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PDB: 424 件

2GMI
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BU of 2gmi by Molmil
Mms2/Ubc13~Ubiquitin
分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 13, Ubiquitin-conjugating enzyme variant MMS2
著者Wolberger, C, Eddins, M.J, Carlile, C.M, Gomez, K.G, Pickart, C.M.
登録日2006-04-06
公開日2006-09-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mms2-Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formation.
Nat.Struct.Mol.Biol., 13, 2006
2GRO
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BU of 2gro by Molmil
Crystal Structure of human RanGAP1-Ubc9-N85Q
分子名称: Ran GTPase-activating protein 1, Ubiquitin-conjugating enzyme E2 I
著者Yunus, A.A, Lima, C.D.
登録日2006-04-24
公開日2006-05-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway.
Nat.Struct.Mol.Biol., 13, 2006
2GRN
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BU of 2grn by Molmil
Crystal Structure of human RanGAP1-Ubc9
分子名称: Ran GTPase-activating protein 1, Ubiquitin-conjugating enzyme E2 I
著者Yunus, A.A, Lima, C.D.
登録日2006-04-24
公開日2006-05-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway.
Nat.Struct.Mol.Biol., 13, 2006
2GRP
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BU of 2grp by Molmil
Crystal Structure of human RanGAP1-Ubc9-Y87A
分子名称: Ran GTPase-activating protein 1, Ubiquitin-conjugating enzyme E2 I
著者Yunus, A.A, Lima, C.D.
登録日2006-04-24
公開日2006-05-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway.
Nat.Struct.Mol.Biol., 13, 2006
2GRQ
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BU of 2grq by Molmil
Crystal Structure of human RanGAP1-Ubc9-D127A
分子名称: Ran GTPase-activating protein 1, Ubiquitin-conjugating enzyme E2 I
著者Yunus, A.A, Lima, C.D.
登録日2006-04-24
公開日2006-05-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway.
Nat.Struct.Mol.Biol., 13, 2006
2LXP
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BU of 2lxp by Molmil
NMR structure of two domains in ubiquitin ligase gp78, RING and G2BR, bound to its conjugating enzyme Ube2g
分子名称: E3 ubiquitin-protein ligase AMFR, Ubiquitin-conjugating enzyme E2 G2, ZINC ION
著者Das, R, Linag, Y, Mariano, J, Li, J, Huang, T, King, A, Weissman, A, Ji, X, Byrd, R.
登録日2012-08-30
公開日2013-08-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine.
Embo J., 32, 2013
5EYA
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BU of 5eya by Molmil
TRIM25 RING domain in complex with Ubc13-Ub conjugate
分子名称: Polyubiquitin-B, Tripartite motif-containing 25 variant, Ubiquitin-conjugating enzyme E2 N, ...
著者Pornillos, O, Sanchez, J.G.
登録日2015-11-24
公開日2016-08-17
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Mechanism of TRIM25 Catalytic Activation in the Antiviral RIG-I Pathway.
Cell Rep, 16, 2016
5FER
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BU of 5fer by Molmil
Complex of TRIM25 RING with UbcH5-Ub
分子名称: E3 ubiquitin/ISG15 ligase TRIM25, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 D1, ...
著者Rittinger, K, Koliopoulos, M.G, Esposito, D.
登録日2015-12-17
公開日2016-05-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Functional role of TRIM E3 ligase oligomerization and regulation of catalytic activity.
Embo J., 35, 2016
5EDV
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BU of 5edv by Molmil
Structure of the HOIP-RBR/UbcH5B~ubiquitin transfer complex
分子名称: E3 ubiquitin-protein ligase RNF31, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 D2, ...
著者Lechtenberg, B.C, Mace, P.D, Sanishvili, R, Riedl, S.J.
登録日2015-10-22
公開日2016-01-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.48 Å)
主引用文献Structure of a HOIP/E2~ubiquitin complex reveals RBR E3 ligase mechanism and regulation.
