4FQO
Crystal Structure of Calcium-Loaded S100B Bound to SBi4211
Summary for 4FQO
Entry DOI | 10.2210/pdb4fqo/pdb |
Related | 3CR4 |
Descriptor | Protein S100-B, CALCIUM ION, 4,4'-[heptane-1,7-diylbis(oxy)]dibenzenecarboximidamide, ... (4 entities in total) |
Functional Keywords | protein-inhibitor complex, ef-hand protein, calcium binding protein, protein binding-inhibitor complex, protein binding/inhibitor |
Biological source | Bos taurus (bovine) |
Cellular location | Cytoplasm: P02638 |
Total number of polymer chains | 1 |
Total formula weight | 10734.23 |
Authors | McKnight, L.E.,Raman, E.P.,Bezawada, P.,Kudrimoti, S.,Wilder, P.T.,Hartman, K.G.,Toth, E.A.,Coop, A.,MacKerrell, A.D.,Weber, D.J. (deposition date: 2012-06-25, release date: 2012-10-17, Last modification date: 2024-03-13) |
Primary citation | McKnight, L.E.,Raman, E.P.,Bezawada, P.,Kudrimoti, S.,Wilder, P.T.,Hartman, K.G.,Godoy-Ruiz, R.,Toth, E.A.,Coop, A.,Mackerell, A.D.,Weber, D.J. Structure-Based Discovery of a Novel Pentamidine-Related Inhibitor of the Calcium-Binding Protein S100B. ACS Med Chem Lett, 3:975-979, 2012 Cited by PubMed: 23264854DOI: 10.1021/ml300166s PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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