3IFC

Human muscle fructose-1,6-bisphosphatase E69Q mutant in complex with AMP and alpha fructose-6-phosphate

Summary for 3IFC

Entry DOI	10.2210/pdb3ifc/pdb
Related	1eyj 1eyk 3ifa
Descriptor	Fructose-1,6-bisphosphatase isozyme 2, ADENOSINE MONOPHOSPHATE, 6-O-phosphono-alpha-D-fructofuranose, ... (6 entities in total)
Functional Keywords	gluconeogenesis, glyconeogenesis, muscle fructose-1, 6-bisphosphatase, protein engineering, calcium inhibition, allosteric enzyme, carbohydrate metabolism, hydrolase, magnesium, metal-binding, phosphoprotein
Biological source	Homo sapiens (human)
Cellular location	Cell junction : O00757
Total number of polymer chains	4
Total formula weight	150510.20
Authors	Kolodziejczyk, R.,Zarzycki, M.,Jaskolski, M.,Dzugaj, A. (deposition date: 2009-07-24, release date: 2010-08-11, Last modification date: 2023-11-01)
Primary citation	Zarzycki, M.,Kolodziejczyk, R.,Maciaszczyk-Dziubinska, E.,Wysocki, R.,Jaskolski, M.,Dzugaj, A. Structure of E69Q mutant of human muscle fructose-1,6-bisphosphatase Acta Crystallogr.,Sect.D, 67:1028-1034, 2011 Cited by PubMed: 22120740 DOI: 10.1107/S090744491104385X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.97 Å)

Structure validation