3O62

Nucleosome core particle modified with a cisplatin 1,3-cis-{Pt(NH3)2}2+-d(GpTpG) intrastrand cross-link

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E (A, E)	Histone H3.2	polymer	135	15303.9	2	UniProt (P84233) Pfam (PF00125)	Xenopus laevis (African clawed frog)
2	B, F (B, F)	Histone H4	polymer	102	11263.2	2	UniProt (P62799) Pfam (PF15511)	Xenopus laevis (African clawed frog)
3	C, G (C, G)	Histone H2A type 1	polymer	128	13907.2	2	UniProt (P06897) Pfam (PF00125) Pfam (PF16211)	Xenopus laevis (clawed frog common platanna platanna)
4	D, H (D, H)	Histone H2B 1.1	polymer	122	13524.8	2	UniProt (P02281) Pfam (PF00125)	Xenopus laevis (clawed frog common platanna platanna)	H2B1.1
5	I (I)	DNA (146-MER)	polymer	146	44739.7	1
6	J (J)	DNA (146-MER)	polymer	146	45370.0	1
7	K (I)	Cisplatin	non-polymer		300.0	1	Chemie (CPT)

Sequence modifications

A, E: 1 - 135 (UniProt: P84233)

PDB	External Database	Details
Ala 102	Gly 103	conflict

C, G: 1 - 128 (UniProt: P06897)

PDB	External Database	Details
Arg 99	Gly 100	conflict
Ser 123	Ala 124	conflict
-	Ala 127	deletion

D, H: 1 - 122 (UniProt: P02281)

PDB	External Database	Details
Thr 29	Ser 33	conflict

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	198107.8
Non-Polymers*	Number of molecules	1
	Total formula weight	300.0
All*	Total formula weight	198407.9

*Water molecules are not included.