8BTL
Crystal structure of a complex between the E2 conjugating enzyme UBE2A and the E3 ligase module from UBR4
Summary for 8BTL
| Entry DOI | 10.2210/pdb8btl/pdb |
| Descriptor | cDNA FLJ12511 fis, clone NT2RM2001727, highly similar to Homo sapiens ubiquitin protein ligase E3 component n-recognin 4 (UBR4), mRNA, Ubiquitin conjugating enzyme E2 A, ZINC ION (3 entities in total) |
| Functional Keywords | e2 conjugating enzyme, e3 ligase, ubiquitin, ligase |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 3 |
| Total formula weight | 87705.49 |
| Authors | Virdee, S.,Mabbitt, P.D.,Barnsby-Greer, L. (deposition date: 2022-11-29, release date: 2023-12-13, Last modification date: 2024-04-17) |
| Primary citation | Barnsby-Greer, L.,Mabbitt, P.D.,Dery, M.A.,Squair, D.R.,Wood, N.T.,Lamoliatte, F.,Lange, S.M.,Virdee, S. UBE2A and UBE2B are recruited by an atypical E3 ligase module in UBR4. Nat.Struct.Mol.Biol., 31:351-363, 2024 Cited by PubMed: 38182926DOI: 10.1038/s41594-023-01192-4 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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