3O62
Nucleosome core particle modified with a cisplatin 1,3-cis-{Pt(NH3)2}2+-d(GpTpG) intrastrand cross-link
Summary for 3O62
Entry DOI | 10.2210/pdb3o62/pdb |
Descriptor | Histone H3.2, Histone H4, Histone H2A type 1, ... (7 entities in total) |
Functional Keywords | nucleosome, cisplatin, structural protein-dna complex, structural protein/dna |
Biological source | Xenopus laevis (African clawed frog) More |
Cellular location | Nucleus: P84233 P62799 P06897 P02281 |
Total number of polymer chains | 10 |
Total formula weight | 198407.88 |
Authors | Lippard, S.J.,Todd, R.C. (deposition date: 2010-07-28, release date: 2011-01-05, Last modification date: 2024-02-21) |
Primary citation | Todd, R.C.,Lippard, S.J. Consequences of Cisplatin binding on nucleosome structure and dynamics. Chem.Biol., 17:1334-1343, 2010 Cited by PubMed: 21168769DOI: 10.1016/j.chembiol.2010.10.018 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.216 Å) |
Structure validation
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