8AUW
Cryo-EM structure of human BIRC6 in complex with SMAC.
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Baculoviral IAP repeat-containing protein 6 | polymer | 4867 | 532009.0 | 2 | UniProt (Q9NR09) Pfam (PF00653) Pfam (PF12356) Pfam (PF00179) | Homo sapiens (human) | BIR repeat-containing ubiquitin-conjugating enzyme,BRUCE,RING-type E3 ubiquitin transferase BIRC6,Ubiquitin-conjugating BIR domain enzyme apollon,APOLLON |
| 2 | C, D (C, D) | Diablo IAP-binding mitochondrial protein | polymer | 184 | 20787.1 | 2 | UniProt (Q9NR28) Pfam (PF09057) | Homo sapiens (human) | Diablo homolog,mitochondrial,Direct IAP-binding protein with low pI,Second mitochondria-derived activator of caspase,Smac |
| 3 | E, F (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
A, B: 1 - 4857 (UniProt: Q9NR09)
| PDB | External Database | Details |
|---|---|---|
| Val 1332 | Leu 1332 | conflict |
| Ser 4858 | - | expression tag |
| Ala 4859 | - | expression tag |
| Trp 4860 | - | expression tag |
| Ser 4861 | - | expression tag |
| His 4862 | - | expression tag |
| Pro 4863 | - | expression tag |
| Gln 4864 | - | expression tag |
| Phe 4865 | - | expression tag |
| Glu 4866 | - | expression tag |
| Lys 4867 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 1105592.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 1105723.0 |
