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PDB: 113 件
1BNC
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THREE-DIMENSIONAL STRUCTURE OF THE BIOTIN CARBOXYLASE SUBUNIT OF ACETYL-COA CARBOXYLASE
分子名称: BIOTIN CARBOXYLASE, PHOSPHATE ION
著者Waldrop, G, Rayment, I, Holden, H.M.
登録日1994-07-06
公開日1995-08-30
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Three-dimensional structure of the biotin carboxylase subunit of acetyl-CoA carboxylase.
Biochemistry, 33, 1994
5I6I
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Crystal structure of a dBCCP-variant of Chaetomium thermophilum acetyl-CoA carboxylase
分子名称: Acetyl-CoA carboxylase-like protein,Acetyl-CoA carboxylase-like protein,Acetyl-CoA carboxylase-like protein
著者Hunkeler, M, Stuttfeld, E, Hagmann, A, Imseng, S, Maier, T.
登録日2016-02-16
公開日2016-04-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (8.4 Å)
主引用文献The dynamic organization of fungal acetyl-CoA carboxylase.
Nat Commun, 7, 2016
5I8I
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Crystal Structure of the K. lactis Urea Amidolyase
分子名称: Urea Amidolyase
著者Zhao, J, Xiang, S.
登録日2016-02-19
公開日2017-04-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (6.5 Å)
主引用文献Structure and function of urea amidolyase.
Biosci. Rep., 38, 2018
6OJH
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Crystal Structure of Haemophilus Influenzae Biotin Carboxylase Complexed with (R)-7-(3-aminopyrrolidin-1-yl)-6-(naphthalen-1-yl)pyrido[2,3-d]pyrimidin-2-amine
分子名称: 7-[(3R)-3-aminopyrrolidin-1-yl]-6-(naphthalen-1-yl)pyrido[2,3-d]pyrimidin-2-amine, ACETATE ION, Biotin carboxylase, ...
著者Andrews, L.D, Kane, T.R, Dozzo, P, Haglund, C.M, Hilderbrandt, D.J, Linsell, M.S, Machajewski, T, McEnroe, G, Serio, A.W, Wlasichuk, K.B, Neau, D.B, Pakhomova, S, Waldrop, G.L, Sharp, M, Pogliano, J, Cirz, R, Cohen, F.
登録日2019-04-11
公開日2020-02-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal Structure of Haemophilus Influenzae Biotin Carboxylase Complexed with (R)-7-(3-aminopyrrolidin-1-yl)-6-(naphthalen-1-yl)pyrido[2,3-d]pyrimidin-2-amine
To Be Published
6OI8
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Crystal Structure of Haemophilus Influenzae Biotin Carboxylase Complexed with 7-((1R,5S,6s)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl)-6-(2-chloro-6-(pyridin-3-yl)phenyl)pyrido[2,3-d]pyrimidin-2-amine
分子名称: 1,2-ETHANEDIOL, 7-[(1R,5S,6s)-6-amino-3-azabicyclo[3.1.0]hexan-3-yl]-6-[2-chloro-6-(pyridin-3-yl)phenyl]pyrido[2,3-d]pyrimidin-2-amine, Biotin carboxylase
著者Andrews, L.D, Kane, T.R, Dozzo, P, Haglund, C.M, Hilderbrandt, D.J, Linsell, M.S, Machajewski, T, McEnroe, G, Serio, A.W, Wlasichuk, K.B, Neau, D.B, Pakhomova, S, Waldrop, G.L, Sharp, M, Pogliano, J, Cirz, R, Cohen, F.
登録日2019-04-09
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Optimization and Mechanistic Characterization of Pyridopyrimidine Inhibitors of Bacterial Biotin Carboxylase.
J.Med.Chem., 62, 2019
6OI9
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Crystal Structure of E. coli Biotin Carboxylase Complexed with 7-[3-(aminomethyl)pyrrolidin-1-yl]-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-2-amine
分子名称: 1,2-ETHANEDIOL, 7-[(3S)-3-(aminomethyl)pyrrolidin-1-yl]-6-(2,6-dichlorophenyl)pyrido[2,3-d]pyrimidin-2-amine, Biotin carboxylase
著者Andrews, L.D, Kane, T.R, Dozzo, P, Haglund, C.M, Hilderbrandt, D.J, Linsell, M.S, Machajewski, T, McEnroe, G, Serio, A.W, Wlasichuk, K.B, Neau, D.B, Pakhomova, S, Waldrop, G.L, Sharp, M, Pogliano, J, Cirz, R, Cohen, F.
登録日2019-04-09
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Optimization and Mechanistic Characterization of Pyridopyrimidine Inhibitors of Bacterial Biotin Carboxylase.
