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PDB: 124 件
4NEH
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BU of 4neh by Molmil
An internal ligand-bound, metastable state of a leukocyte integrin, aXb2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Sen, M, Yuki, K, Springer, T.A.
登録日2013-10-29
公開日2014-01-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7505 Å)
主引用文献An internal ligand-bound, metastable state of a leukocyte integrin, alpha X beta 2.
J.Cell Biol., 203, 2013
7NWL
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BU of 7nwl by Molmil
Cryo-EM structure of human integrin alpha5beta1 (open form) in complex with fibronectin and TS2/16 Fv-clasp
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin alpha-5, ...
著者Schumacher, S, Dedden, D, Vazquez Nunez, R, Matoba, K, Takagi, J, Biertumpfel, C, Mizuno, N.
登録日2021-03-17
公開日2021-06-02
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into integrin alpha 5 beta 1 opening by fibronectin ligand.
Sci Adv, 7, 2021
5NEU
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BU of 5neu by Molmil
Localised Reconstruction of Integrin alpha V beta 6 bound to Foot and Mouth Disease Virus O1 Manisa - Pose B.
分子名称: CALCIUM ION, Capsid protein, Integrin alpha-V, ...
著者Kotecha, A, Stuart, D.
登録日2017-03-11
公開日2017-06-21
最終更新日2018-03-28
実験手法ELECTRON MICROSCOPY (12.3 Å)
主引用文献Rules of engagement between alpha v beta 6 integrin and foot-and-mouth disease virus.
Nat Commun, 8, 2017
5NER
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BU of 5ner by Molmil
Localised reconstruction of alpha v beta 6 bound to Foot and Mouth Disease Virus O PanAsia - Pose A prime.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Integrin alpha-V, ...
著者Kotecha, A, Stuart, D.
登録日2017-03-11
公開日2017-06-21
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (11.5 Å)
主引用文献Rules of engagement between alpha v beta 6 integrin and foot-and-mouth disease virus.
Nat Commun, 8, 2017
5NET
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BU of 5net by Molmil
Localised Reconstruction of Integrin alpha V beta 6 bound to Foot and Mouth Disease Virus O1 Manisa - Pose A.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Integrin alpha-V, ...
著者Kotecha, A, Stuart, D.
登録日2017-03-11
公開日2017-06-21
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (8.6 Å)
主引用文献Rules of engagement between alpha v beta 6 integrin and foot-and-mouth disease virus.
Nat Commun, 8, 2017
5NEM
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BU of 5nem by Molmil
Localised reconstruction of alpha v beta 6 bound to Foot and Mouth Disease Virus O PanAsia - Pose A.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Integrin alpha-V, ...
著者Kotecha, A, Stuart, D.
登録日2017-03-10
公開日2017-06-21
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (10.8 Å)
主引用文献Rules of engagement between alpha v beta 6 integrin and foot-and-mouth disease virus.
Nat Commun, 8, 2017
3K6S
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BU of 3k6s by Molmil
Structure of integrin alphaXbeta2 ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Xie, C, Zhu, J, Chen, X, Mi, L, Nishida, N, Springer, T.A.
登録日2009-10-09
公開日2010-01-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of an integrin with an alphaI domain, complement receptor type 4.
Embo J., 29, 2010
3K72
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BU of 3k72 by Molmil
Structure of integrin alphaX beta2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Xie, C, Zhu, J, Chen, X, Mi, L, Nishida, N, Springer, T.A.
登録日2009-10-11
公開日2010-01-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Structure of an integrin with an alphaI domain, complement receptor type 4.
Embo J., 29, 2010
8T2V
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BU of 8t2v by Molmil
Cryo-EM Structures of Full-length Integrin alphaIIbbeta3 in Native Lipids
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Adair, B, Xiong, J.P, Yeager, M, Arnaout, M.A.
登録日2023-06-06
公開日2023-07-26
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structures of full-length integrin alpha IIb beta 3 in native lipids.
Nat Commun, 14, 2023
8T2U
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BU of 8t2u by Molmil
Cryo-EM Structures of Full-length Integrin alphaIIbbeta3 in Native Lipids complexed with Eptifibatide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Adair, B, Xiong, J.P, Yeager, M, Arnaout, M.A.
登録日2023-06-06
公開日2023-07-26
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Cryo-EM structures of full-length integrin alpha IIb beta 3 in native lipids.
Nat Commun, 14, 2023
3K71
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BU of 3k71 by Molmil
Structure of integrin alphaX beta2 ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Xie, C, Zhu, J, Chen, X, Mi, L, Nishida, N, Springer, T.A.
登録日2009-10-11
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.95 Å)
主引用文献Structure of an integrin with an alphaI domain, complement receptor type 4.
Embo J., 29, 2010
6MSL
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BU of 6msl by Molmil
Integrin AlphaVBeta3 ectodomain bound to EETI-II 2.5D
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cystine Knot Protein 2.5D, ...
著者van Agthoven, J.F, Arnaout, M.A.
