5EI0
| Structure of RCL-cleaved vaspin (serpinA12) | 分子名称: | Serpin A12 | 著者 | Pippel, J, Kuettner, B.E, Ulbricht, D, Daberger, J, Schultz, S, Heiker, J.T, Strater, N. | 登録日 | 2015-10-29 | 公開日 | 2015-11-11 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of cleaved vaspin (serpinA12). Biol.Chem., 397, 2016
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3LW2
| Mouse Plasminogen Activator Inhibitor-1 (PAI-1) | 分子名称: | Plasminogen activator inhibitor 1 | 著者 | Dewilde, M, Van De Craen, B, Compernolle, G, Madsen, J.B, Strelkov, S.V, Gils, A, Declerck, P.J. | 登録日 | 2010-02-23 | 公開日 | 2010-04-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Subtle structural differences between human and mouse PAI-1 reveal the basis for biochemical differences. J.Struct.Biol., 171, 2010
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7VLJ
| Crystal structure of Entamoeba histolytica serine protease inhibitor, Histopin, in the cleaved conformation | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, POTASSIUM ION, ... | 著者 | Ali, M.F, Devi, S, Gourinath, S. | 登録日 | 2021-10-03 | 公開日 | 2021-11-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Crystal structure of Entamoeba histolytica serine protease inhibitor, Histopin, in the cleaved conformation To Be Published
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5INW
| Structure of reaction loop cleaved lamprey angiotensinogen | 分子名称: | C-terminal peptide of Putative angiotensinogen, Putative angiotensinogen, SULFATE ION | 著者 | Wei, H, Zhou, A. | 登録日 | 2016-03-08 | 公開日 | 2016-10-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Heparin Binds Lamprey Angiotensinogen and Promotes Thrombin Inhibition through a Template Mechanism J.Biol.Chem., 291, 2016
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6ZRV
| Crystal Structure of Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-W175F) in Complex with an Inhibitory Nanobody (VHH-s-a93, Nb93) | 分子名称: | Plasminogen activator inhibitor 1, VHH-s-a93 (Nb93) | 著者 | Sillen, M, Weeks, S.D, Strelkov, S.V, Declerck, P.J. | 登録日 | 2020-07-15 | 公開日 | 2020-08-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Structural Insights into the Mechanism of a Nanobody That Stabilizes PAI-1 and Modulates Its Activity. Int J Mol Sci, 21, 2020
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7PMU
| Crystal structure of native Iripin-8 | 分子名称: | DI(HYDROXYETHYL)ETHER, HEXAETHYLENE GLYCOL, Serpin-8, ... | 著者 | Polderdijk, S, Kotal, J, Chmelar, J, Huntington, J.A. | 登録日 | 2021-09-02 | 公開日 | 2021-10-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Ixodes ricinus Salivary Serpin Iripin-8 Inhibits the Intrinsic Pathway of Coagulation and Complement. Int J Mol Sci, 22, 2021
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3CWL
| Crystal structure of alpha-1-antitrypsin, crystal form B | 分子名称: | Alpha-1-antitrypsin, CHLORIDE ION | 著者 | Morton, C.J, Hansen, G, Feil, S.C, Adams, J.J, Parker, M.W. | 登録日 | 2008-04-22 | 公開日 | 2008-09-23 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Preventing serpin aggregation: The molecular mechanism of citrate action upon antitrypsin unfolding. Protein Sci., 17, 2008
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6KGA
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6GWQ
| Crystal Structure of Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-stab) in Complex with an Inhibitory Nanobody (VHH-2g-42) | 分子名称: | Plasminogen Activator Inhibitor-1, VHH-2g-42 | 著者 | Sillen, M, Weeks, S.D, Strelkov, S.V, Declerck, P.J. | 登録日 | 2018-06-25 | 公開日 | 2020-01-01 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Molecular mechanism of two nanobodies that inhibit PAI-1 activity reveals a modulation at distinct stages of the PAI-1/plasminogen activator interaction. J.Thromb.Haemost., 18, 2020
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3CWM
| Crystal structure of alpha-1-antitrypsin complexed with citrate | 分子名称: | Alpha-1-antitrypsin, CITRIC ACID | 著者 | Morton, C.J, Hansen, G, Feil, S.C, Adams, J.J, Parker, M.W. | 登録日 | 2008-04-22 | 公開日 | 2008-09-23 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Preventing serpin aggregation: The molecular mechanism of citrate action upon antitrypsin unfolding. Protein Sci., 17, 2008
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7NPL
| ALPHA-1 ANTITRYPSIN (C232S) COMPLEXED WITH cmpd 11 | 分子名称: | Alpha-1-antitrypsin, GLYCEROL, N-((1S,2R)-1-(3-chloro-2-methylphenyl)-1-hydroxypentan-2-yl)-2-oxoindoline-4-carboxamide | 著者 | Chung, C. | 登録日 | 2021-02-27 | 公開日 | 2021-04-07 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | The development of highly potent and selective small molecule correctors of Z alpha 1 -antitrypsin misfolding. Bioorg.Med.Chem.Lett., 41, 2021
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6GWP
