1P1N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1p1n by Molmil](/molmil-images/mine/1p1n) | |
1PB7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1pb7 by Molmil](/molmil-images/mine/1pb7) | |
8E94
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8e94 by Molmil](/molmil-images/mine/8e94) | PYD-106-bound Human GluN1a-GluN2C NMDA receptor in intact conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Chou, T.-H, Furukawa, H. | 登録日 | 2022-08-26 | 公開日 | 2022-12-07 | 最終更新日 | 2022-12-14 | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | 主引用文献 | Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Mol.Cell, 82, 2022
|
|
8E93
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8e93 by Molmil](/molmil-images/mine/8e93) | D-cycloserine and glutamate bound Human GluN1a-GluN2C NMDA receptor in splayed conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | 著者 | Chou, T.-H, Furukawa, H. | 登録日 | 2022-08-26 | 公開日 | 2022-12-07 | 最終更新日 | 2022-12-14 | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | 主引用文献 | Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Mol.Cell, 82, 2022
|
|
8E97
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8e97 by Molmil](/molmil-images/mine/8e97) | PYD-106-bound Human GluN1a-GluN2C NMDA receptor in splayed conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | 著者 | Chou, T.-H, Furukawa, H. | 登録日 | 2022-08-26 | 公開日 | 2022-12-07 | 最終更新日 | 2022-12-14 | 実験手法 | ELECTRON MICROSCOPY (4.19 Å) | 主引用文献 | Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Mol.Cell, 82, 2022
|
|
8E92
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8e92 by Molmil](/molmil-images/mine/8e92) | D-cycloserine and glutamate bound Human GluN1a-GluN2C NMDA receptor in intact conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | 著者 | Chou, T.-H, Furukawa, H. | 登録日 | 2022-08-26 | 公開日 | 2022-12-07 | 最終更新日 | 2022-12-14 | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | 主引用文献 | Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Mol.Cell, 82, 2022
|
|
8E99
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8e99 by Molmil](/molmil-images/mine/8e99) | Human GluN1a-GluN2A-GluN2C triheteromeric NMDA receptor in complex with Nb-4 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | 著者 | Chou, T.-H, Furukawa, H. | 登録日 | 2022-08-26 | 公開日 | 2022-12-07 | 最終更新日 | 2022-12-14 | 実験手法 | ELECTRON MICROSCOPY (4.24 Å) | 主引用文献 | Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Mol.Cell, 82, 2022
|
|
8E98
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8e98 by Molmil](/molmil-images/mine/8e98) | D-cycloserine and glutamate bound Human GluN1a-GluN2C NMDA receptor in nanodisc - intact conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, NMDA 1, ... | 著者 | Chou, T.-H, Furukawa, H. | 登録日 | 2022-08-26 | 公開日 | 2022-12-07 | 最終更新日 | 2022-12-14 | 実験手法 | ELECTRON MICROSCOPY (3.75 Å) | 主引用文献 | Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Mol.Cell, 82, 2022
|
|
8E96
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8e96 by Molmil](/molmil-images/mine/8e96) | Glycine and glutamate bound Human GluN1a-GluN2D NMDA receptor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, GLYCINE, ... | 著者 | Kang, H, Furukawa, H. | 登録日 | 2022-08-26 | 公開日 | 2022-12-07 | 最終更新日 | 2022-12-14 | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | 主引用文献 | Structural insights into assembly and function of GluN1-2C, GluN1-2A-2C, and GluN1-2D NMDARs. Mol.Cell, 82, 2022
|
|
8F0O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8f0o by Molmil](/molmil-images/mine/8f0o) | |
8FWS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fws by Molmil](/molmil-images/mine/8fws) | Structure of the ligand-binding and transmembrane domains of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344 | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Gangwar, S.P, Yen, L.Y, Yelshanskaya, M.V, Sobolevsky, A.I. | 登録日 | 2023-01-23 | 公開日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | 主引用文献 | Positive and negative allosteric modulation of GluK2 kainate receptors by BPAM344 and antiepileptic perampanel. Cell Rep, 42, 2023
|
|
8FWQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fwq by Molmil](/molmil-images/mine/8fwq) | Structure of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-cyclopropyl-7-fluoro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide, ... | 著者 | Gangwar, S.P, Yen, L.Y, Yelshanskaya, M.V, Sobolevsky, A.I. | 登録日 | 2023-01-23 | 公開日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | 主引用文献 | Positive and negative allosteric modulation of GluK2 kainate receptors by BPAM344 and antiepileptic perampanel. Cell Rep, 42, 2023
|
|
