4LDT
 
 | | The structure of h/ceOTUB1-ubiquitin aldehyde-UBCH5B~Ub | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, Ubiquitin, ... | | 著者 | Wiener, R, DiBello, A.T, Lombardi, P.M, Guzzo, C.M, Zhang, X, Matunis, M.J, Wolberger, C. | | 登録日 | 2013-06-25 | | 公開日 | 2013-08-14 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | | 主引用文献 | E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1.
Nat.Struct.Mol.Biol., 20, 2013
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4MDK
 | | Cdc34-ubiquitin-CC0651 complex | | 分子名称: | 4,5-dideoxy-5-(3',5'-dichlorobiphenyl-4-yl)-4-[(methoxyacetyl)amino]-L-arabinonic acid, Ubiquitin, Ubiquitin-conjugating enzyme E2 R1 | | 著者 | Ceccarelli, D.F, Orlicky, S, Tyers, M, Sicheri, F. | | 登録日 | 2013-08-22 | | 公開日 | 2013-12-11 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.6095 Å) | | 主引用文献 | E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin.
Nat.Chem.Biol., 10, 2014
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6KFP
 | | Crystal structure of MavC ternary complex | | 分子名称: | MavC, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 N | | 著者 | Mu, Y, Wang, Y, Han, Y, Li, D, Feng, Y. | | 登録日 | 2019-07-08 | | 公開日 | 2020-04-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | | 主引用文献 | Structural insights into the mechanism and inhibition of transglutaminase-induced ubiquitination by the Legionella effector MavC.
Nat Commun, 11, 2020
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7UN6
 | | Complex of UBE2O with NAP1L1 | | 分子名称: | (E3-independent) E2 ubiquitin-conjugating enzyme, Nucleosome assembly protein 1-like 1 | | 著者 | Yip, M.C.J, Sedor, S.F, Shao, S. | | 登録日 | 2022-04-09 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Mechanism of client selection by the protein quality-control factor UBE2O.
Nat.Struct.Mol.Biol., 29, 2022
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7UN3
 | | Complex of UBE2O with NAP1L1 and ubiquitylated uL2 | | 分子名称: | Nucleosome assembly protein 1-like 1, Ubiquitin,60S ribosomal protein L8,(E3-independent) E2 ubiquitin-conjugating enzyme fusion | | 著者 | Yip, M.C.J, Sedor, S.F, Shao, S. | | 登録日 | 2022-04-08 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Mechanism of client selection by the protein quality-control factor UBE2O.
Nat.Struct.Mol.Biol., 29, 2022
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7XED
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8BTL
 | | Crystal structure of a complex between the E2 conjugating enzyme UBE2A and the E3 ligase module from UBR4 | | 分子名称: | Ubiquitin conjugating enzyme E2 A, ZINC ION, cDNA FLJ12511 fis, ... | | 著者 | Virdee, S, Mabbitt, P.D, Barnsby-Greer, L. | | 登録日 | 2022-11-29 | | 公開日 | 2023-12-13 | | 最終更新日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | UBE2A and UBE2B are recruited by an atypical E3 ligase module in UBR4.
Nat.Struct.Mol.Biol., 31, 2024
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4DHJ
 | | The structure of a ceOTUB1 ubiquitin aldehyde UBC13~Ub complex | | 分子名称: | Ubiquitin, Ubiquitin aldehyde, Ubiquitin thioesterase otubain-like, ... | | 著者 | Wiener, R, Zhang, X, Wang, T, Wolberger, C. | | 登録日 | 2012-01-27 | | 公開日 | 2012-02-22 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | The mechanism of OTUB1-mediated inhibition of ubiquitination.
Nature, 483, 2012
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6SQO
 | | Crystal structure of human MDM2 RING domain homodimer bound to UbcH5B-Ub | | 分子名称: | CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, NITRATE ION, ... | | 著者 | Magnussen, H.M, Ahmed, S.F, Huang, D.T. | | 登録日 | 2019-09-04 | | 公開日 | 2020-05-06 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | | 主引用文献 | Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain.
Nat Commun, 11, 2020
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5ULH
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4DHI
 | | Structure of C. elegans OTUB1 bound to human UBC13 | | 分子名称: | Ubiquitin thioesterase otubain-like, Ubiquitin-conjugating enzyme E2 N | | 著者 | Wiener, R, Zhang, X, Wang, T, Wolberger, C. | | 登録日 | 2012-01-27 | | 公開日 | 2012-02-22 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The mechanism of OTUB1-mediated inhibition of ubiquitination.