| Crystal Structure of Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-stab) in Complex with Two Inhibitory Nanobodies (VHH-2g-42, VHH-2w-64) | 分子名称: | Plasminogen Activator Inhibitor-1, VHH-2g-42, VHH-2w-64 | 著者 | Sillen, M, Weeks, S.D, Strelkov, S.V, Declerck, P.J. | 登録日 | 2018-06-25 | 公開日 | 2020-01-01 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Molecular mechanism of two nanobodies that inhibit PAI-1 activity reveals a modulation at distinct stages of the PAI-1/plasminogen activator interaction. J.Thromb.Haemost., 18, 2020
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7NPK
| ALPHA-1 ANTITRYPSIN C232S COMPLEXED WITH CMPD3 | 分子名称: | Alpha-1-antitrypsin, GLYCEROL, N-((1S,2R)-1-hydroxy-1-(o-tolyl)pentan-2-yl)-2-oxo-2,3-dihydrobenzo[d]oxazole-5-carboxamide | 著者 | Chung, C. | 登録日 | 2021-02-27 | 公開日 | 2021-04-07 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | The development of highly potent and selective small molecule correctors of Z alpha 1 -antitrypsin misfolding. Bioorg.Med.Chem.Lett., 41, 2021
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6SSV
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5HGC
| A Serpin structure | 分子名称: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranose, SULFATE ION, ... | 著者 | Das, S, Vashchenko, G.V, Van Petegem, F. | 登録日 | 2016-01-08 | 公開日 | 2016-04-06 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | A Serpin structure J.Biol.Chem., 2016
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6BJ5
| Structure of the Clinically used Myxomaviral Serine Protease Inhibitor 1 (SERP-1) | 分子名称: | 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Mahon, B.P, Lomelino, C.L, McKenna, R. | 登録日 | 2017-11-05 | 公開日 | 2018-11-07 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of the Clinically used Myxomaviral Serine Protease Inhibitor 1 (SERP-1) To Be Published
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6LOS
| Crystal structure of mouse PEDF in complex with heterotrimeric collagen model peptide. | 分子名称: | Collagen model peptide, type I, alpha 1, ... | 著者 | Kawahara, K, Maruno, T, Oki, H, Yoshida, T, Ohkubo, T, Koide, T, Kobayashi, Y. | 登録日 | 2020-01-07 | 公開日 | 2020-09-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.476 Å) | 主引用文献 | Spatiotemporal regulation of PEDF signaling by type I collagen remodeling. Proc.Natl.Acad.Sci.USA, 117, 2020
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4P0O
| Cleaved Serpin 42Da | 分子名称: | Serine protease inhibitor 4, isoform B | 著者 | Ellisdon, A.M, Whisstock, J.C. | 登録日 | 2014-02-21 | 公開日 | 2014-05-07 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | High resolution structure of cleaved Serpin 42 Da from Drosophila melanogaster. Bmc Struct.Biol., 14, 2014
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4P0F
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6ROD
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6CJ7
| Crystal structure of Manduca sexta Serine protease inhibitor (Serpin)-12 | 分子名称: | Serpin-12 | 著者 | Gulati, M, Hu, Y, Peng, S, Pathak, P.K, Wang, Y, Deng, J, Jiang, H. | 登録日 | 2018-02-26 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Manduca sexta serpin-12 controls the prophenoloxidase activation system in larval hemolymph. Insect Biochem. Mol. Biol., 99, 2018
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5IO1
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3LE2
| Structure of Arabidopsis AtSerpin1. Native Stressed Conformation | 分子名称: | ACETATE ION, GLYCEROL, SULFATE ION, ... | 著者 | Harrop, S.J, Joss, T.V, Cumi, P.M.G, Roberts, T.H. | 登録日 | 2010-01-14 | 公開日 | 2010-02-23 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Arabidopsis AtSerpin1, crystal structure and in vivo interaction with its target protease RESPONSIVE TO DESICCATION-21 (RD21). J.Biol.Chem., 285, 2010
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9API
| THE S VARIANT OF HUMAN ALPHA1-ANTITRYPSIN, STRUCTURE AND IMPLICATIONS FOR FUNCTION AND METABOLISM | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA 1-ANTITRYPSIN, ... | 著者 | Loebermann, H, Tokuoka, R, Deisenhofer, J, Huber, R. | 登録日 | 1988-09-08 | 公開日 | 1990-10-15 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The S variant of human alpha 1-antitrypsin, structure and implications for function and metabolism. Protein Eng., 2, 1989
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9PAI
| CLEAVED SUBSTRATE VARIANT OF PLASMINOGEN ACTIVATOR INHIBITOR-1 | 分子名称: | PROTEIN (PLASMINOGEN ACTIVATOR INHIBITOR-1) residues 19-364, PROTEIN (PLASMINOGEN ACTIVATOR INHIBITOR-1) residues 365-397 | 著者 | Aertgeerts, K, De Bondt, H.L, De Ranter, C.J, Declerck, P.J. | 登録日 | 1999-03-11 | 公開日 | 1999-03-19 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Mechanisms contributing to the conformational and functional flexibility of plasminogen activator inhibitor-1. Nat.Struct.Biol., 2, 1995
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