4TNC
 
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6LKZ
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7X2U
 | | Structure of a human NHE3-CHP1 complex in the autoinhibited state | | 分子名称: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, Calcineurin B homologous protein 1, Sodium/hydrogen exchanger 3, ... | | 著者 | Dong, Y, Li, H, Gao, Y, Zhang, X.C, Zhao, Y. | | 登録日 | 2022-02-26 | | 公開日 | 2022-04-20 | | 最終更新日 | 2022-04-27 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure of a human NHE3-CHP1 complex in the autoinhibited state
Sci Adv, 2022
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4IL1
 | | Crystal Structure of the Rat Calcineurin | | 分子名称: | CALCIUM ION, Calmodulin, Calcineurin subunit B type 1, ... | | 著者 | Ye, Q, Faucher, F, Jia, Z. | | 登録日 | 2012-12-28 | | 公開日 | 2013-10-02 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural basis of calcineurin activation by calmodulin.
Cell Signal, 25, 2013
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1SYM
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4ICB
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6EPA
 | | Structure of dNCS-1 bound to the NCS-1/Ric8a protein/protein interaction regulator IGS-1.76 | | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, CALCIUM ION, FI18190p1, ... | | 著者 | Sanchez-Barrena, M.J, Daniel, M, Infantes, L. | | 登録日 | 2017-10-11 | | 公開日 | 2018-08-29 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Deciphering the Inhibition of the Neuronal Calcium Sensor 1 and the Guanine Exchange Factor Ric8a with a Small Phenothiazine Molecule for the Rational Generation of Therapeutic Synapse Function Regulators.
J. Med. Chem., 61, 2018
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4WPX
 | | Chaetomium theromophilum TREX2 CID domain complex | | 分子名称: | Cell division control protein 31-like protein, Putative SAC3 family protein, Putative uncharacterized protein | | 著者 | Valkov, E, Stewart, M. | | 登録日 | 2014-10-21 | | 公開日 | 2015-06-17 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | | 主引用文献 | Structural Characterization of the Chaetomium thermophilum TREX-2 Complex and its Interaction with the mRNA Nuclear Export Factor Mex67:Mtr2.
Structure, 23, 2015
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4XYN
 | | X-ray structure of Ca(2+)-S100B with human RAGE-derived W61 peptide | | 分子名称: | CALCIUM ION, Protein S100-B, Receptor for advanced glycation endproducts-derived peptide (W61) | | 著者 | Jensen, J.L, Indurthi, V.S.K, Neau, D, Vetter, S.W, Colbert, C.L. | | 登録日 | 2015-02-02 | | 公開日 | 2015-05-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Structural insights into the binding of the human receptor for advanced glycation end products (RAGE) by S100B, as revealed by an S100B-RAGE-derived peptide complex.
Acta Crystallogr.,Sect.D, 71, 2015
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4DS7
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4BY5
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4FQO
 | | Crystal Structure of Calcium-Loaded S100B Bound to SBi4211 | | 分子名称: | 4,4'-[heptane-1,7-diylbis(oxy)]dibenzenecarboximidamide, CALCIUM ION, Protein S100-B | | 著者 | McKnight, L.E, Raman, E.P, Bezawada, P, Kudrimoti, S, Wilder, P.T, Hartman, K.G, Toth, E.A, Coop, A, MacKerrell, A.D, Weber, D.J. | | 登録日 | 2012-06-25 | | 公開日 | 2012-10-17 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structure-Based Discovery of a Novel Pentamidine-Related Inhibitor of the Calcium-Binding Protein S100B.
ACS Med Chem Lett, 3, 2012
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4BY4
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6FIE
 | | Crystallographic structure of calcium loaded Calbindin-D28K. | | 分子名称: | CALCIUM ION, Calbindin, THIOCYANATE ION | | 著者 | Noble, J.W, Almalki, R, Roe, S.M, Wagner, A, Dumanc, R, Atack, J.R. | | 登録日 | 2018-01-18 | | 公開日 | 2018-10-10 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | The X-ray structure of human calbindin-D28K: an improved model.
Acta Crystallogr D Struct Biol, 74, 2018
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5G08
 | | Crystal structure of Drosophila NCS-1 bound to chlorpromazine | | 分子名称: | 1,2-ETHANEDIOL, 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine, CALCIUM ION, ... | | 著者 | Chaves-Sanjuan, A, Infantes, L, Sanchez-Barrena, M.J. | | 登録日 | 2016-03-17 | | 公開日 | 2017-01-25 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | | 主引用文献 | Interference of the complex between NCS-1 and Ric8a with phenothiazines regulates synaptic function and is an approach for fragile X syndrome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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8S9W
 | | Murine S100A7/S100A15 in presence of calcium | | 分子名称: | ACETATE ION, CALCIUM ION, GLYCEROL, ... | | 著者 | Harrison, S.A, Naretto, A, Balakrishnan, S, Chazin, W.J. | | 登録日 | 2023-03-30 | | 公開日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Comparative analysis of the physical properties of murine and human S100A7: Insight into why zinc piracy is mediated by human but not murine S100A7.
J.Biol.Chem., 299, 2023
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3OX5
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3OX6
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8VK3
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5G4P
 | | Crystal structure of human hippocalcin at 2.4 A resolution | | 分子名称: | CALCIUM ION, Neuron-specific calcium-binding protein hippocalcin | | 著者 | Antonyuk, S.V, Helassa, N, Lian, L.Y, Haynes, L.P, Burgoyne, R.D. | | 登録日 | 2016-05-15 | | 公開日 | 2017-05-03 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | | 主引用文献 | Biophysical and functional characterization of hippocalcin mutants responsible for human dystonia.
Hum. Mol. Genet., 26, 2017
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5G58
 | | Crystal structure of A190T mutant of human hippocalcin AT 2.5 A resolution | | 分子名称: | CALCIUM ION, Neuron-specific calcium-binding protein hippocalcin | | 著者 | Antonyuk, S.V, Helassa, N, Lian, L.Y, Haynes, L.P, Burgoyne, R.D. | | 登録日 | 2016-05-22 | | 公開日 | 2017-05-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | | 主引用文献 | Biophysical and functional characterization of hippocalcin mutants responsible for human dystonia.
Hum. Mol. Genet., 26, 2017
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8VK4
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3RM1
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6WXU
 | | CryoEM structure of mouse DUOX1-DUOXA1 complex in the dimer-of-dimer state | | 分子名称: | 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | | 著者 | Sun, J. | | 登録日 | 2020-05-12 | | 公開日 | 2020-09-02 | | 最終更新日 | 2021-03-17 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structures of mouse DUOX1-DUOXA1 provide mechanistic insights into enzyme activation and regulation.
Nat.Struct.Mol.Biol., 27, 2020
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6WXR
 | | CryoEM structure of mouse DUOX1-DUOXA1 complex in the absence of NADPH | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Dual oxidase 1, Dual oxidase maturation factor 1, ... | | 著者 | Sun, J. | | 登録日 | 2020-05-11 | | 公開日 | 2020-09-02 | | 最終更新日 | 2021-03-17 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structures of mouse DUOX1-DUOXA1 provide mechanistic insights into enzyme activation and regulation.
Nat.Struct.Mol.Biol., 27, 2020
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