Nature, 529, 2016
2OXQ
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BU of 2oxq by Molmil
Structure of the UbcH5 :CHIP U-box complex
分子名称: CHLORIDE ION, STIP1 homology and U-Box containing protein 1, Ubiquitin-conjugating enzyme E2D 1
著者Xu, Z, Nix, J.C, Devlin, K.I, Misra, S.
登録日2007-02-20
公開日2008-02-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Interactions between the quality control ubiquitin ligase CHIP and ubiquitin conjugating enzymes.
Bmc Struct.Biol., 8, 2008
2O25
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BU of 2o25 by Molmil
Ubiquitin-Conjugating Enzyme E2-25 kDa Complexed With SUMO-1-Conjugating Enzyme UBC9
分子名称: SUMO-1-conjugating enzyme UBC9, Ubiquitin-conjugating enzyme E2-25 kDa
著者Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2006-11-29
公開日2007-01-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A Novel and Unexpected Complex Between the SUMO-1-Conjugating Enzyme UBC9 and the Ubiquitin-Conjugating Enzyme E2-25 kDa
To be Published
2PX9
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BU of 2px9 by Molmil
The intrinsic affinity between E2 and the Cys domain of E1 in Ubiquitin-like modifications
分子名称: SUMO-activating enzyme subunit 2, SUMO-conjugating enzyme UBC9
著者Wang, J.H, Hu, W.D, Cai, S, Lee, B, Song, J, Chen, Y.
登録日2007-05-14
公開日2007-07-24
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The intrinsic affinity between E2 and the Cys domain of E1 in ubiquitin-like modifications.
Mol.Cell, 27, 2007
5FQ2
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BU of 5fq2 by Molmil
Crystal structure of human SUMO E1 UFD domain in complex with Ubc9 in a P422 space group.
分子名称: SUMO-ACTIVATING ENZYME SUBUNIT 2, SUMO-CONJUGATING ENZYME UBC9
著者Liu, B, Castano, L, Lois, M, Reverter, D.
登録日2015-12-04
公開日2016-11-16
実験手法X-RAY DIFFRACTION (2.201 Å)
主引用文献Crystal Structure of Human Sumo E1 Ufd Domain in Complex with Ubc9.
To be Published
2PWQ
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BU of 2pwq by Molmil
Crystal structure of a putative ubiquitin conjugating enzyme from Plasmodium yoelii
分子名称: Ubiquitin conjugating enzyme
著者Qiu, W, Dong, A, Hassanali, A, Lin, L, Brokx, S, Altamentova, S, Hills, T, Lew, J, Ravichandran, M, Kozieradzki, I, Zhao, Y, Schapira, M, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Structural Genomics Consortium (SGC)
登録日2007-05-11
公開日2007-05-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of a putative ubiquitin conjugating enzyme from Plasmodium yoelii.
To be Published
2NVU
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BU of 2nvu by Molmil
Structure of APPBP1-UBA3~NEDD8-NEDD8-MgATP-Ubc12(C111A), a trapped ubiquitin-like protein activation complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Maltose binding protein/NEDD8-activating enzyme E1 catalytic subunit chimera, ...
著者Huang, D.T, Hunt, H.W, Zhuang, M, Ohi, M.D, Holton, J.M, Schulman, B.A.
登録日2006-11-13
公開日2007-01-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Basis for a ubiquitin-like protein thioester switch toggling E1-E2 affinity.
Nature, 445, 2007
2PE6
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BU of 2pe6 by Molmil
Non-covalent complex between human SUMO-1 and human Ubc9
分子名称: SUMO-conjugating enzyme UBC9, Small ubiquitin-related modifier 1
著者Capili, A.D, Lima, C.D.
登録日2007-04-02
公開日2007-04-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure and Analysis of a Complex between SUMO and Ubc9 Illustrates Features of a Conserved E2-Ubl Interaction.
