8BTL
Crystal structure of a complex between the E2 conjugating enzyme UBE2A and the E3 ligase module from UBR4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | cDNA FLJ12511 fis, clone NT2RM2001727, highly similar to Homo sapiens ubiquitin protein ligase E3 component n-recognin 4 (UBR4), mRNA | polymer | 459 | 51755.9 | 1 | UniProt (B3KMT2) Pfam (PF13764) UniProt (by SIFTS) (Q5T4S7) In PDB | Homo sapiens (human) | |
| 2 | C, D | Ubiquitin conjugating enzyme E2 A | polymer | 158 | 17942.1 | 2 | UniProt (A0A7N4PN18) Pfam (PF00179) UniProt (by SIFTS) (P49459) In PDB | Homo sapiens (human) | |
| 3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence modifications
A: 4728 - 5183 (UniProt: B3KMT2)
C, D: -3 - 152 (UniProt: A0A7N4PN18)
| PDB | External Database | Details |
|---|---|---|
| Gly 4725 | - | expression tag |
| Pro 4726 | - | expression tag |
| Leu 4727 | - | expression tag |
| Ser 4729 | Leu 363 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gly -5 | - | expression tag |
| His -4 | - | expression tag |
| Met -3 | Val 23 | conflict |
| Ser 0 | Asp 26 | conflict |
| Lys 88 | Cys 114 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 87640.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 87705.5 |