J.Med.Chem., 62, 2019
7KC7
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Biotin Carboxylase domain of Thermophilic 2-Oxoglutarate Carboxylase bound to ADP without Magnesium with disordered phosphate tail
分子名称: 2-oxoglutarate carboxylase small subunit, ADENOSINE-5'-DIPHOSPHATE, PHOSPHATE ION
著者Buhrman, G.K, Rose, R.B, Enriquez, P, Truong, V.
登録日2020-10-05
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure, Function, and Thermal Adaptation of the Biotin Carboxylase Domain Dimer from Hydrogenobacter thermophilus 2-Oxoglutarate Carboxylase.
Biochemistry, 60, 2021
7KCT
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Crystal Structure of the Hydrogenobacter thermophilus 2-Oxoglutarate Carboxylase (OGC) Biotin Carboxylase (BC) Domain Dimer in Complex with Adenosine 5'-Diphosphate Magnesium Salt (MgADP), Adenosine 5'-Diphosphate (ADP, and Bicarbonate Anion (Hydrogen Carbonate/HCO3-)
分子名称: 2-oxoglutarate carboxylase small subunit, ADENOSINE-5'-DIPHOSPHATE, BICARBONATE ION, ...
著者Buhrman, G.K, Rose, R.B, Enriquez, P, Truong, V.
登録日2020-10-07
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Structure, Function, and Thermal Adaptation of the Biotin Carboxylase Domain Dimer from Hydrogenobacter thermophilus 2-Oxoglutarate Carboxylase.
Biochemistry, 60, 2021
1W96
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Crystal Structure of Biotin Carboxylase Domain of Acetyl-coenzyme A Carboxylase from Saccharomyces cerevisiae in Complex with Soraphen A
分子名称: ACETYL-COENZYME A CARBOXYLASE, SORAPHEN A
著者Shen, Y, Volrath, S.L, Weatherly, S.C, Elich, T.D, Tong, L.
登録日2004-10-06
公開日2005-01-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A Mechanism for the Potent Inhibition of Eukaryotic Acetyl-Coenzyme a Carboxylase by Soraphen A, a Macrocyclic Polyketide Natural Product
Mol.Cell, 16, 2004
1W93
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Crystal Structure of Biotin Carboxylase Domain of Acetyl-Coenzyme A Carboxylase from Saccharomyces cerevisiae
分子名称: ACETYL-COENZYME A CARBOXYLASE
著者Shen, Y, Volrath, S.L, Weatherly, S.C, Elich, T.D, Tong, L.
登録日2004-10-05
公開日2005-01-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A Mechanism for the Potent Inhibition of Eukaryotic Acetyl-Coenzyme a Carboxylase by Soraphen A, a Macrocyclic Polyketide Natural Product
Mol.Cell, 16, 2004
7KBL
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Biotin Carboxylase domain of Thermophilic 2-Oxoglutarate Carboxylase bound to Bicarbonate
分子名称: 2-oxoglutarate carboxylase small subunit, BICARBONATE ION
著者Buhrman, G.K, Rose, R.B, Enriquez, P, Truong, V.
登録日2020-10-02
公開日2021-01-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure, Function, and Thermal Adaptation of the Biotin Carboxylase Domain Dimer from Hydrogenobacter thermophilus 2-Oxoglutarate Carboxylase.
Biochemistry, 60, 2021
1DV2
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BU of 1dv2 by Molmil
The structure of biotin carboxylase, mutant E288K, complexed with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, BIOTIN CARBOXYLASE
著者Thoden, J.B, Blanchard, C.Z, Holden, H.M, Waldrop, G.L.
登録日2000-01-19
公開日2000-06-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Movement of the biotin carboxylase B-domain as a result of ATP binding.
J.Biol.Chem., 275, 2000
1DV1
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STRUCTURE OF BIOTIN CARBOXYLASE (APO)
分子名称: BIOTIN CARBOXYLASE, PHOSPHATE ION
著者Thoden, J.B, Blanchard, C.Z, Holden, H.M, Waldrop, G.L.
登録日2000-01-19
公開日2000-06-09
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Movement of the biotin carboxylase B-domain as a result of ATP binding.
J.Biol.Chem., 275, 2000
8SGZ
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Leishmania tarentolae propionyl-CoA carboxylase (alpha-6-beta-6)
分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-coa carboxylase beta chain, putative, ...
著者Lee, J.K.J, Liu, Y.T, Hu, J.J, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H.
登録日2023-04-13
公開日2023-05-17
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献CryoEM reveals oligomeric isomers of a multienzyme complex and assembly mechanics.
J Struct Biol X, 7, 2023
8SGX
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Leishmania tarentolae propionyl-CoA carboxylase (alpha-4-beta-6)
分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-coa carboxylase beta chain, putative, ...
著者Lee, J.K.J, Liu, Y.T, Hu, J.J, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H.