J.Mol.Biol., 369, 2007
6ZHS
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BU of 6zhs by Molmil
Uba1 bound to two E2 (Ubc13) molecules
分子名称: GLYCEROL, SULFATE ION, Ubiquitin-activating enzyme E1 1, ...
著者Misra, M, Schindelin, H.
登録日2020-06-23
公開日2022-01-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献ATP induced conformational changes facilitate E1-E2 disulfide bridging in the ubiquitin system.
To Be Published
6ZHT
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BU of 6zht by Molmil
Uba1-Ubc13 disulfide mediated complex
分子名称: CHLORIDE ION, GLYCEROL, Ubiquitin-activating enzyme E1 1, ...
著者Schaefer, A, Misra, M, Schindelin, H.
登録日2020-06-23
公開日2022-01-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献ATP induced conformational changes facilitate E1-E2 disulfide bridging in the ubiquitin system.
To Be Published
6ZHU
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BU of 6zhu by Molmil
Yeast Uba1 in complex with Ubc3 and ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ubiquitin-activating enzyme E1 1, ...
著者Misra, M, Schindelin, H.
登録日2020-06-23
公開日2022-01-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.18 Å)
主引用文献ATP induced conformational changes facilitate E1-E2 disulfide bridging in the ubiquitin system
To Be Published
7AI0
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BU of 7ai0 by Molmil
Crystal structure of human MDM2-G443T RING domain homodimer bound to UbcH5B-Ub (Crystal form 1)
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, ...
著者Magnussen, H.M, Huang, D.T.
登録日2020-09-25
公開日2021-01-20
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.559 Å)
主引用文献Identification of a Catalytic Active but Non-Aggregating MDM2 RING Domain Variant.
J.Mol.Biol., 433, 2021
7AI1
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BU of 7ai1 by Molmil
Crystal structure of human MDM2-G443T RING domain homodimer bound to UbcH5B-Ub (Crystal form 2)
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, ...
著者Magnussen, H.M, Huang, D.T.
登録日2020-09-25
公開日2021-01-20
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Identification of a Catalytic Active but Non-Aggregating MDM2 RING Domain Variant.
J.Mol.Biol., 433, 2021
7AHZ
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BU of 7ahz by Molmil
Crystal structure of Western clawed frog MDM2 RING domain homodimer bound to UbcH5B-Ub
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, Polyubiquitin-B, ...
著者Magnussen, H.M, Huang, D.T.
登録日2020-09-25
公開日2021-01-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Identification of a Catalytic Active but Non-Aggregating MDM2 RING Domain Variant.
J.Mol.Biol., 433, 2021
7BXG
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BU of 7bxg by Molmil
MavC-UBE2N-Ub complex
分子名称: MavC, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 N
著者Gao, P, Wang, Y.
登録日2020-04-19
公開日2020-05-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.705 Å)
主引用文献Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors.
Nat Commun, 11, 2020
7BBF
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BU of 7bbf by Molmil
Crystal structure of ubiquitin charged Ube2N (Ube2N~Ub) in complex with Ube2V2
分子名称: Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 2
著者Kiss, L, Neuhaus, D, James, L.C.
登録日2020-12-17
公開日2021-01-27
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献RING domains act as both substrate and enzyme in a catalytic arrangement to drive self-anchored ubiquitination.
Nat Commun, 12, 2021
2C2V
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BU of 2c2v by Molmil
Crystal structure of the CHIP-UBC13-UEV1a complex
分子名称: STIP1 homology and U box-containing protein 1, Ubiquitin-conjugating enzyme E2 N, Ubiquitin-conjugating enzyme E2 variant 1
著者Zhang, M, Roe, S.M, Pearl, L.H.
登録日2005-09-30
公開日2005-11-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Chaperoned ubiquitylation--crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex.
Mol. Cell, 20, 2005

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件を2024-07-10に公開中

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