Nature, 483, 2012
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8ATX
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8ATU
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8AUW
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8AUK
 | | Cryo-EM structure of human BIRC6 in complex with HTRA2. | | 分子名称: | Baculoviral IAP repeat-containing protein 6, Serine protease HTRA2, mitochondrial, ... | | 著者 | Ehrmann, J.F, Grabarczyk, D.B, Clausen, T. | | 登録日 | 2022-08-25 | | 公開日 | 2023-02-15 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | | 主引用文献 | Structural basis for regulation of apoptosis and autophagy by the BIRC6/SMAC complex.
Science, 379, 2023
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8ATM
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8ATO
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6SQS
 | | Crystal structure of cat phospho-Ser429 MDM2 RING domain bound to UbcH5B-Ub | | 分子名称: | E3 ubiquitin-protein ligase Mdm2, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 D2, ... | | 著者 | Magnussen, H.M, Ahmed, S.F, Huang, D.T. | | 登録日 | 2019-09-04 | | 公開日 | 2020-05-06 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain.
Nat Commun, 11, 2020
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3E46
 | | Crystal structure of ubiquitin-conjugating enzyme E2-25kDa (Huntington interacting protein 2) M172A mutant | | 分子名称: | CALCIUM ION, Ubiquitin-conjugating enzyme E2-25 kDa | | 著者 | Hughes, R.C, Wilson, R.C, Flatt, J.W, Meehan, E.J, Ng, J.D, Twigg, P.D. | | 登録日 | 2008-08-09 | | 公開日 | 2008-08-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Structure of full-length ubiquitin-conjugating enzyme E2-25K (huntingtin-interacting protein 2).
Acta Crystallogr.,Sect.F, 65, 2009
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7ZJ3
 | | Structure of TRIM2 RING domain in complex with UBE2D1~Ub conjugate | | 分子名称: | Polyubiquitin-C, Tripartite motif-containing protein 2, Ubiquitin-conjugating enzyme E2 D1, ... | | 著者 | Esposito, D, Garza-Garcia, A, Dudley-Fraser, J, Rittinger, K. | | 登録日 | 2022-04-08 | | 公開日 | 2022-11-30 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | | 主引用文献 | Divergent self-association properties of paralogous proteins TRIM2 and TRIM3 regulate their E3 ligase activity.
Nat Commun, 13, 2022
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4BWF
 | | Pex4p-Pex22p disulphide bond mutant | | 分子名称: | 1,2-ETHANEDIOL, PEROXISOME ASSEMBLY PROTEIN 22, UBIQUITIN-CONJUGATING ENZYME E2-21 KDA | | 著者 | Williams, C, van den Berg, M, Stanley, W.A, Wilmanns, M, Distel, B. | | 登録日 | 2013-07-01 | | 公開日 | 2013-07-17 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.23 Å) | | 主引用文献 | A Disulphide Bond in the E2 Enzyme Pex4P Modulates Ubiquitin-Conjugating Activity
Sci.Rep., 3, 2013
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4BVU
 | | Structure of Shigella effector OspG in complex with host UbcH5c- Ubiquitin conjugate | | 分子名称: | PROTEIN KINASE OSPG, UBIQUITIN, UBIQUITIN-CONJUGATING ENZYME E2 D3 | | 著者 | Pruneda, J.N, LeTrong, I, Stenkamp, R.E, Klevit, R.E, Brzovic, P.S. | | 登録日 | 2013-06-28 | | 公開日 | 2014-01-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | E2~Ub Conjugates Regulate the Kinase Activity of Shigella Effector Ospg During Pathogenesis.
Embo J., 33, 2014
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6SQR
 | | Crystal structure of Cat MDM2-S429E RING domain bound to UbcH5B-Ub | | 分子名称: | 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase Mdm2, NITRATE ION, ... | | 著者 | Magnussen, H.M, Ahmed, S.F, Huang, D.T. | | 登録日 | 2019-09-04 | | 公開日 | 2020-05-06 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain.
Nat Commun, 11, 2020
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3FSH
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5TUT
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