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PDB: 119 件

1NNH
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Hypothetical protein from Pyrococcus furiosus Pfu-1801964
分子名称: SODIUM ION, asparaginyl-tRNA synthetase-related peptide
著者Tempel, W, Liu, Z.-J, Schubot, F.D, Shah, A, Arendall III, W.B, Rose, J.P, Richardson, D.C, Richardson, J.S, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2003-01-13
公開日2004-02-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Hypothetical protein from Pyrococcus furiosus Pfu-1801964
To be published
3REU
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Crystal structure of the archaeal asparagine synthetase A complexed with L-Aspartic acid and Adenosine triphosphate
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ASPARTIC ACID, AsnS-like asparaginyl-tRNA synthetase related protein, ...
著者Blaise, M, Frechin, M, Charron, C, Roy, H, Sauter, C, Lorber, B, Olieric, V, Kern, D.
登録日2011-04-05
公開日2011-08-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of the Archaeal Asparagine Synthetase: Interrelation with Aspartyl-tRNA and Asparaginyl-tRNA Synthetases.
J.Mol.Biol., 412, 2011
3G1Z
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Structure of IDP01693/yjeA, a potential t-RNA synthetase from Salmonella typhimurium
分子名称: ADENOSINE MONOPHOSPHATE, CHLORIDE ION, PHOSPHATE ION, ...
著者Singer, A.U, Evdokimova, E, Kudritska, M, Cuff, M.E, Edwards, A.M, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2009-01-30
公開日2009-03-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献PoxA, yjeK, and elongation factor P coordinately modulate virulence and drug resistance in Salmonella enterica.
Mol.Cell, 39, 2010
3REX
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Crystal structure of the archaeal asparagine synthetase A complexed with Adenosine monophosphate
分子名称: ADENOSINE MONOPHOSPHATE, AsnS-like asparaginyl-tRNA synthetase related protein, MAGNESIUM ION
著者Blaise, M, Frechin, M, Charron, C, Roy, H, Sauter, C, Lorber, B, Olieric, V, Kern, D.
登録日2011-04-05
公開日2011-08-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of the Archaeal Asparagine Synthetase: Interrelation with Aspartyl-tRNA and Asparaginyl-tRNA Synthetases.
J.Mol.Biol., 412, 2011
3RL6
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Crystal structure of the archaeal asparagine synthetase A complexed with L-Asparagine and Adenosine monophosphate
分子名称: ADENOSINE MONOPHOSPHATE, ASPARAGINE, Archaeal asparagine synthetase A, ...
著者Blaise, M, Frechin, M, Charron, C, Roy, H, Sauter, C, Lorber, B, Olieric, V, Kern, D.
登録日2011-04-19
公開日2011-08-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the Archaeal Asparagine Synthetase: Interrelation with Aspartyl-tRNA and Asparaginyl-tRNA Synthetases.
J.Mol.Biol., 412, 2011
3A5Y
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Crystal structure of GenX from Escherichia coli in complex with lysyladenylate analog
分子名称: 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE, Putative lysyl-tRNA synthetase
著者Sumida, T, Yanagisawa, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2009-08-17
公開日2010-08-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A paralog of lysyl-tRNA synthetase aminoacylates a conserved lysine residue in translation elongation factor P.
Nat.Struct.Mol.Biol., 17, 2010
3P8Y
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Crystal structure of the archaeal asparagine synthetase A complexed with L-Asparagine
分子名称: ASPARAGINE, AsnS-like asparaginyl-tRNA synthetase related protein
著者Blaise, M, Kern, D.
登録日2010-10-15
公開日2011-08-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of the Archaeal Asparagine Synthetase: Interrelation with Aspartyl-tRNA and Asparaginyl-tRNA Synthetases.
J.Mol.Biol., 412, 2011
3P8T
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Crystal structure of the archaeal asparagine synthetase A
分子名称: AsnS-like asparaginyl-tRNA synthetase related protein
著者Blaise, M, Kern, D.
登録日2010-10-15
公開日2011-08-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Crystal Structure of the Archaeal Asparagine Synthetase: Interrelation with Aspartyl-tRNA and Asparaginyl-tRNA Synthetases.
J.Mol.Biol., 412, 2011
3P8V
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Crystal structure of the archaeal asparagine synthetase A complexed with L-Aspartic acid
分子名称: ASPARTIC ACID, AsnS-like asparaginyl-tRNA synthetase related protein
著者Blaise, M, Kern, D.
登録日2010-10-15
公開日2011-08-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of the Archaeal Asparagine Synthetase: Interrelation with Aspartyl-tRNA and Asparaginyl-tRNA Synthetases.
J.Mol.Biol., 412, 2011
6OD8
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Crystal structure of a putative aspartyl-tRNA synthetase from Leishmania major Friedlin
分子名称: 1,2-ETHANEDIOL, FORMIC ACID, Putative aspartyl-tRNA synthetase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2019-03-26
公開日2019-04-17
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of a putative aspartyl-tRNA synthetase from Leishmania major Friedlin
to be published
4WJ3
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Crystal structure of the asparagine transamidosome from Pseudomonas aeruginosa
分子名称: 76mer-tRNA, Aspartate--tRNA(Asp/Asn) ligase, Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, ...
著者Suzuki, T, Nakamura, A, Kato, K, Tanaka, I, Yao, M.
登録日2014-09-29
公開日2014-12-31
最終更新日2020-02-05
実験手法X-RAY DIFFRACTION (3.705 Å)
主引用文献Structure of the Pseudomonas aeruginosa transamidosome reveals unique aspects of bacterial tRNA-dependent asparagine biosynthesis
Proc.Natl.Acad.Sci.USA, 112, 2015
7ZOG
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Crystal structure of Cryptosporidium parvum -Plasmodium falciparum mutant lysyl tRNA synthetase in complex with inhibitor
分子名称: 8-[[4-[2-[2-[2-[2-[(azanylidene-$l^{4}-azanylidene)amino]ethoxy]ethoxy]ethoxy]ethylcarbamoyl]phenyl]sulfonylamino]-~{N}-(cyclohexylmethyl)-6-fluoranyl-4-oxidanylidene-chromene-2-carboxamide, GLYCEROL, LYSINE, ...
著者Dawson, A, Wyllie, S.
登録日2022-04-25
公開日2022-09-07
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Toolkit of Approaches To Support Target-Focused Drug Discovery for Plasmodium falciparum Lysyl tRNA Synthetase.
Acs Infect Dis., 8, 2022
6SJC
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Structure of T. thermophilus AspRS in Complex with 5'-O-(N-(L-aspartyl)-sulfamoyl)adenosine
分子名称: 5'-O-(L-alpha-aspartylsulfamoyl)adenosine, Aspartate--tRNA(Asp) ligase
著者De Graef, S, Pang, L, Strelkov, S.V, Weeks, S.D.
登録日2019-08-13
公開日2020-01-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Structural Insights into the Binding of Natural Pyrimidine-Based Inhibitors of Class II Aminoacyl-tRNA Synthetases.
Acs Chem.Biol., 15, 2020
1G51
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ASPARTYL TRNA SYNTHETASE FROM THERMUS THERMOPHILUS AT 2.4 A RESOLUTION
分子名称: ADENOSINE MONOPHOSPHATE, ASPARTYL-ADENOSINE-5'-MONOPHOSPHATE, ASPARTYL-TRNA SYNTHETASE, ...
著者Poterzsman, A, Delarue, M, Thierry, J.C, Moras, D.
登録日2000-10-30
公開日2000-12-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Synthesis and recognition of aspartyl-adenylate by Thermus thermophilus aspartyl-tRNA synthetase.
J.Mol.Biol., 244, 1994
4AH6
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Human mitochondrial aspartyl-tRNA synthetase
分子名称: ASPARTATE--TRNA LIGASE, MITOCHONDRIAL
著者Neuenfeldt, A, Sissler, M, Lorber, B, Florentz, C, Sauter, C.
登録日2012-02-03
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Thermodynamic Properties Distinguish Human Mitochondrial Aspartyl-tRNA Synthetase from Bacterial Homolog with Same 3D Architecture
Nucleic Acids Res., 41, 2013
8H53
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Human asparaginyl-tRNA synthetase in complex with asparagine-AMP
分子名称: 4-AMINO-1,4-DIOXOBUTAN-2-AMINIUM ADENOSINE-5'-MONOPHOSPHATE, Asparagine--tRNA ligase, cytoplasmic, ...
