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2Y5L

orally active aminopyridines as inhibitors of tetrameric fructose 1,6- bisphosphatase

Summary for 2Y5L
Entry DOI10.2210/pdb2y5l/pdb
Related1FTA 2FHY 2FIE 2FIX 2JJK 2VT5 2WBB 2WBD 2Y5K
DescriptorFRUCTOSE-1,6-BISPHOSPHATASE 1, N-{[(2Z)-5-bromo-1,3-thiazol-2(3H)-ylidene]carbamoyl}-3-chlorobenzenesulfonamide (3 entities in total)
Functional Keywordshydrolase
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains8
Total formula weight298048.69
Authors
Primary citationHebeisen, P.,Haap, W.,Kuhn, B.,Mohr, P.,Wessel, H.P.,Zutter, U.,Kirchner, S.,Ruf, A.,Benz, J.,Joseph, C.,Alvarez-Sanchez, R.,Gubler, M.,Schott, B.,Benardeau, A.,Tozzo, E.,Kitas, E.
Orally Active Aminopyridines as Inhibitors of Tetrameric Fructose-1,6-Bisphosphatase.
Bioorg.Med.Chem.Lett., 21:3237-, 2011
Cited by
PubMed: 21550236
DOI: 10.1016/J.BMCL.2011.04.044
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

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