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PDB: 253 件

8ETV
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BU of 8etv by Molmil
Class2 of the INO80-Hexasome complex
分子名称: DNA (110-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Wu, H, Munoz, E, Gourdet, M, Cheng, Y.F, Narlikar, G.
登録日2022-10-17
公開日2023-07-12
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility.
Science, 381, 2023
4XUJ
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BU of 4xuj by Molmil
Nucleosome core particle containing adducts from treatment with a thiomorpholine-substituted [(eta-6-p-cymene)Ru(3-hydroxy-2-pyridone)Cl] compound
分子名称: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
著者Adhireksan, Z, Davey, C.A.
登録日2015-01-26
公開日2016-01-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.18 Å)
主引用文献Contrasting Cytotoxicity and Reactivity of RuII-Arene Complexes of Morpholine vs Thiomorpholine Substituted 3-Hydroxy-2-pyridone Ligands
To Be Published
7NKY
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BU of 7nky by Molmil
RNA Polymerase II-Spt4/5-nucleosome-FACT structure
分子名称: Chromatin elongation factor SPT4, DNA (138-MER), DNA (148-MER), ...
著者Farnung, L, Ochmann, M, Engeholm, M, Cramer, P.
登録日2021-02-19
公開日2021-07-07
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of nucleosome transcription mediated by Chd1 and FACT.
Nat.Struct.Mol.Biol., 28, 2021
7YRD
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BU of 7yrd by Molmil
histone methyltransferase
分子名称: DNA (146-MER), Histone H2A.Z, Histone H2B 1.1, ...
著者Li, H, Wang, W.Y.
登録日2022-08-09
公開日2023-08-16
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural insight into H4K20 methylation on H2A.Z-nucleosome by SUV420H1.
Mol.Cell, 83, 2023
7SSA
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BU of 7ssa by Molmil
Cryo-EM structure of pioneer factor Cbf1 bound to the nucleosome
分子名称: Centromere-binding protein 1, DNA (137-MER), Histone H2A.1, ...
著者Eek, P, Tan, S.
登録日2021-11-10
公開日2023-04-05
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Basic helix-loop-helix pioneer factors interact with the histone octamer to invade nucleosomes and generate nucleosome-depleted regions.
Mol.Cell, 83, 2023
8GPN
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BU of 8gpn by Molmil
Human menin in complex with H3K79Me2 nucleosome
分子名称: DNA (177-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Lin, J, Yu, D, Lam, W.H, Dang, S, Zhai, Y, Li, X.D.
登録日2022-08-26
公開日2023-02-15
最終更新日2023-03-01
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Menin "reads" H3K79me2 mark in a nucleosomal context.
Science, 379, 2023
3KXB
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BU of 3kxb by Molmil
Structural characterization of H3K56Q nucleosomes and nucleosomal arrays
分子名称: Histone H2A, Histone H2B 1.1, Histone H3.2, ...
著者Clark, N.J, Lilyestrom, W.G.
登録日2009-12-02
公開日2010-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural characterization of H3K56Q nucleosomes and nucleosomal arrays.
Biochim.Biophys.Acta, 1799, 2010
8G8G
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BU of 8g8g by Molmil
Interaction of H3 tail in LIN28B nucleosome with Oct4
分子名称: Histone H2A, Histone H2B, Histone H3, ...
著者Sinha, K.K, Bilokapic, S, Du, Y, Malik, D, Halic, M.
登録日2023-02-17
公開日2023-03-22
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Histone modifications regulate pioneer transcription factor cooperativity.
Nature, 619, 2023
7XPX
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BU of 7xpx by Molmil
Cryo-EM structure of the histone methyltransferase SET8 bound to H4K20Ecx-nucleosome
分子名称: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
著者Shi, L.X, Zhou, Z.
登録日2022-05-06
公開日2022-06-01
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of nucleosomal H4K20 methylation by methyltransferase SET8.
Faseb J., 36, 2022
6S01
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BU of 6s01 by Molmil
Structure of LEDGF PWWP domain bound H3K36 methylated nucleosome
分子名称: Histone H2A, Histone H2B 1.1, Histone H3, ...
著者Wang, H, Farnung, L, Dienemann, C, Cramer, P.
登録日2019-06-13
公開日2019-12-18
最終更新日2020-01-22
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of H3K36-methylated nucleosome-PWWP complex reveals multivalent cross-gyre binding.
Nat.Struct.Mol.Biol., 27, 2020
8SVF
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BU of 8svf by Molmil
BAP1/ASXL1 bound to the H2AK119Ub Nucleosome
分子名称: DNA/RNA (187-MER), DNA/RNA (327-MER), Histone H2A type 1, ...
著者Thomas, J.F, Valencia-Sanchez, M.I, Armache, K.-J.
登録日2023-05-16
公開日2023-08-30
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of histone H2A lysine 119 deubiquitination by Polycomb repressive deubiquitinase BAP1/ASXL1.
Sci Adv, 9, 2023
7X3X
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BU of 7x3x by Molmil
Cryo-EM structure of N1 nucleosome-RA
分子名称: DNA (146-MER), Histone H2A, Histone H2B 1.1, ...
著者Lifei, L, Kangjing, C, Chen, Z.
登録日2022-03-01
公開日2023-09-20
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of the ISW1a complex bound to the dinucleosome.
Nat.Struct.Mol.Biol., 31, 2024
7K6P
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BU of 7k6p by Molmil
Active state Dot1 bound to the unacetylated H4 nucleosome
分子名称: DNA (146-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Valencia-Sanchez, M.I, De Ioannes, P.E, Miao, W, Truong, D.M, Lee, R, Armache, J.-P, Boeke, J.D, Armache, K.-J.
