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PDB: 151 件
7CVN
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The N-arylsulfonyl-indole-2-carboxamide-based inhibitors against fructose-1,6-bisphosphatase
分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, 4-(3-acetamidophenyl)-N-(4-methoxyphenyl)sulfonyl-7-nitro-1H-indole-2-carboxamide, Fructose-1,6-bisphosphatase 1
著者Wang, X, Zhou, J, Xu, B.
登録日2020-08-26
公開日2020-09-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Design,synthesis,biological evaluation and binding mode analysis of 7-nitro-indole-N-acylarylsulfonamide-based fructose-1,6-bisphosphatase inhibitors
Chinese journal of medicinal chemistry, 30, 2020
7B2O
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BU of 7b2o by Molmil
Crystal structure of Chlamydomonas reinhardtii chloroplastic sedoheptulose-1,7-bisphosphatase
分子名称: FBPase domain-containing protein
著者Le Moigne, T, Lemaire, S.D, Henri, J.
登録日2020-11-27
公開日2021-12-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Crystal structure of Chlamydomonas reinhardtii chloroplastic sedoheptulose-1,7-bisphosphatas
To Be Published
1CNQ
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FRUCTOSE-1,6-BISPHOSPHATASE COMPLEXED WITH FRUCTOSE-6-PHOSPHATE AND ZINC IONS
分子名称: 6-O-phosphono-beta-D-fructofuranose, FRUCTOSE-1,6-BISPHOSPHATASE, PHOSPHATE ION, ...
著者Choe, J, Poland, B.W, Fromm, H, Honzatko, R.
登録日1999-05-21
公開日1999-05-28
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Role of a dynamic loop in cation activation and allosteric regulation of recombinant porcine fructose-1,6-bisphosphatase.
Biochemistry, 37, 1998
3IFC
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Human muscle fructose-1,6-bisphosphatase E69Q mutant in complex with AMP and alpha fructose-6-phosphate
分子名称: 6-O-phosphono-alpha-D-fructofuranose, ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase isozyme 2, ...
著者Kolodziejczyk, R, Zarzycki, M, Jaskolski, M, Dzugaj, A.
登録日2009-07-24
公開日2010-08-11
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structure of E69Q mutant of human muscle fructose-1,6-bisphosphatase
Acta Crystallogr.,Sect.D, 67, 2011
7C9Q
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Crystal structure of Human liver fructose-1,6-bisphoaphatase complex with Mg2+ and AMP
分子名称: ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase 1, MAGNESIUM ION
著者Huang, Y, Li, R, Wan, J.
登録日2020-06-07
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.878 Å)
主引用文献Crystal structure of Human liver fructose-1,6-bisphoaphatase complex with Mg2+ and AMP
To Be Published
7CWE
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Human Fructose-1,6-bisphosphatase 1 in APO R-state
分子名称: Fructose-1,6-bisphosphatase 1, MAGNESIUM ION
著者Chen, Y, Zhang, J, Li, C, Cao, Y.
登録日2020-08-28
公開日2021-09-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Human Fructose-1,6-bisphosphatase 1 in APO R-state
To Be Published
7CVH
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Human Fructose-1,6-bisphosphatase 1 in complex with geranylgeranyl diphosphate
分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase 1, ...
著者Chen, Y, Zhang, J, Li, C, Cao, Y.
登録日2020-08-26
公開日2021-09-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献The structural basis for GGPP activation on the enzymatic activities FBP1
To Be Published
5FBP
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CRYSTAL STRUCTURE OF THE NEUTRAL FORM OF FRUCTOSE-1,6-BISPHOSPHATASE COMPLEXED WITH THE PRODUCT FRUCTOSE 6-PHOSPHATE AT 2.1-ANGSTROMS RESOLUTION
分子名称: 6-O-phosphono-beta-D-fructofuranose, FRUCTOSE 1,6-BISPHOSPHATASE
著者Ke, H, Liang, J.-Y, Zhang, Y, Lipscomb, W.N.
登録日1991-02-11
公開日1992-07-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the neutral form of fructose-1,6-bisphosphatase complexed with the product fructose 6-phosphate at 2.1-A resolution.
Proc.Natl.Acad.Sci.USA, 88, 1991
2Y5K
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Orally active aminopyridines as inhibitors of tetrameric fructose 1,6- bisphosphatase
分子名称: 1-[5-(2-METHOXYETHYL)-4-METHYL-THIOPHEN-2-YL]SULFONYL-3-[4-METHOXY-6-(METHYLCARBAMOYLAMINO)PYRIDIN-2-YL]UREA, FRUCTOSE-1,6-BISPHOSPHATASE 1
著者Ruf, A, Hebeisen, P, Haap, W, Kuhn, B, Mohr, P, Wessel, H.P, Zutter, U, Kirchner, S, Benz, J, Joseph, C, Alvarez-Sanchez, R, Gubler, M, Schott, B, Benardeau, A, Tozzo, E, Kitas, E.
登録日2011-01-14
公開日2011-05-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Orally Active Aminopyridines as Inhibitors of Tetrameric Fructose-1,6-Bisphosphatase.
Bioorg.Med.Chem.Lett., 21, 2011
1D9Q
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OXIDIZED PEA FRUCTOSE-1,6-BISPHOSPHATASE FORM 1
分子名称: FRUCTOSE-1,6-BISPHOSPHATASE
著者Chiadmi, M, Navaza, A, Miginiac-Maslow, M, Jacquot, J.-P, Cherfils, J.
登録日1999-10-29
公開日1999-12-03
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Redox signalling in the chloroplast: structure of oxidized pea fructose-1,6-bisphosphate phosphatase.
EMBO J., 18, 1999
1DBZ
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C153S MUTANT OF PEA FRUCTOSE-1,6-BISPHOSPHATASE
分子名称: FRUCTOSE-1,6-BISPHOSPHATASE
著者Chiadmi, M, Navaza, A, Miginiac-Maslow, M, Jacquot, J.P, Cherfils, J.
登録日1999-11-03
公開日1999-12-03
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Redox signalling in the chloroplast: structure of oxidized pea fructose-1,6-bisphosphate phosphatase.
EMBO J., 18, 1999
1DCU
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BU of 1dcu by Molmil
REDOX SIGNALING IN THE CHLOROPLAST: STRUCTURE OF OXIDIZED PEA FRUCTOSE-1,6-BISPHOSPHATE PHOSPHATASE
分子名称: FRUCTOSE-1,6-BISPHOSPHATASE
著者Chiadmi, M, Navaza, A, Miginiac-Maslow, M, Jacquot, J.P, Cherfils, J.
登録日1999-11-05
公開日1999-12-03
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Redox signalling in the chloroplast: structure of oxidized pea fructose-1,6-bisphosphate phosphatase.
EMBO J., 18, 1999
2Y5L
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orally active aminopyridines as inhibitors of tetrameric fructose 1,6- bisphosphatase
分子名称: FRUCTOSE-1,6-BISPHOSPHATASE 1, N-{[(2Z)-5-bromo-1,3-thiazol-2(3H)-ylidene]carbamoyl}-3-chlorobenzenesulfonamide
著者ruf, a, hebeisen, p, haap, w, kuhn, b, mohr, p, wessel, h.p, zutter, u, kirchner, s, benz, j, joseph, c, alvarez-sanchez, r, gubler, m, schott, b, benardeau, a, tozzo, e, kitas, e.
登録日2011-01-14
公開日2011-05-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Orally Active Aminopyridines as Inhibitors of Tetrameric Fructose-1,6-Bisphosphatase.
Bioorg.Med.Chem.Lett., 21, 2011
2OX3
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BU of 2ox3 by Molmil
R-state, PEP and Fru-6-P-bound, Escherichia coli fructose-1,6-bisphosphatase
分子名称: 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase, PHOSPHOENOLPYRUVATE
著者Hines, J.K, Fromm, H.J, Honzatko, R.B.
登録日2007-02-19
公開日2007-03-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Structures of activated fructose-1,6-bisphosphatase from Escherichia coli. Coordinate regulation of bacterial metabolism and the conservation of the R-state.
J.Biol.Chem., 282, 2007
2FIE
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Structure of human liver FBPase complexed with potent benzoxazole allosteric inhibitors
分子名称: 2,5-DICHLORO-N-[5-METHOXY-7-(6-METHOXYPYRIDIN-3-YL)-1,3-BENZOXAZOL-2-YL]BENZENESULFONAMIDE, Fructose-1,6-bisphosphatase 1
著者Abad-Zapatero, C.
登録日2005-12-29
公開日2006-02-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Benzoxazole benzenesulfonamides as allosteric inhibitors of fructose-1,6-bisphosphatase.
Bioorg.Med.Chem.Lett., 16, 2006
2FIX
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BU of 2fix by Molmil
Structure of human liver FBPase complexed with potent benzoxazole allosteric inhibitiors
分子名称: Fructose-1,6-bisphosphatase 1, N-[7-(3-AMINOPHENYL)-5-METHOXY-1,3-BENZOXAZOL-2-YL]-2,5-DICHLOROBENZENESULFONAMIDE
著者Abad-Zapatero, C.
登録日2005-12-30
公開日2006-02-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Benzoxazole benzenesulfonamides as allosteric inhibitors of fructose-1,6-bisphosphatase.
Bioorg.Med.Chem.Lett., 16, 2006
2Q8M
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T-like Fructose-1,6-bisphosphatase from Escherichia coli with AMP, Glucose 6-phosphate, and Fructose 1,6-bisphosphate bound
分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, 6-O-phosphono-beta-D-glucopyranose, ADENOSINE MONOPHOSPHATE, ...
著者Hines, J.K, Kruesel, C.E, Fromm, H.J, Honzatko, R.B.
