 Cited by PubMed: 23922389 DOI: 10.1073/pnas.1311113110 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation