7ZJ3

Structure of TRIM2 RING domain in complex with UBE2D1~Ub conjugate

Summary for 7ZJ3

Entry DOI	10.2210/pdb7zj3/pdb
Descriptor	Tripartite motif-containing protein 2, Ubiquitin-conjugating enzyme E2 D1, Polyubiquitin-C, ... (5 entities in total)
Functional Keywords	ubiquitin ligase, trim protein, ring ligase, ligase
Biological source	Homo sapiens (human) More
Total number of polymer chains	12
Total formula weight	146643.29
Authors	Esposito, D.,Garza-Garcia, A.,Dudley-Fraser, J.,Rittinger, K. (deposition date: 2022-04-08, release date: 2022-11-30, Last modification date: 2024-01-31)
Primary citation	Esposito, D.,Dudley-Fraser, J.,Garza-Garcia, A.,Rittinger, K. Divergent self-association properties of paralogous proteins TRIM2 and TRIM3 regulate their E3 ligase activity. Nat Commun, 13:7583-7583, 2022 Cited by PubMed: 36481767 DOI: 10.1038/s41467-022-35300-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.53 Å)

Structure validation