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PDB: 209 件
6ATG
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Insights to complement factor H recruitment by the borrelial CspZ protein as revealed by structural analysis
分子名称: Complement regulator-acquiring surface protein 2 (CRASP-2), HCG40889, isoform CRA_b, ...
著者Liu, A, Yan, H, Wu, Y, Li, Y, Liu, J.
登録日2017-08-29
公開日2018-09-12
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Insights to complement factor H recruitment by the borrelial CspZ protein as revealed by structural analysis
To Be Published
4MUC
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BU of 4muc by Molmil
The 4th and 5th C-terminal domains of Factor H related protein 1
分子名称: Complement factor H-related protein 1, SULFATE ION
著者Bhattacharjee, A, Goldman, A, Kolodziejczyk, R, Jokiranta, T.S.
登録日2013-09-21
公開日2015-02-18
最終更新日2015-05-06
実験手法X-RAY DIFFRACTION (2.897 Å)
主引用文献The Major Autoantibody Epitope on Factor H in Atypical Hemolytic Uremic Syndrome Is Structurally Different from Its Homologous Site in Factor H-related Protein 1, Supporting a Novel Model for Induction of Autoimmunity in This Disease.
J.Biol.Chem., 290, 2015
2G7I
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Structure of Human Complement Factor H Carboxyl Terminal Domains 19-20: a Basis for Atypical Hemolytic Uremic Syndrome
分子名称: Complement factor H
著者Jaakola, V.-P, Jokiranta, T.S, Goldman, A.
登録日2006-02-28
公開日2006-05-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure of complement factor H carboxyl-terminus reveals molecular basis of atypical haemolytic uremic syndrome.
Embo J., 25, 2006
1VVC
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BU of 1vvc by Molmil
C-TERMINAL HALF OF VACCINIA VIRUS COMPLEMENT CONTROL PROTEIN, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: VACCINIA VIRUS COMPLEMENT CONTROL PROTEIN
著者Wiles, A, Campbell, I.D, Barlow, P.N.
登録日1997-06-25
公開日1997-12-03
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献NMR studies of a viral protein that mimics the regulators of complement activation.
J.Mol.Biol., 272, 1997
1VVD
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BU of 1vvd by Molmil
C-TERMINAL HALF OF VACCINIA VIRUS COMPLEMENT CONTROL PROTEIN, NMR, 21 STRUCTURES
分子名称: VACCINIA VIRUS COMPLEMENT CONTROL PROTEIN
著者Wiles, A, Campbell, I.D, Barlow, P.N.
登録日1997-06-25
公開日1997-12-03
最終更新日2024-06-05
実験手法SOLUTION NMR
主引用文献NMR studies of a viral protein that mimics the regulators of complement activation.
J.Mol.Biol., 272, 1997
6ZH1
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BU of 6zh1 by Molmil
Crystal structure of complex between FH19-20 and FhbA protein from Borrelia hermsii
分子名称: 1,2-ETHANEDIOL, Complement factor H, Factor H-binding protein A, ...
著者Kogan, K, Kotila, T, Meri, T, Goldman, A.
登録日2020-06-20
公開日2022-01-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Mechanism of Borrelia immune evasion by FhbA-related proteins.
Plos Pathog., 18, 2022
3KZJ
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BU of 3kzj by Molmil
Structure of complement Factor H variant R1203A
分子名称: Complement factor H, SULFATE ION
著者Bhattacharjee, A, Lehtinen, M.J, Kajander, T, Goldman, A, Jokiranta, T.S.
登録日2009-12-08
公開日2010-05-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Both domain 19 and domain 20 of factor H are involved in binding to complement C3b and C3d
Mol.Immunol., 47, 2010
3KXV
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Structure of complement Factor H variant Q1139A
分子名称: Complement factor H, SULFATE ION
著者Bhattacharjee, A, Lehtinen, M.J, Kajander, T, Goldman, A, Jokiranta, T.S.