8FWW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fww by Molmil](/molmil-images/mine/8fww) | Structure of the ligand-binding and transmembrane domains of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344 and noncompetitive inhibitor perampanel | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-(6'-oxo-1'-phenyl[1',6'-dihydro[2,3'-bipyridine]]-5'-yl)benzonitrile, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Gangwar, S.P, Yen, L.Y, Yelshanskaya, M.V, Sobolevsky, A.I. | 登録日 | 2023-01-23 | 公開日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Positive and negative allosteric modulation of GluK2 kainate receptors by BPAM344 and antiepileptic perampanel. Cell Rep, 42, 2023
|
|
8FWT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fwt by Molmil](/molmil-images/mine/8fwt) | Structure of the amino terminal domain of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344 and competitive antagonist DNQX | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | 著者 | Yen, L.Y, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I. | 登録日 | 2023-01-23 | 公開日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | 主引用文献 | Positive and negative allosteric modulation of GluK2 kainate receptors by BPAM344 and antiepileptic perampanel. Cell Rep, 42, 2023
|
|
8FWR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fwr by Molmil](/molmil-images/mine/8fwr) | Structure of the amino-terminal domain of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, kainate 2, ... | 著者 | Gangwar, S.P, Yen, L.Y, Yelshanskaya, M.V, Sobolevsky, A.I. | 登録日 | 2023-01-23 | 公開日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Positive and negative allosteric modulation of GluK2 kainate receptors by BPAM344 and antiepileptic perampanel. Cell Rep, 42, 2023
|
|
8FWV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fwv by Molmil](/molmil-images/mine/8fwv) | Structure of the amino-terminal domain of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344 and noncompetitive inhibitor perampanel | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... | 著者 | Gangwar, S.P, Yen, L.Y, Yelshanskaya, M.V, Sobolevsky, A.I. | 登録日 | 2023-01-23 | 公開日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | 主引用文献 | Positive and negative allosteric modulation of GluK2 kainate receptors by BPAM344 and antiepileptic perampanel. Cell Rep, 42, 2023
|
|
8FWU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fwu by Molmil](/molmil-images/mine/8fwu) | Structure of the ligand-binding and transmembrane domains of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344 and competitive antagonist DNQX | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Yen, L.Y, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I. | 登録日 | 2023-01-23 | 公開日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | 主引用文献 | Positive and negative allosteric modulation of GluK2 kainate receptors by BPAM344 and antiepileptic perampanel. Cell Rep, 42, 2023
|
|
8FPC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fpc by Molmil](/molmil-images/mine/8fpc) | Conformation 1 of the ligand binding domain (LBDconf1) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg) | 分子名称: | CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2 | 著者 | Nakagawa, T. | 登録日 | 2023-01-04 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.78 Å) | 主引用文献 | The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
|
|
8FP4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fp4 by Molmil](/molmil-images/mine/8fp4) | |
8FPH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fph by Molmil](/molmil-images/mine/8fph) | Conformation 2 of the ligand binding domain (LBDconf2) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg) | 分子名称: | CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2 | 著者 | Nakagawa, T. | 登録日 | 2023-01-04 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
|
|
8FP9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fp9 by Molmil](/molmil-images/mine/8fp9) | GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100mM glutamate (Open-CaNaMg) | 分子名称: | CALCIUM ION, CHLORIDE ION, Glutamate receptor 2, ... | 著者 | Nakagawa, T. | 登録日 | 2023-01-04 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.44 Å) | 主引用文献 | The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
|
|
8FQ5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fq5 by Molmil](/molmil-images/mine/8fq5) | |
8FPL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fpl by Molmil](/molmil-images/mine/8fpl) | LBD conformation 2 (LBDconf2) of GluA2 flip Q isoform of AMPA receptor in complex with gain-of-function TARP gamma-2, with 10mM CaCl2, 150mM NaCl, 1mM MgCl2, 330uM CTZ, and 100uM CNQX (Closed-CaNaMg) | 分子名称: | 6-(aminomethyl)-7-nitro-1,4-dihydroquinoxaline-2,3-dione, CYCLOTHIAZIDE, Glutamate receptor 2 | 著者 | Nakagawa, T. | 登録日 | 2023-01-04 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.81 Å) | 主引用文献 | The open gate of the AMPA receptor forms a Ca 2+ binding site critical in regulating ion transport. Nat.Struct.Mol.Biol., 31, 2024
|
|
8FQF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fqf by Molmil](/molmil-images/mine/8fqf) | |
8FQ8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fq8 by Molmil](/molmil-images/mine/8fq8) | |