登録日2023-04-13
公開日2023-05-17
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (10.3 Å)
主引用文献CryoEM reveals oligomeric isomers of a multienzyme complex and assembly mechanics.
J Struct Biol X, 7, 2023
8SGY
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Leishmania tarentolae propionyl-CoA carboxylase (alpha-5-beta-6)
分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-coa carboxylase beta chain, putative, ...
著者Lee, J.K.J, Liu, Y.T, Hu, J.J, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H.
登録日2023-04-13
公開日2023-05-17
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (8.62 Å)
主引用文献CryoEM reveals oligomeric isomers of a multienzyme complex and assembly mechanics.
J Struct Biol X, 7, 2023
8RTH
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BU of 8rth by Molmil
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase
分子名称: 3-methylcrotonyl-CoA carboxylase, putative, 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ...
著者Ruiz, F.M, Plaza-Pegueroles, A, Fernandez-Tornero, C.
登録日2024-01-26
公開日2024-04-17
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.37 Å)
主引用文献The cryo-EM structure of trypanosome 3-methylcrotonyl-CoA carboxylase provides mechanistic and dynamic insights into its enzymatic function.
Structure, 32, 2024
2QF7
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Crystal structure of a complete multifunctional pyruvate carboxylase from Rhizobium etli
分子名称: CHLORIDE ION, COENZYME A, FORMIC ACID, ...
著者St Maurice, M, Surinya, K.H, Rayment, I.
登録日2007-06-27
公開日2007-09-04
最終更新日2012-02-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Domain architecture of pyruvate carboxylase, a biotin-dependent multifunctional enzyme
Science, 317, 2007
2GPW
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Crystal Structure of the Biotin Carboxylase Subunit, F363A Mutant, of Acetyl-CoA Carboxylase from Escherichia coli.
分子名称: Biotin carboxylase
著者Shen, Y, Chou, C.Y, Chang, G.G, Tong, L.
登録日2006-04-18
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Is dimerization required for the catalytic activity of bacterial biotin carboxylase?
Mol.Cell, 22, 2006
2GPS
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Crystal Structure of the Biotin Carboxylase Subunit, E23R mutant, of Acetyl-CoA Carboxylase from Escherichia coli.
分子名称: Biotin carboxylase
著者Shen, Y, Chou, C.Y, Chang, G.G, Tong, L.
登録日2006-04-18
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Is dimerization required for the catalytic activity of bacterial biotin carboxylase?
Mol.Cell, 22, 2006
2V59
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 2
分子名称: 6-(2,6-DIMETHOXYPHENYL)PYRIDO[2,3-D]PYRIMIDINE-2,7-DIAMINE, BIOTIN CARBOXYLASE
著者Mochalkin, I, Miller, J.R.
登録日2008-10-02
公開日2009-01-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore.
Proc.Natl.Acad.Sci.USA, 106, 2009
2V58
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 1
分子名称: 6-(2,6-dibromophenyl)pyrido[2,3-d]pyrimidine-2,7-diamine, BIOTIN CARBOXYLASE, CHLORIDE ION
著者Mochalkin, I, Miller, J.R.
登録日2008-10-02
公開日2009-01-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore.
Proc.Natl.Acad.Sci.USA, 106, 2009
2V5A
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CRYSTAL STRUCTURE OF BIOTIN CARBOXYLASE FROM E.COLI IN COMPLEX WITH POTENT INHIBITOR 3
分子名称: 7-(2,5-dihydropyrrol-1-yl)-6-phenyl-pyrido[6,5-d]pyrimidin-2-amine, BIOTIN CARBOXYLASE, CHLORIDE ION
著者Mochalkin, I, Miller, J.R.
登録日2008-10-02
公開日2009-01-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献A Class of Selective Antibacterials Derived from a Protein Kinase Inhibitor Pharmacophore.
Proc.Natl.Acad.Sci.USA, 106, 2009
2HJW
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Crystal Structure of the BC domain of ACC2
分子名称: Acetyl-CoA carboxylase 2
著者Cho, Y.S, Lee, J.I, Shin, D, Kim, H.T, Lee, T.G, Heo, Y.S.
登録日2006-07-02
公開日2007-07-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the biotin carboxylase domain of human acetyl-CoA carboxylase 2.
Proteins, 70, 2008
2DZD
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Crystal structure of the biotin carboxylase domain of pyruvate carboxylase
分子名称: pyruvate carboxylase
著者Kondo, S, Nakajima, Y, Sugio, S, Sueda, S, Islam, M.N, Kondo, H.
登録日2006-09-27
公開日2007-09-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the biotin carboxylase domain of pyruvate carboxylase from Bacillus thermodenitrificans
ACTA CRYSTALLOGR.,SECT.D, 63, 2007

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