4MUC

The 4th and 5th C-terminal domains of Factor H related protein 1

Summary for 4MUC

Entry DOI	10.2210/pdb4muc/pdb
Descriptor	Complement factor H-related protein 1, SULFATE ION (2 entities in total)
Functional Keywords	sushi domains, complement alternative pathway, factor h related proteins, immune system
Biological source	Homo sapiens (human)
Cellular location	Secreted: Q03591
Total number of polymer chains	2
Total formula weight	29150.94
Authors	Bhattacharjee, A.,Goldman, A.,Kolodziejczyk, R.,Jokiranta, T.S. (deposition date: 2013-09-21, release date: 2015-02-18, Last modification date: 2015-05-06)
Primary citation	Bhattacharjee, A.,Reuter, S.,Trojnar, E.,Kolodziejczyk, R.,Seeberger, H.,Hyvarinen, S.,Uzonyi, B.,Szilagyi, A.,Prohaszka, Z.,Goldman, A.,Jozsi, M.,Jokiranta, T.S. The Major Autoantibody Epitope on Factor H in Atypical Hemolytic Uremic Syndrome Is Structurally Different from Its Homologous Site in Factor H-related Protein 1, Supporting a Novel Model for Induction of Autoimmunity in This Disease. J.Biol.Chem., 290:9500-9510, 2015 Cited by PubMed: 25659429 DOI: 10.1074/jbc.M114.630871 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.897 Å)

Structure validation