6AEX
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![BU of 6aex by Molmil](/molmil-images/mine/6aex) | Crystal structure of unoccupied murine uPAR | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor | 著者 | Min, L, Huang, M. | 登録日 | 2018-08-06 | 公開日 | 2019-07-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.393 Å) | 主引用文献 | Crystal structure of the unoccupied murine urokinase-type plasminogen activator receptor (uPAR) reveals a tightly packed DII-DIII unit. Febs Lett., 593, 2019
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7V63
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![BU of 7v63 by Molmil](/molmil-images/mine/7v63) | Structure of dimeric uPAR at low pH | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor | 著者 | Yuan, C, Huang, M. | 登録日 | 2021-08-19 | 公開日 | 2021-12-22 | 最終更新日 | 2022-04-06 | 実験手法 | X-RAY DIFFRACTION (2.906 Å) | 主引用文献 | Crystal structure and cellular functions of uPAR dimer Nat Commun, 13, 2022
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1YWH
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![BU of 1ywh by Molmil](/molmil-images/mine/1ywh) | crystal structure of urokinase plasminogen activator receptor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Llinas, P, Le Du, M.H, Gardsvoll, H, Dano, K, Ploug, M, Gilquin, B, Stura, E.A, Menez, A. | 登録日 | 2005-02-18 | 公開日 | 2005-05-10 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of the human urokinase plasminogen activator receptor bound to an antagonist peptide EMBO J., 24, 2005
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7E17
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![BU of 7e17 by Molmil](/molmil-images/mine/7e17) | Structure of dimeric uPAR | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor | 著者 | Cai, Y, Huang, M. | 登録日 | 2021-02-01 | 公開日 | 2021-12-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | 主引用文献 | Crystal structure and cellular functions of uPAR dimer Nat Commun, 13, 2022
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4QTI
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![BU of 4qti by Molmil](/molmil-images/mine/4qti) | Crystal structure of human uPAR in complex with anti-uPAR Fab 8B12 | 分子名称: | Urokinase plasminogen activator surface receptor, anti-uPAR antibody, heavy chain, ... | 著者 | Zhao, B, Yuan, C, Luo, Z, Huang, M. | 登録日 | 2014-07-08 | 公開日 | 2015-02-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Stabilizing a flexible interdomain hinge region harboring the SMB binding site drives uPAR into its closed conformation. J.Mol.Biol., 427, 2015
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6ION
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![BU of 6ion by Molmil](/molmil-images/mine/6ion) | The complex of C4.4A with its antibody 11H10 Fab fragment | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ly6/PLAUR domain-containing protein 3, ... | 著者 | Huang, M.D, Jiang, Y.B, Yuan, C, Lin, L. | 登録日 | 2018-10-30 | 公開日 | 2020-01-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Crystal Structures of Human C4.4A Reveal the Unique Association of Ly6/uPAR/alpha-neurotoxin Domain Int J Biol Sci, 16, 2020
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6IOM
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![BU of 6iom by Molmil](/molmil-images/mine/6iom) | Crystal structure of human C4.4A | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ly6/PLAUR domain-containing protein 3 | 著者 | Huang, M.D, Jiang, Y.B, Yuan, C, Lin, L. | 登録日 | 2018-10-30 | 公開日 | 2020-01-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.594 Å) | 主引用文献 | Crystal Structures of Human C4.4A Reveal the Unique Association of Ly6/uPAR/alpha-neurotoxin Domain Int J Biol Sci, 16, 2020
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2J8B
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![BU of 2j8b by Molmil](/molmil-images/mine/2j8b) | High resolution structure of human CD59 | 分子名称: | CD59 GLYCOPROTEIN | 著者 | Leath, K.J, Johnson, S, Roversi, P, Morgan, B.P, Smith, R.A.G, Lea, S.M. | 登録日 | 2006-10-24 | 公開日 | 2007-08-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | High-Resolution Structures of Bacterially Expressed Soluble Human Cd59. Acta Crystallogr.,Sect.F, 63, 2007
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7BPR