登録日2009-12-04
公開日2010-05-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.004 Å)
主引用文献Both domain 19 and domain 20 of factor H are involved in binding to complement C3b and C3d
Mol.Immunol., 47, 2010
8CI3
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BU of 8ci3 by Molmil
Structure of bovine CD46 ectodomain (SCR 1-2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Aitkenhead, H, David I Stuart, D.I, El Omari, K.
登録日2023-02-08
公開日2023-07-12
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Structure of Bovine CD46 Ectodomain.
Viruses, 15, 2023
8CJV
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Structure of bovine CD46 ectodomain (SCR 1-4)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Membrane cofactor protein
著者Aitkenhead, H, Stuart, D.I, El Omari, K.
登録日2023-02-13
公開日2023-07-12
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Structure of Bovine CD46 Ectodomain.
Viruses, 15, 2023
4J38
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Structure of Borrelia burgdorferi Outer surface protein E in complex with Factor H domains 19-20
分子名称: Complement factor H, Outer surface protein E, SULFATE ION
著者Bhattacharjee, A, Kolodziejczyk, R, Kajander, T, Goldman, A, Jokiranta, T.S.
登録日2013-02-05
公開日2013-05-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献Structural Basis for Complement Evasion by Lyme Disease Pathogen Borrelia burgdorferi
J.Biol.Chem., 288, 2013
2QFH
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Solution Structure of the C-terminal SCR-16/20 fragment of Complement Factor H.
分子名称: Complement factor H
著者Okemefuna, A.I, Gilbert, H.E, Griggs, K.M, Ormsby, R.J, Gordon, D.L, Perkins, S.J.
登録日2007-06-27
公開日2007-09-25
最終更新日2024-02-21
実験手法SOLUTION SCATTERING
主引用文献The regulatory SCR-1/5 and cell surface-binding SCR-16/20 fragments of factor H reveal partially folded-back solution structures and different self-associative properties.
J.Mol.Biol., 375, 2008
2QZD
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BU of 2qzd by Molmil
Fitted structure of SCR4 of DAF into cryoEM density
分子名称: Complement decay-accelerating factor
著者Hafenstein, S, Bowman, V.D, Chipman, P.R, Bator Kelly, C.M, Lin, F, Medof, M.E, Rossmann, M.G.
登録日2007-08-16
公開日2007-10-30
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (14 Å)
主引用文献Interaction of decay-accelerating factor with coxsackievirus b3.
J.Virol., 81, 2007
3ERB
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BU of 3erb by Molmil
The Crystal Structure of C2b, a Fragment of Complement Component C2 produced during C3-convertase Formation
分子名称: Complement C2
著者Narayan, S.V.L, Krishnan, V.
登録日2008-10-01
公開日2009-03-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structure of C2b, a fragment of complement component C2 produced during C3 convertase formation
Acta Crystallogr.,Sect.D, 65, 2009
1LY2
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Crystal structure of unliganded human CD21 SCR1-SCR2 (Complement receptor type 2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, complement receptor type 2
著者Prota, A.E, Sage, D.R, Stehle, T, Fingeroth, J.D.
登録日2002-06-06
公開日2002-07-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The crystal structure of human CD21: Implications for Epstein-Barr virus and C3d binding.
Proc.Natl.Acad.Sci.USA, 99, 2002
3GAU
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BU of 3gau by Molmil
Solution structure of Human Complement Factor H in 50 mM NaCl buffer
分子名称: Complement factor H
著者Okemefuna, A.I, Nan, R, Gor, J, Perkins, S.J.
登録日2009-02-18
公開日2009-06-09
最終更新日2024-02-21
実験手法SOLUTION SCATTERING
主引用文献Electrostatic interactions contribute to the folded-back conformation of wild type human factor H.
J.Mol.Biol., 391, 2009
3GAV
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BU of 3gav by Molmil
Solution structure of Human Complement Factor H in 137 mM NaCl buffer
分子名称: Complement factor H
著者Okemefuna, A.I, Nan, R, Gor, J, Perkins, S.J.
