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PDB: 672 件

4IGT
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Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with the agonist ZA302 at 1.24A resolution
分子名称: (4R)-4-{3-[hydroxy(methyl)amino]-3-oxopropyl}-L-glutamic acid, GLYCEROL, Glutamate receptor 2, ...
著者Larsen, A.P, Venskutonyte, R, Gajhede, M, Kastrup, J.S, Frydenvang, K.
登録日2012-12-18
公開日2013-03-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献Chemoenzymatic synthesis of new 2,4-syn-functionalized (S)-glutamate analogues and structure-activity relationship studies at ionotropic glutamate receptors and excitatory amino acid transporters.
J.Med.Chem., 56, 2013
4IO2
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BU of 4io2 by Molmil
Crystal Structure of the AvGluR1 ligand binding domain complex with glutamate at 1.37 Angstrom resolution
分子名称: CHLORIDE ION, GLUTAMIC ACID, Glutamate receptor 1
著者Lomash, S, Chittori, S, Mayer, M.L.
登録日2013-01-07
公開日2013-02-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Anions Mediate Ligand Binding in Adineta vaga Glutamate Receptor Ion Channels.
Structure, 21, 2013
4IO3
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Crystal Structure of the AvGluR1 ligand binding domain complex with aspartate at 1.66 Angstrom resolution
分子名称: ASPARTIC ACID, AvGluR1 ligand binding domain, CHLORIDE ION
著者Lomash, S, Chittori, S, Mayer, M.L.
登録日2013-01-07
公開日2013-02-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Anions Mediate Ligand Binding in Adineta vaga Glutamate Receptor Ion Channels.
Structure, 21, 2013
4IY5
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BU of 4iy5 by Molmil
Crystal structure of the glua2 ligand-binding domain (S1S2J-L483Y-N754S) in complex with glutamate and CX516 at 2.0 A resolution
分子名称: CHLORIDE ION, GLUTAMIC ACID, GLYCEROL, ...
著者Krintel, C, Frydenvang, K, Harpsoe, K, Gajhede, M, Kastrup, J.S.
登録日2013-01-28
公開日2013-10-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural analysis of the positive AMPA receptor modulators CX516 and Me-CX516 in complex with the GluA2 ligand-binding domain
Acta Crystallogr.,Sect.D, 69, 2013
4IY6
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Crystal structure of the GLUA2 ligand-binding domain (S1S2J-L483Y-N754S) in complex with glutamate and ME-CX516 at 1.72 A resolution
分子名称: GLUTAMIC ACID, GLYCEROL, Glutamate receptor 2, ...
著者Krintel, C, Frydenvang, K, Harpsoe, K, Gajhede, M, Kastrup, J.S.
登録日2013-01-28
公開日2013-10-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Structural analysis of the positive AMPA receptor modulators CX516 and Me-CX516 in complex with the GluA2 ligand-binding domain
Acta Crystallogr.,Sect.D, 69, 2013
7RZ8
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BU of 7rz8 by Molmil
Structure of the complex of LBD-TMD part of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to agonist quisqualate
分子名称: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Glutamate receptor 2
著者Klykov, O.V, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2021-08-27
公開日2021-10-27
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L.
Mol.Cell, 81, 2021
7RZA
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BU of 7rza by Molmil
Structure of the complex of AMPA receptor GluA2 with auxiliary subunit GSG1L bound to agonist quisqualate
分子名称: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 2
著者Gangwar, S.P, Klykov, O.V, Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2021-08-27
公開日2021-10-27
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (4.26 Å)
主引用文献Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L.
Mol.Cell, 81, 2021
7RZ6
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Structure of the complex of AMPA receptor GluA2 with auxiliary subunit TARP gamma-5 bound to agonist glutamate
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, GLUTAMIC ACID, Glutamate receptor 2
著者Klykov, O.V, Gangwar, S.P, Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2021-08-27
公開日2021-10-27
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structure and desensitization of AMPA receptor complexes with type II TARP gamma 5 and GSG1L.
Mol.Cell, 81, 2021
7SAB
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BU of 7sab by Molmil
Phencyclidine-bound GluN1a-GluN2B NMDA receptors
分子名称: 1-(PHENYL-1-CYCLOHEXYL)PIPERIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Chou, T.-H, Furukawa, H.
