8AUW
Cryo-EM structure of human BIRC6 in complex with SMAC.
This is a non-PDB format compatible entry.
Summary for 8AUW
Entry DOI | 10.2210/pdb8auw/pdb |
Related | 8ATU 8ATX 8AUK |
EMDB information | 15675 |
Descriptor | Baculoviral IAP repeat-containing protein 6, Diablo IAP-binding mitochondrial protein, ZINC ION (3 entities in total) |
Functional Keywords | e3 ubiquitin ligase, e2/e3 hybrid, inhibitor of apoptosis protein, ligase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 1105723.01 |
Authors | Ehrmann, J.F.,Grabarczyk, D.B.,Clausen, T. (deposition date: 2022-08-25, release date: 2023-02-15, Last modification date: 2023-05-24) |
Primary citation | Ehrmann, J.F.,Grabarczyk, D.B.,Heinke, M.,Deszcz, L.,Kurzbauer, R.,Hudecz, O.,Shulkina, A.,Gogova, R.,Meinhart, A.,Versteeg, G.A.,Clausen, T. Structural basis for regulation of apoptosis and autophagy by the BIRC6/SMAC complex. Science, 379:1117-1123, 2023 Cited by PubMed: 36758105DOI: 10.1126/science.ade8873 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (7.2 Å) |
Structure validation
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