登録日2009-02-18
公開日2009-06-09
最終更新日2024-02-21
実験手法SOLUTION SCATTERING
主引用文献Electrostatic interactions contribute to the folded-back conformation of wild type human factor H.
J.Mol.Biol., 391, 2009
6YIO
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BU of 6yio by Molmil
CRYSTAL STRUCTURE OF FAB RG6292 IN COMPLEX WITH CD25 ECD
分子名称: FAB FRAGMENT HEAVY CHAIN, FAB FRGAMENT LIGHT CHAIN, Interleukin-2 receptor subunit alpha
著者Benz, J, Koll, H, Leibrock, L.
登録日2020-04-01
公開日2020-11-11
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献CD25-T reg -depleting antibodies preserving IL-2 signaling on effector T cells enhance effector activation and antitumor immunity.
Nat Cancer, 1, 2020
1CKL
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BU of 1ckl by Molmil
N-TERMINAL TWO DOMAINS OF HUMAN CD46 (MEMBRANE COFACTOR PROTEIN, MCP)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
著者Casasnovas, J, Larvie, M, Stehle, T.
登録日1999-04-22
公開日1999-06-11
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structure of two CD46 domains reveals an extended measles virus-binding surface.
EMBO J., 18, 1999
2A55
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Solution structure of the two N-terminal CCP modules of C4b-binding protein (C4BP) alpha-chain.
分子名称: C4b-binding protein
著者Jenkins, H.T, Mark, L, Ball, G, Lindahl, G, Uhrin, D, Blom, A.M, Barlow, P.N.
登録日2005-06-30
公開日2005-12-13
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Human C4b-binding Protein, Structural Basis for Interaction with Streptococcal M Protein, a Major Bacterial Virulence Factor
J.Biol.Chem., 281, 2006
6ILK
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Cryo-EM structure of Echovirus 6 complexed with its attachment receptor CD55 at PH 7.4
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Gao, G.F, Liu, S, Zhao, X, Peng, R.
登録日2018-10-18
公開日2019-05-15
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B.
Cell, 177, 2019
6ILJ
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Cryo-EM structure of Echovirus 6 complexed with its attachment receptor CD55 at PH 5.5
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Gao, G.F, Liu, S, Zhao, X, Peng, R.
登録日2018-10-18
公開日2019-05-15
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Human Neonatal Fc Receptor Is the Cellular Uncoating Receptor for Enterovirus B.
Cell, 177, 2019
3SW0
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BU of 3sw0 by Molmil
Structure of the C-terminal region (modules 18-20) of complement regulator Factor H
分子名称: Complement factor H, GLYCEROL, PHOSPHATE ION
著者Morgan, H.P, Guariento, M, Schmidt, C.Q, Barlow, P.N, Hannan, J.P.
登録日2011-07-13
公開日2012-03-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Analysis of the C-Terminal Region (Modules 18-20) of Complement Regulator Factor H (FH).
Plos One, 7, 2012
3R62
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Structure of complement regulator Factor H mutant, T1184R.
分子名称: Complement factor H, GLYCEROL
著者Morgan, H.P, Jiang, J, Herbert, A.P, Kavanagh, D, Uhran, D, Barlow, P.N, Hannan, J.P.
登録日2011-03-21
公開日2011-06-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Crystallographic determination of the disease-associated T1184R variant of the complement Factor H.
Acta Crystallogr.,Sect.D, 67, 2011
1E5G
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Solution structure of central CP module pair of a pox virus complement inhibitor
分子名称: COMPLEMENT CONTROL PROTEIN C3
著者Henderson, C.E, Bromek, K, Mullin, N.P, Smith, B.O, Uhrin, D, Barlow, P.N.
登録日2000-07-25
公開日2000-08-31
最終更新日2013-07-03
実験手法SOLUTION NMR
主引用文献Solution Structure and Dynamics of the Central Ccp Module Pair of a Poxvirus Complement Control Protein
J.Mol.Biol., 307, 2001

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