登録日2007-06-11
公開日2007-06-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure of Inhibited Fructose-1,6-bisphosphatase from Escherichia coli: DISTINCT ALLOSTERIC INHIBITION SITES FOR AMP AND GLUCOSE 6-PHOSPHATE AND THE CHARACTERIZATION OF A GLUCONEOGENIC SWITCH.
J.Biol.Chem., 282, 2007
2FBP
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STRUCTURE REFINEMENT OF FRUCTOSE-1,6-BISPHOSPHATASE AND ITS FRUCTOSE 2,6-BISPHOSPHATE COMPLEX AT 2.8 ANGSTROMS RESOLUTION
分子名称: FRUCTOSE 1,6-BISPHOSPHATASE
著者Ke, H, Thorpe, C.M, Seaton, B.A, Marcus, F, Lipscomb, W.N.
登録日1990-06-07
公開日1992-04-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure refinement of fructose-1,6-bisphosphatase and its fructose 2,6-bisphosphate complex at 2.8 A resolution.
J.Mol.Biol., 212, 1990
2OWZ
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R-state, citrate and Fru-6-P-bound Escherichia coli fructose-1,6-bisphosphatase
分子名称: 6-O-phosphono-beta-D-fructofuranose, CITRIC ACID, Fructose-1,6-bisphosphatase
著者Hines, J.K, Fromm, H.J, Honzatko, R.B.
登録日2007-02-17
公開日2007-03-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Structures of activated fructose-1,6-bisphosphatase from Escherichia coli. Coordinate regulation of bacterial metabolism and the conservation of the R-state.
J.Biol.Chem., 282, 2007
2F3B
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Mechanism of displacement of a catalytically essential loop from the active site of fructose-1,6-bisphosphatase
分子名称: 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase 1, PHOSPHATE ION, ...
著者Iancu, C.V, Mukund, S, Choe, J.-Y, Fromm, H.J, Honzatko, R.B.
登録日2005-11-20
公開日2006-04-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Mechanism of displacement of a catalytically essential loop from the active site of mammalian fructose-1,6-bisphosphatase.
Biochemistry, 52, 2013
2QVU
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Porcine Liver Fructose-1,6-bisphosphatase cocrystallized with Fru-2,6-P2 and Mg2+, I(T)-state
分子名称: 2,6-di-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase 1, MAGNESIUM ION, ...
著者Hines, J.K, Chen, X, Nix, J.C, Fromm, H.J, Honzatko, R.B.
登録日2007-08-08
公開日2007-10-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structures of mammalian and bacterial fructose-1,6-bisphosphatase reveal the basis for synergism in AMP/fructose 2,6-bisphosphate inhibition
J.Biol.Chem., 282, 2007
2F3D
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Mechanism of displacement of a catalytically essential loop from the active site of fructose-1,6-bisphosphatase
分子名称: 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase 1, ...
著者Iancu, C.V, Mukund, S, Choe, J.-Y, Fromm, H.J, Honzatko, R.B.
登録日2005-11-21
公開日2006-04-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Mechanism of displacement of a catalytically essential loop from the active site of mammalian fructose-1,6-bisphosphatase.
Biochemistry, 52, 2013
2QVR
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E. coli Fructose-1,6-bisphosphatase: Citrate, Fru-2,6-P2, and Mg2+ bound
分子名称: 2,6-di-O-phosphono-beta-D-fructofuranose, CITRIC ACID, Fructose-1,6-bisphosphatase, ...
著者Hines, J.K, Fromm, H.J, Honzatko, R.B.
登録日2007-08-08
公開日2007-10-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Structures of Mammalian and Bacterial Fructose-1,6-bisphosphatase Reveal the Basis for Synergism in AMP/Fructose 2,6-Bisphosphate Inhibition.
J.Biol.Chem., 282, 2007
2FHY
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Structure of human liver FPBase complexed with a novel benzoxazole as allosteric inhibitor
分子名称: 2,5-DICHLORO-N-(5-CHLORO-1,3-BENZOXAZOL-2-YL)BENZENESULFONAMIDE, Fructose-1,6-bisphosphatase 1, MAGNESIUM ION
著者Abad-Zapatero, C.
登録日2005-12-27
公開日2006-02-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Benzoxazole benzenesulfonamides are novel allosteric inhibitors of fructose-1,6-bisphosphatase with a distinct binding mode.
Bioorg.Med.Chem.Lett., 16, 2006
2QVV
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Porcine Liver Fructose-1,6-bisphosphatase cocrystallized with Fru-2,6-P2 and Zn2+, I(T)-state
分子名称: 2,6-di-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase 1, PHOSPHATE ION, ...
著者Hines, J.K, Chen, X, Nix, J.C, Fromm, H.J, Honzatko, R.B.
登録日2007-08-08
公開日2007-10-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Structures of mammalian and bacterial fructose-1,6-bisphosphatase reveal the basis for synergism in AMP/fructose 2,6-bisphosphate inhibition
J.Biol.Chem., 282, 2007

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