著者Park, J.S, Han, B.W.
登録日2022-10-12
公開日2023-10-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase.
Nat Commun, 15, 2024
5ELO
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BU of 5elo by Molmil
Crystal Structure of Lysyl-tRNA Synthetase from Cryptosporidium parvum complexed with L-lysine and cladosporin
分子名称: 1,2-ETHANEDIOL, LYSINE, Lysine--tRNA ligase, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2015-11-04
公開日2016-11-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.
Proc. Natl. Acad. Sci. U.S.A., 2019
3I7F
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Aspartyl tRNA synthetase from Entamoeba histolytica
分子名称: Aspartyl-tRNA synthetase
著者Arakaki, T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日2009-07-08
公開日2009-07-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the aspartyl-tRNA synthetase from Entamoeba histolytica.
Mol.Biochem.Parasitol., 169, 2010
6L4Q
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Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum complexed with L-lysine and Clado-B
分子名称: (3R)-3-[[(3R)-3-methylpiperidin-1-yl]methyl]-6,8-bis(oxidanyl)-3,4-dihydroisochromen-1-one, LYSINE, Lysine--tRNA ligase
著者Babbar, P, Sharma, A, Manickam, Y, Mishra, S, Harlos, K.
登録日2019-10-19
公開日2021-05-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum complexed with L-lysine and Cladosporin inhibitor, Cla-B
Chembiochem, 2021
6L3Y
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Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum complexed with L-lysine and Clado-C
分子名称: (3R)-3-[[(3S)-3-ethylpiperidin-1-yl]methyl]-6,8-bis(oxidanyl)-3,4-dihydroisochromen-1-one, LYSINE, Lysine--tRNA ligase, ...
著者Babbar, P, Sharma, A, Mishra, S, Manickam, Y, Harlos, K.
登録日2019-10-15
公開日2021-05-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum complexed with L-lysine and Cladosporin inhibitor, Cla-B
Chembiochem, 2021
4EX5
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Crystal structure of lysyl-tRNA synthetase LysRS from Burkholderia thailandensis bound to lysine
分子名称: LYSINE, Lysine--tRNA ligase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-04-29
公開日2012-05-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms.
Sci Rep, 7, 2017
7BT5
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Crystal structure of plasmodium LysRS complexing with an antitumor compound
分子名称: LYSINE, Lysine--tRNA ligase, N4-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-N2-(2-propan-2-ylsulfonylphenyl)-1,3,5-triazine-2,4-diamine
著者Zhou, J, Wang, J, Fang, P.
登録日2020-03-31
公開日2020-09-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.493 Å)
主引用文献Inhibition of Plasmodium falciparum Lysyl-tRNA synthetase via an anaplastic lymphoma kinase inhibitor.
Nucleic Acids Res., 48, 2020
4J15
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Crystal structure of human cytosolic aspartyl-tRNA synthetase, a component of multi-tRNA synthetase complex
分子名称: Aspartate--tRNA ligase, cytoplasmic, GLYCEROL
著者Kim, K.R, Park, S.H, Kim, H.S, Kim, B.-G, Kim, D.G, Rhee, K.H, Park, M.S, Kim, H.-J, Kim, S, Han, B.W.
登録日2013-02-01
公開日2013-05-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Crystal structure of human cytosolic aspartyl-tRNA synthetase, a component of multi-tRNA synthetase complex
Proteins, 81, 2013
7F6W
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Crystal structure of Saccharomyces cerevisiae lysyl-tRNA Synthetase
分子名称: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE, Lysine--tRNA ligase
著者Wu, S, Li, P, Hei, Z, Zheng, L, Wang, J, Fang, P.
登録日2021-06-26
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.607 Å)
主引用文献Human lysyl-tRNA synthetase evolves a dynamic structure that can be stabilized by forming complex.
Cell.Mol.Life Sci., 79, 2022
4O2D
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Crystal structure of aspartyl-tRNA synthetase from Mycobacterium smegmatis with bound aspartic acid
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ASPARTIC ACID, Aspartate--tRNA ligase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2013-12-17
公開日2014-01-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015

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件を2024-07-17に公開中

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