3KIJ
 
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6ELW
 | | High resolution structure of selenocysteine containing human GPX4 | | 分子名称: | CHLORIDE ION, Phospholipid hydroperoxide glutathione peroxidase, mitochondrial | | 著者 | Kalms, J, Borchert, A, Kuhn, H, Scheerer, P. | | 登録日 | 2017-09-29 | | 公開日 | 2018-06-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Crystal structure and functional characterization of selenocysteine-containing glutathione peroxidase 4 suggests an alternative mechanism of peroxide reduction.
Biochim. Biophys. Acta, 1863, 2018
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6VPD
 | | Crystal structure of Trgpx in apo form | | 分子名称: | Glutathione peroxidase | | 著者 | Adriani, P.P, De Oliveira, G.S, Paiva, F.C.R, Dias, M.V.B, Chambergo, F.S. | | 登録日 | 2020-02-03 | | 公開日 | 2020-12-16 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.603 Å) | | 主引用文献 | Structural and functional characterization of the glutathione peroxidase-like thioredoxin peroxidase from the fungus Trichoderma reesei.
Int.J.Biol.Macromol., 167, 2020
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5L71
 | | Crystal structure of mouse phospholipid hydroperoxide glutathione peroxidase 4 (GPx4) | | 分子名称: | 1,2-ETHANEDIOL, Phospholipid hydroperoxide glutathione peroxidase, mitochondrial | | 著者 | Janowski, R, Scanu, S, Madl, T, Niessing, D. | | 登録日 | 2016-06-01 | | 公開日 | 2016-10-19 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal and solution structural studies of mouse phospholipid hydroperoxide glutathione peroxidase 4.
Acta Crystallogr.,Sect.F, 72, 2016
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7FC2
 | | Crystal Structure of GPX6 | | 分子名称: | Glutathione peroxidase 6, SULFATE ION | | 著者 | Sun, J. | | 登録日 | 2021-07-13 | | 公開日 | 2022-07-20 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of GPX6
To Be Published
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1GP1
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2OBI
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2WGR
 | | Combining crystallography and molecular dynamics: The case of Schistosoma mansoni phospholipid glutathione peroxidase | | 分子名称: | GLUTATHIONE PEROXIDASE, PYROPHOSPHATE 2- | | 著者 | Dimastrogiovanni, D, Anselmi, M, Miele, A.E, Boumis, G, Angelucci, F, Di Nola, A, Brunori, M, Bellelli, A. | | 登録日 | 2009-04-24 | | 公開日 | 2009-09-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Combining Crystallography and Molecular Dynamics: The Case of Schistosoma Mansoni Phospholipid Glutathione Peroxidase.
Proteins, 78, 2010
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2VUP
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6HN3
 | | wildtype form (apo) of human GPX4 with Se-Cys46 | | 分子名称: | CHLORIDE ION, ETHANOL, GLYCEROL, ... | | 著者 | Hillig, R.C, Moosmayer, D, Hilpmann, A, Hoffmann, J, Schnirch, L, Eaton, J.K, Badock, V, Gradl, S. | | 登録日 | 2018-09-13 | | 公開日 | 2020-04-01 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.01 Å) | | 主引用文献 | Crystal structures of the selenoprotein glutathione peroxidase 4 in its apo form and in complex with the covalently bound inhibitor ML162.
Acta Crystallogr D Struct Biol, 77, 2021
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6HKQ
 | | Human GPX4 in complex with covalent Inhibitor ML162 (S enantiomer) | | 分子名称: | (2~{S})-2-[2-chloranylethanoyl-(3-chloranyl-4-methoxy-phenyl)amino]-~{N}-(2-phenylethyl)-2-thiophen-2-yl-ethanamide, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, ... | | 著者 | Hillig, R.C, Moosmayer, D, Hilpmann, A, Hoffmann, L, Schnirch, L, Eaton, J.K, Badock, V, Gradl, S. | | 登録日 | 2018-09-07 | | 公開日 | 2020-04-01 | | 最終更新日 | 2022-12-07 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Crystal structures of the selenoprotein glutathione peroxidase 4 in its apo form and in complex with the covalently bound inhibitor ML162.
Acta Crystallogr D Struct Biol, 77, 2021
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2P31
 | | Crystal structure of human glutathione peroxidase 7 | | 分子名称: | CHLORIDE ION, Glutathione peroxidase 7 | | 著者 | Kavanagh, K.L, Johansson, C, Papagrigoriou, E, Kochan, G, Umeano, C, Gileadi, O, von Delft, F, Weigelt, J, Arrowsmith, C.H, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2007-03-08 | | 公開日 | 2007-03-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of human glutathione peroxidase 7
To be Published
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2P5R
 | | Crystal structure of the poplar glutathione peroxidase 5 in the oxidized form | | 分子名称: | CALCIUM ION, Glutathione peroxidase 5 | | 著者 | Koh, C.S, Didierjean, C, Navrot, N, Panjikar, S, Mulliert, G, Rouhier, N, Jacquot, J.-P, Aubry, A, Shawkataly, O, Corbier, C. | | 登録日 | 2007-03-16 | | 公開日 | 2007-07-24 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Crystal Structures of a Poplar Thioredoxin Peroxidase that Exhibits the Structure of Glutathione Peroxidases: Insights into Redox-driven Conformational Changes.