登録日2020-09-21
公開日2021-02-10
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Regulation of the Dot1 histone H3K79 methyltransferase by histone H4K16 acetylation.
Science, 371, 2021
6KIU
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BU of 6kiu by Molmil
Cryo-EM structure of human MLL1-ubNCP complex (3.2 angstrom)
分子名称: DNA (145-MER), GLUTAMINE, Histone H2A, ...
著者Huang, J, Xue, H, Yao, T.
登録日2019-07-20
公開日2019-09-11
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of nucleosome recognition and modification by MLL methyltransferases.
Nature, 573, 2019
2FJ7
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BU of 2fj7 by Molmil
Crystal structure of Nucleosome Core Particle Containing a Poly (dA.dT) Sequence Element
分子名称: 147 bp DNA containing 16 bp poly dA element, 147 bp DNA containing 16 bp poly dT element, Histone H2B, ...
著者Bao, Y, White, C.L, Luger, K.
登録日2005-12-31
公開日2006-09-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Nucleosome Core Particles Containing a Poly(dA.dT) Sequence Element Exhibit a Locally Distorted DNA Structure.
J.Mol.Biol., 361, 2006
8T3T
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BU of 8t3t by Molmil
Structure of Bre1-nucleosome complex - state3
分子名称: 601 DNA strand 1, 601 DNA strand 2, E3 ubiquitin-protein ligase BRE1, ...
著者Zhao, F, Hicks, C.W, Wolberger, C.
登録日2023-06-07
公開日2023-10-18
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献Mechanism of histone H2B monoubiquitination by Bre1.
Nat.Struct.Mol.Biol., 30, 2023
3O62
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BU of 3o62 by Molmil
Nucleosome core particle modified with a cisplatin 1,3-cis-{Pt(NH3)2}2+-d(GpTpG) intrastrand cross-link
分子名称: Cisplatin, DNA (146-MER), Histone H2A type 1, ...
著者Lippard, S.J, Todd, R.C.
登録日2010-07-28
公開日2011-01-05
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.216 Å)
主引用文献Consequences of Cisplatin binding on nucleosome structure and dynamics.
Chem.Biol., 17, 2010
5XBK
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BU of 5xbk by Molmil
Crystal structure of human Importin4
分子名称: Importin-4, histone H3
著者Song, J.J, Yoon, J.
登録日2017-03-20
公開日2018-02-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.223 Å)
主引用文献Integrative Structural Investigation on the Architecture of Human Importin4_Histone H3/H4_Asf1a Complex and Its Histone H3 Tail Binding
J. Mol. Biol., 430, 2018
8T3W
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BU of 8t3w by Molmil
Structure of Bre1-nucleosome complex - state2
分子名称: 601 DNA strand 1, 601 DNA strand 2, E3 ubiquitin-protein ligase BRE1, ...
著者Zhao, F, Hicks, C.W, Wolberger, C.
登録日2023-06-07
公開日2023-10-18
最終更新日2023-11-22
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Mechanism of histone H2B monoubiquitination by Bre1.
Nat.Struct.Mol.Biol., 30, 2023
4R8P
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BU of 4r8p by Molmil
Crystal structure of the Ring1B/Bmi1/UbcH5c PRC1 ubiquitylation module bound to the nucleosome core particle
分子名称: DNA (147-mer), E3 ubiquitin-protein ligase RING2, Ubiquitin-conjugating enzyme E2 D3, ...
著者McGinty, R.K, Henrici, R.C, Tan, S.
登録日2014-09-02
公開日2014-11-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.2846 Å)
主引用文献Crystal structure of the PRC1 ubiquitylation module bound to the nucleosome.
Nature, 514, 2014
7KTQ
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BU of 7ktq by Molmil
Nucleosome from a dimeric PRC2 bound to a nucleosome
分子名称: 601 DNA (167-MER), Histone H2A, Histone H2B, ...
著者Grau, D.J, Armache, K.J.
登録日2020-11-24
公開日2021-02-03
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction.
Nat Commun, 12, 2021
8A3Y
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BU of 8a3y by Molmil
Structure of mammalian Pol II-DSIF-SPT6-PAF1-TFIIS-hexasome elongation complex
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ...
著者Farnung, L, Ochmann, M, Garg, G, Vos, S.M, Cramer, P.
登録日2022-06-09
公開日2024-07-31
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure of a backtracked hexasomal intermediate of nucleosome transcription.
Mol.Cell, 82, 2022
6OM3
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BU of 6om3 by Molmil
Crystal structure of the Orc1 BAH domain in complex with a nucleosome core particle
分子名称: DNA (146-MER), DNA (147-MER), Histone H2A, ...
著者De Ioannes, P.E, Wang, M, Armache, K.-J.
登録日2019-04-18
公開日2019-07-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure and function of the Orc1 BAH-nucleosome complex.
Nat Commun, 10, 2019
5BS7
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BU of 5bs7 by Molmil
Structure of histone H3/H4 in complex with Spt2
分子名称: Histone H3.2, Histone H4, Protein SPT2 homolog, ...
著者Chen, S, Patel, D.J.
登録日2015-06-01
公開日2015-07-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure-function studies of histone H3/H4 tetramer maintenance during transcription by chaperone Spt2.
Genes Dev., 29, 2015
7EA5
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BU of 7ea5 by Molmil
Yeast Set2 bound to a nucleosome containing oncohistone mutations
分子名称: 601-DNA, Histone H2A, Histone H2B, ...
著者Jing, H, Liu, Y.
登録日2021-03-06
公開日2021-07-14
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structure of SETD2/Set2 methyltransferase bound to a nucleosome containing oncohistone mutations.
Cell Discov, 7, 2021

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件を2024-08-14に公開中

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