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![BU of 7bpr by Molmil](/molmil-images/mine/7bpr) | Crystal structure of human TEX101 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PLATINUM (II) ION, Testis-expressed protein 101 | 著者 | Masutani, M, Sakurai, S, Shimizu, T, Ohto, U. | 登録日 | 2020-03-23 | 公開日 | 2020-07-15 | 最終更新日 | 2020-12-23 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structure of TEX101, a glycoprotein essential for male fertility, reveals the presence of tandemly arranged Ly6/uPAR domains. Febs Lett., 594, 2020
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7BPS
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![BU of 7bps by Molmil](/molmil-images/mine/7bps) | Crystal structure of mouse TEX101 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Testis-expressed protein 101, ... | 著者 | Masutani, M, Sakurai, S, Shimizu, T, Ohto, U. | 登録日 | 2020-03-23 | 公開日 | 2020-07-15 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Crystal structure of TEX101, a glycoprotein essential for male fertility, reveals the presence of tandemly arranged Ly6/uPAR domains. Febs Lett., 594, 2020
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3U74
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![BU of 3u74 by Molmil](/molmil-images/mine/3u74) | Crystal structure of stabilized human uPAR mutant | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor | 著者 | Huang, M.D, Xu, X, Yuan, C. | 登録日 | 2011-10-13 | 公開日 | 2012-04-18 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Crystal structure of the urokinase receptor in a ligand-free form. J.Mol.Biol., 416, 2012
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2N99
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![BU of 2n99 by Molmil](/molmil-images/mine/2n99) | Solution structure of the SLURP-2, a secreted isoform of Lynx1 | 分子名称: | Ly-6/neurotoxin-like protein 1 | 著者 | Paramonov, A.S, Shenkarev, Z.O, Lyukmanova, E.N, Arseniev, A.S. | 登録日 | 2015-11-11 | 公開日 | 2016-09-21 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Secreted Isoform of Human Lynx1 (SLURP-2): Spatial Structure and Pharmacology of Interactions with Different Types of Acetylcholine Receptors. Sci Rep, 6, 2016
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2UX2
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![BU of 2ux2 by Molmil](/molmil-images/mine/2ux2) | High resolution structure of human CD59 | 分子名称: | CD59 GLYCOPROTEIN | 著者 | Leath, K.J, Johnson, S, Roversi, P, Morgan, B.P, Smith, R.A.G, Lea, S.M. | 登録日 | 2007-03-26 | 公開日 | 2007-08-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | High-Resolution Structures of Bacterially Expressed Soluble Human Cd59. Acta Crystallogr.,Sect.F, 63, 2007
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2UWR
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![BU of 2uwr by Molmil](/molmil-images/mine/2uwr) | High resolution structure of human CD59 | 分子名称: | CD59 GLYCOPROTEIN | 著者 | Leath, K.J, Johnson, S, Roversi, P, Morgan, B.P, Smith, R.A.G, Lea, S.M. | 登録日 | 2007-03-23 | 公開日 | 2007-08-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | 主引用文献 | High-Resolution Structures of Bacterially Expressed Soluble Human Cd59. Acta Crystallogr.,Sect.F, 63, 2007
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2OFS
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![BU of 2ofs by Molmil](/molmil-images/mine/2ofs) | Crystal structure of human CD59 | 分子名称: | CD59 glycoprotein | 著者 | Davies, C. | 登録日 | 2007-01-04 | 公開日 | 2007-05-29 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Crystal structure of CD59: implications for molecular recognition of the complement proteins C8 and C9 in the membrane-attack complex. Acta Crystallogr.,Sect.D, 63, 2007
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6ZZF
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![BU of 6zzf by Molmil](/molmil-images/mine/6zzf) | |
6ZZE
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![BU of 6zze by Molmil](/molmil-images/mine/6zze) | |
1CDR
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![BU of 1cdr by Molmil](/molmil-images/mine/1cdr) | STRUCTURE OF A SOLUBLE, GLYCOSYLATED FORM OF THE HUMAN COMPLEMENT REGULATORY PROTEIN CD59 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CD59 | 著者 | Fletcher, C.M, Harrison, R.A, Lachmann, P.J, Neuhaus, D. | 登録日 | 1994-06-01 | 公開日 | 1994-09-30 | 最終更新日 | 2020-07-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of a soluble, glycosylated form of the human complement regulatory protein CD59. Structure, 2, 1994
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1CDS
