4R8P

Crystal structure of the Ring1B/Bmi1/UbcH5c PRC1 ubiquitylation module bound to the nucleosome core particle

Summary for 4R8P

• Entry DOI: 10.2210/pdb4r8p/pdb
• Descriptor: Histone H3.2, Histone H4, Histone H2A, ... (9 entities in total)
• Functional Keywords: ring domain, arginine anchor, ubiquitin ligase, histone modification enzyme, structural protein-dna complex, structural protein/dna
• Biological source: Xenopus laevis (clawed frog,common platanna,platanna); More
• Cellular location: Nucleus: P84233 P62799 P02281 P35226; Cell membrane ; Peripheral membrane protein : P61077
• Total number of polymer chains: 14
• Total formula weight: 284841.16

Authors

McGinty, R.K.,Henrici, R.C.,Tan, S. (deposition date: 2014-09-02, release date: 2014-11-05, Last modification date: 2023-09-20)

• Primary citation: McGinty, R.K.,Henrici, R.C.,Tan, S.; Crystal structure of the PRC1 ubiquitylation module bound to the nucleosome.; Nature, 514:591-596, 2014; PubMed: 25355358; DOI: 10.1038/nature13890

Experimental method

X-RAY DIFFRACTION (3.2846 Å)