登録日2018-10-16
公開日2019-10-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.104 Å)
主引用文献Structural Basis of the Differential Binding of Engineered Knottins to Integrins alpha V beta 3 and alpha 5 beta 1.
Structure, 27, 2019
6MSU
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BU of 6msu by Molmil
Integrin alphaVBeta3 in complex with EETI-II 2.5F
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者van Agthoven, J.F, Arnaout, M.A.
登録日2018-10-18
公開日2019-10-23
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Structural Basis of the Differential Binding of Engineered Knottins to Integrins alpha V beta 3 and alpha 5 beta 1.
Structure, 27, 2019
6NAJ
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BU of 6naj by Molmil
Integrin AlphaVBeta3 ectodomain bound to Hr10 variant of the 10th domain of Fibronectin.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fibronectin, ...
著者van Agthoven, J, Arnaout, M.A.
登録日2018-12-05
公開日2019-12-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure-guided design of pure orthosteric inhibitors of alpha IIb beta 3 that prevent thrombosis but preserve hemostasis.
Nat Commun, 11, 2020
5E6R
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BU of 5e6r by Molmil
Structures of leukocyte integrin aLb2: The aI domain, the headpiece, and the pocket for the internal ligand
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Integrin alpha-L, ...
著者Sen, M, Springer, T.A.
登録日2015-10-10
公開日2016-03-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.901 Å)
主引用文献Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops.
Proc.Natl.Acad.Sci.USA, 113, 2016
5E6U
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BU of 5e6u by Molmil
Structures of leukocyte integrin aLb2: The aI domain, the headpiece, and the pocket for the internal ligand
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
著者Sen, M, Springer, T.A.
登録日2015-10-10
公開日2016-04-06
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops.
Proc.Natl.Acad.Sci.USA, 113, 2016
5E6S
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BU of 5e6s by Molmil
Structures of leukocyte integrin aLB2: The aI domain, the headpiece, and the pocket for the internal ligand
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Integrin alpha-L, ...
著者Springer, T.A, Sen, M.
登録日2015-10-10
公開日2016-03-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops.
Proc.Natl.Acad.Sci.USA, 113, 2016
5ES4
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BU of 5es4 by Molmil
RE-REFINEMENT OF INTEGRIN ALPHAXBETA2 ECTODOMAIN IN THE CLOSED/BENT CONFORMATION
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Sen, M, Springer, T.A.
登録日2015-11-16
公開日2016-03-02
最終更新日2022-03-23
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Leukocyte integrin alpha L beta 2 headpiece structures: The alpha I domain, the pocket for the internal ligand, and concerted movements of its loops.
Proc.Natl.Acad.Sci.USA, 113, 2016
6BXF
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BU of 6bxf by Molmil
Crystal structure of an extended b3 integrin L33
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Chimera protein of Integrin beta-3 and Integrin alpha-L, ...
著者Zhou, D, Zhu, J.
登録日2017-12-18
公開日2018-08-01
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of an extended beta3integrin.
Blood, 132, 2018
6CKB
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BU of 6ckb by Molmil
Crystal structure of an extended beta3 integrin P33
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Chimera protein of Integrin beta-3 and Integrin alpha-L, ...
著者Zhou, D, Zhu, J.
登録日2018-02-27
公開日2018-08-01
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of an extended beta3integrin.
Blood, 132, 2018
6BXB
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BU of 6bxb by Molmil
Crystal structure of an extended b3 integrin P33
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Chimera protein of Integrin beta-3 and Integrin alpha-L, ...
著者Zhou, D, Zhu, J.
登録日2017-12-18
公開日2018-08-01
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structure of an extended beta3integrin.
Blood, 132, 2018
6BXJ
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BU of 6bxj by Molmil
Structure of a single-chain beta3 integrin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Chimera protein of Integrin beta-3 and Integrin alpha-L, MAGNESIUM ION
著者Thinn, A.M.M, Wang, Z, Zhou, D, Zhao, Y, Curtis, B.R, Zhu, J.
登録日2017-12-18
公開日2018-10-03
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.092 Å)
主引用文献Autonomous conformational regulation of beta3integrin and the conformation-dependent property of HPA-1a alloantibodies.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7USL
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BU of 7usl by Molmil
Integrin alphaM/beta2 ectodomain in complex with adenylate cyclase toxin RTX751 and M1F5 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Goldsmith, J.A, McLellan, J.S.
登録日2022-04-25
公開日2022-08-17
最終更新日2022-09-14
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural basis for non-canonical integrin engagement by Bordetella adenylate cyclase toxin.
Cell Rep, 40, 2022
7USM
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BU of 7usm by Molmil
Integrin alphaM/beta2 ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Goldsmith, J.A, McLellan, J.S.
登録日2022-04-25
公開日2022-08-17
最終更新日2022-09-14
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural basis for non-canonical integrin engagement by Bordetella adenylate cyclase toxin.
Cell Rep, 40, 2022

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