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![BU of 1cds by Molmil](/molmil-images/mine/1cds) | STRUCTURE OF A SOLUBLE, GLYCOSYLATED FORM OF THE HUMAN COMPLEMENT REGULATORY PROTEIN CD59 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD59 | 著者 | Fletcher, C.M, Harrison, R.A, Lachmann, P.J, Neuhaus, D. | 登録日 | 1994-06-01 | 公開日 | 1994-09-30 | 最終更新日 | 2020-07-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of a soluble, glycosylated form of the human complement regulatory protein CD59. Structure, 2, 1994
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1CDQ
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![BU of 1cdq by Molmil](/molmil-images/mine/1cdq) | STRUCTURE OF A SOLUBLE, GLYCOSYLATED FORM OF THE HUMAN COMPLEMENT REGULATORY PROTEIN CD59 | 分子名称: | CD59 | 著者 | Fletcher, C.M, Harrison, R.A, Lachmann, P.J, Neuhaus, D. | 登録日 | 1994-06-01 | 公開日 | 1994-09-30 | 最終更新日 | 2022-02-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of a soluble, glycosylated form of the human complement regulatory protein CD59. Structure, 2, 1994
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1ERH
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![BU of 1erh by Molmil](/molmil-images/mine/1erh) | THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE EXTRACELLULAR REGION OF THE COMPLEMENT REGULATORY PROTEIN, CD59, A NEW CELL SURFACE PROTEIN DOMAIN RELATED TO NEUROTOXINS | 分子名称: | CD59 | 著者 | Kieffer, B, Driscoll, P.C, Campbell, I.D, Willis, A.C, Van Der Merwe, P.A, Davis, S.J. | 登録日 | 1993-12-13 | 公開日 | 1994-04-30 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Three-dimensional solution structure of the extracellular region of the complement regulatory protein CD59, a new cell-surface protein domain related to snake venom neurotoxins. Biochemistry, 33, 1994
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1ERG
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![BU of 1erg by Molmil](/molmil-images/mine/1erg) | THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE EXTRACELLULAR REGION OF THE COMPLEMENT REGULATORY PROTEIN, CD59, A NEW CELL SURFACE PROTEIN DOMAIN RELATED TO NEUROTOXINS | 分子名称: | CD59 | 著者 | Kieffer, B, Driscoll, P.C, Campbell, I.D, Willis, A.C, Van Der Merwe, P.A, Davis, S.J. | 登録日 | 1993-12-13 | 公開日 | 1994-04-30 | 最終更新日 | 2022-02-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Three-dimensional solution structure of the extracellular region of the complement regulatory protein CD59, a new cell-surface protein domain related to snake venom neurotoxins. Biochemistry, 33, 1994
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4BIK
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![BU of 4bik by Molmil](/molmil-images/mine/4bik) | Structure of a disulfide locked mutant of Intermedilysin with human CD59 | 分子名称: | CD59 GLYCOPROTEIN, INTERMEDILYSIN | 著者 | Johnson, S, Brooks, N.J, Smith, R.A.G, Lea, S.M, Bubeck, D. | 登録日 | 2013-04-10 | 公開日 | 2013-05-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.494 Å) | 主引用文献 | Structural Basis for Recognition of the Pore- Forming Toxin Intermedilysin by Human Complement Receptor Cd59 Cell Rep., 3, 2013
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3LAQ
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![BU of 3laq by Molmil](/molmil-images/mine/3laq) | Structure-based engineering of species selectivity in the uPA-uPAR interaction | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor, Urokinase-type plasminogen activator | 著者 | Huang, M. | 登録日 | 2010-01-06 | 公開日 | 2010-02-02 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure-based engineering of species selectivity in the interaction between urokinase and its receptor: implication for preclinical cancer therapy. J.Biol.Chem., 285, 2010
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4K24
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![BU of 4k24 by Molmil](/molmil-images/mine/4k24) | Structure of anti-uPAR Fab ATN-658 in complex with uPAR | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor, ... | 著者 | Huang, M.D, Xu, X, Yuan, C. | 登録日 | 2013-04-08 | 公開日 | 2014-02-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | 主引用文献 | Identification of a New Epitope in uPAR as a Target for the Cancer Therapeutic Monoclonal Antibody ATN-658, a Structural Homolog of the uPAR Binding Integrin CD11b ( alpha M) Plos One, 9, 2014
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