J.Mol.Biol., 370, 2007
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2P5Q
 | | Crystal structure of the poplar glutathione peroxidase 5 in the reduced form | | 分子名称: | ACETATE ION, CADMIUM ION, Glutathione peroxidase 5 | | 著者 | Koh, C.S, Didierjean, C, Navrot, N, Panjikar, S, Mulliert, G, Rouhier, N, Jacquot, J.-P, Aubry, A, Shawkataly, O, Corbier, C. | | 登録日 | 2007-03-16 | | 公開日 | 2007-07-24 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structures of a Poplar Thioredoxin Peroxidase that Exhibits the Structure of Glutathione Peroxidases: Insights into Redox-driven Conformational Changes.
J.Mol.Biol., 370, 2007
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5H5Q
 | | Crystal structure of human GPX4 in complex with GXpep-1 | | 分子名称: | GLYCEROL, GXpep-1, Phospholipid hydroperoxide glutathione peroxidase, ... | | 著者 | Sogabe, S, Kadotani, A, Lane, W, Snell, G. | | 登録日 | 2016-11-09 | | 公開日 | 2016-12-07 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Discovery of GPX4 inhibitory peptides from random peptide T7 phage display and subsequent structural analysis
Biochem. Biophys. Res. Commun., 482, 2017
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5H5R
 | | Crystal structure of human GPX4 in complex with GXpep-2 | | 分子名称: | GLYCEROL, GXpep-2, Phospholipid hydroperoxide glutathione peroxidase, ... | | 著者 | Sogabe, S, Kadotani, A, Lane, W, Snell, G. | | 登録日 | 2016-11-09 | | 公開日 | 2016-12-07 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Discovery of GPX4 inhibitory peptides from random peptide T7 phage display and subsequent structural analysis
Biochem. Biophys. Res. Commun., 482, 2017
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5H5S
 | | Crystal structure of human GPX4 in complex with GXpep-3 | | 分子名称: | GLYCEROL, GXpep-3, Phospholipid hydroperoxide glutathione peroxidase, ... | | 著者 | Sogabe, S, Kadotani, A, Lane, W, Snell, G. | | 登録日 | 2016-11-09 | | 公開日 | 2016-12-07 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Discovery of GPX4 inhibitory peptides from random peptide T7 phage display and subsequent structural analysis
Biochem. Biophys. Res. Commun., 482, 2017
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2R37
 | | Crystal structure of human glutathione peroxidase 3 (selenocysteine to glycine mutant) | | 分子名称: | CHLORIDE ION, Glutathione peroxidase 3, SODIUM ION | | 著者 | Pilka, E.S, Guo, K, Gileadi, O, Rojkowa, A, von Delft, F, Pike, A.C.W, Kavanagh, K.L, Johannson, C, Sundstrom, M, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2007-08-29 | | 公開日 | 2007-09-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal structure of human glutathione peroxidase 3 (selenocysteine to glycine mutant).
TO BE PUBLISHED
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2F8A
 | | Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 1 | | 分子名称: | Glutathione peroxidase 1, MALONIC ACID | | 著者 | Kavanagh, K.L, Johansson, C, Smee, C, Gileadi, O, von Delft, F, Weigelt, J, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2005-12-02 | | 公開日 | 2005-12-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 1
To be Published
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2RM5
 | | Glutathione peroxidase-type tryparedoxin peroxidase, oxidized form | | 分子名称: | Glutathione peroxidase-like protein | | 著者 | Melchers, J, Feher, K, Diechtierow, M, Krauth-Siegel, L, Tews, I, Muhle-Goll, C. | | 登録日 | 2007-10-03 | | 公開日 | 2008-07-29 | | 最終更新日 | 2021-11-10 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for a distinct catalytic mechanism in Trypanosoma brucei tryparedoxin peroxidase
J.Biol.Chem., 283, 2008
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2RM6
 | | Glutathione peroxidase-type tryparedoxin peroxidase, reduced form | | 分子名称: | Glutathione peroxidase-like protein | | 著者 | Melchers, J, Feher, K, Diechtierow, M, Krauth-Siegel, L, Muhle-Goll, C. | | 登録日 | 2007-10-09 | | 公開日 | 2008-07-29 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for a distinct catalytic mechanism in Trypanosoma brucei tryparedoxin peroxidase
J.Biol.Chem., 283, 2008
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3CMI
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2HE3
 | | Crystal structure of the selenocysteine to cysteine mutant of human glutathionine peroxidase 2 (GPX2) | | 分子名称: | CHLORIDE ION, Glutathione peroxidase 2 | | 著者 | Johansson, C, Kavanagh, K.L, Rojkova, A, Gileadi, O, von Delft, F, Arrowsmith, C, Weigelt, J, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2006-06-21 | | 公開日 | 2006-07-25 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of the selenocysteine to cysteine mutant of human glutathionine peroxidase 2 (GPX2)
To be Published
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3DWV
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3CYN
 | | The structure of human GPX8 | | 分子名称: | GLYCEROL, Probable glutathione peroxidase 8, SULFATE ION | | 著者 | Kavanagh, K.L, Johansson, C, Yue, W.W, Kochan, G, Pike, A.C.W, Murray, J, Roos, A.K, Filippakopoulos, P, von Delft, F, Arrowsmith, C.H, Wikstrom, M, Edwards, A.M, Bountra, C, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2008-04-25 | | 公開日 | 2008-08-12 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The structure of human GPX8
To be Published
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