登録日2021-09-22
公開日2022-07-20
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structural insights into binding of therapeutic channel blockers in NMDA receptors.
Nat.Struct.Mol.Biol., 29, 2022
7SAD
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Memantine-bound GluN1a-GluN2B NMDA receptors
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ...
著者Chou, T.-H, Furukawa, H.
登録日2021-09-22
公開日2022-07-20
実験手法ELECTRON MICROSCOPY (3.96 Å)
主引用文献Structural insights into binding of therapeutic channel blockers in NMDA receptors.
Nat.Struct.Mol.Biol., 29, 2022
7SAA
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Glycine and glutamate bound GluN1a-GluN2B NMDA receptors in non-active 1 conformation at 2.97 Angstrom resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ...
著者Chou, T.-H, Furukawa, H.
登録日2021-09-22
公開日2022-07-20
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Structural insights into binding of therapeutic channel blockers in NMDA receptors.
Nat.Struct.Mol.Biol., 29, 2022
7SAC
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BU of 7sac by Molmil
S-(+)-ketamine bound GluN1a-GluN2B NMDA receptors at 3.69 Angstrom resolution
分子名称: (2~{S})-2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Chou, T.-H, Furukawa, H.
登録日2021-09-22
公開日2022-07-20
最終更新日2022-10-26
実験手法ELECTRON MICROSCOPY (3.69 Å)
主引用文献Structural insights into binding of therapeutic channel blockers in NMDA receptors.
Nat.Struct.Mol.Biol., 29, 2022
7TEQ
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BU of 7teq by Molmil
Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 active conformation
分子名称: Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ...
著者Tajima, N, Furukawa, H.
登録日2022-01-05
公開日2022-03-02
実験手法ELECTRON MICROSCOPY (7.51 Å)
主引用文献Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
7TE9
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BU of 7te9 by Molmil
Cryo-EM structure of GluN1b-2B NMDAR complexed to Fab2 class1
分子名称: Fab2 heavy chain, Fab2 light chain, Glutamate receptor ionotropic, ...
著者Tajima, N, Furukawa, H.
登録日2022-01-04
公開日2022-03-02
実験手法ELECTRON MICROSCOPY (3.92 Å)
主引用文献Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
7TES
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BU of 7tes by Molmil
Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 in Non-active1 conformation
分子名称: Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ...
著者Tajima, N, Furukawa, H.
登録日2022-01-05
公開日2022-03-02
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
7TEB
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BU of 7teb by Molmil
Cryo-EM structure of GluN1b-2B NMDAR complexed to Fab2 non-active1-like
分子名称: Fab2 heavy chain, Fab2 light chain, Glutamate receptor ionotropic, ...
著者Tajima, N, Furukawa, H.
登録日2022-01-04
公開日2022-03-02
実験手法ELECTRON MICROSCOPY (4.23 Å)
主引用文献Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
7TER
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BU of 7ter by Molmil
Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 non-active2 conformation
分子名称: Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ...
著者Tajima, N, Furukawa, H.
登録日2022-01-05
公開日2022-03-02
実験手法ELECTRON MICROSCOPY (5.23 Å)
主引用文献Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
7TEE
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BU of 7tee by Molmil
Cryo-EM structure of GluN1b-2B NMDAR complexed to Fab2 Non-active2-like
分子名称: Fab2 heavy chain, Fab2 light chain, Glutamate receptor ionotropic, ...
著者Tajima, N, Furukawa, H.
登録日2022-01-04
公開日2022-03-02
実験手法ELECTRON MICROSCOPY (6.59 Å)
主引用文献Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
7TET
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BU of 7tet by Molmil
Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 in non-active2-like conformation
分子名称: Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ...
著者Tajima, N, Furukawa, H.
登録日2022-01-05
公開日2022-03-02
実験手法ELECTRON MICROSCOPY (4.45 Å)
主引用文献Development and characterization of functional antibodies targeting NMDA receptors.
Nat Commun, 13, 2022
7TNP
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BU of 7tnp by Molmil
Complex GGGG of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (3.96 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNK
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Complex GNNN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNM
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Complex GNGN2 of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (4.74 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNO
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Complex GGGN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (4.02 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNN
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BU of 7tnn by Molmil
Complex GGNN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNL
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Complex GNGN1 of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022

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