5EGG
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1X23
| Crystal structure of ubch5c | 分子名称: | Ubiquitin-conjugating enzyme E2 D3 | 著者 | Nakanishi, M, Teshima, N, Mizushima, T, Murata, S, Tanaka, K, Yamane, T. | 登録日 | 2005-04-19 | 公開日 | 2005-05-03 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structure of ubch5c To be Published
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4S3O
| PCGF5-RING1B-UbcH5c complex | 分子名称: | E3 ubiquitin-protein ligase RING2, Polycomb group RING finger protein 5, Ubiquitin-conjugating enzyme E2 D3, ... | 著者 | Taherbhoy, A.M, Cochran, A.G. | 登録日 | 2015-03-23 | 公開日 | 2015-07-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | BMI1-RING1B is an autoinhibited RING E3 ubiquitin ligase. Nat Commun, 6, 2015
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8UQA
| Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 12-residue linker | 分子名称: | CHLORIDE ION, E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E, SODIUM ION, ... | 著者 | Hu, Q, Botuyan, M.V, Mer, G. | 登録日 | 2023-10-23 | 公開日 | 2024-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.049 Å) | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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5IFR
| Structure of the stable UBE2D3-UbDha conjugate | 分子名称: | GLYCEROL, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 D3 | 著者 | Pruneda, J.N, Mulder, M.P.C, Witting, K, Ovaa, H, Komander, D. | 登録日 | 2016-02-26 | 公開日 | 2016-05-11 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes. Nat.Chem.Biol., 12, 2016
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8UQ9
| Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 4-residue linker | 分子名称: | CHLORIDE ION, E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E, GLYCEROL, ... | 著者 | Hu, Q, Botuyan, M.V, Mer, G. | 登録日 | 2023-10-23 | 公開日 | 2024-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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8UQ8
| Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 2-residue linker | 分子名称: | CHLORIDE ION, E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E, GLYCEROL, ... | 著者 | Hu, Q, Botuyan, M.V, Mer, G. | 登録日 | 2023-10-23 | 公開日 | 2024-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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3UGB
| UbcH5c~Ubiquitin Conjugate | 分子名称: | GLYCEROL, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 D3 | 著者 | Page, R.C, Pruneda, J.N, Klevit, R.E, Misra, S. | 登録日 | 2011-11-02 | 公開日 | 2012-05-16 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural insights into the conformation and oligomerization of E2~ubiquitin conjugates. Biochemistry, 51, 2012
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8AMS
| Complex of human TRIM2 RING domain, UBCH5C, and Ubiquitin | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, GLYCEROL, Polyubiquitin-C, ... | 著者 | Perez-Borrajero, C, Kotova, I, Murciano, B, Hennig, J. | 登録日 | 2022-08-04 | 公開日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural and biophysical studies of TRIM2 and TRIM3 To Be Published
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8UQB
| Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 20-residue linker (crystallization condition 1) | 分子名称: | CHLORIDE ION, E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E, ZINC ION | 著者 | Hu, Q, Botuyan, M.V, Mer, G. | 登録日 | 2023-10-23 | 公開日 | 2024-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.484 Å) | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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6T7F
| RCR E3 ligase E2-Ubiquitin transthiolation intermediate | 分子名称: | 3,3-bis(sulfanyl)-~{N}-(1~{H}-1,2,3-triazol-4-ylmethyl)propanamide, E3 ubiquitin-protein ligase MYCBP2, Polyubiquitin-C, ... | 著者 | Mabbitt, P.D, Virdee, S. | 登録日 | 2019-10-21 | 公開日 | 2020-08-05 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Structural basis for RING-Cys-Relay E3 ligase activity and its role in axon integrity. Nat.Chem.Biol., 16, 2020
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8UQC
| Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 20-residue linker (crystallization condition 2) | 分子名称: | E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E, ZINC ION | 著者 | Hu, Q, Botuyan, M.V, Mer, G. | 登録日 | 2023-10-23 | 公開日 | 2024-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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3RPG
| Bmi1/Ring1b-UbcH5c complex structure | 分子名称: | E3 ubiquitin-protein ligase RING2, Polycomb complex protein BMI-1, Ubiquitin-conjugating enzyme E2 D3, ... | 著者 | Bentley, M.L, Dong, K.C, Cochran, A.G. | 登録日 | 2011-04-26 | 公開日 | 2011-08-17 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.6485 Å) | 主引用文献 | Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex. Embo J., 30, 2011
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4BVU
| Structure of Shigella effector OspG in complex with host UbcH5c- Ubiquitin conjugate | 分子名称: | PROTEIN KINASE OSPG, UBIQUITIN, UBIQUITIN-CONJUGATING ENZYME E2 D3 | 著者 | Pruneda, J.N, LeTrong, I, Stenkamp, R.E, Klevit, R.E, Brzovic, P.S. | 登録日 | 2013-06-28 | 公開日 | 2014-01-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | E2~Ub Conjugates Regulate the Kinase Activity of Shigella Effector Ospg During Pathogenesis. Embo J., 33, 2014
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6CP0
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3L1Z
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8SMX
| Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (class 2) | 分子名称: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | 著者 | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | 登録日 | 2023-04-26 | 公開日 | 2024-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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8SMY
| Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (class 3) | 分子名称: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | 著者 | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | 登録日 | 2023-04-26 | 公開日 | 2024-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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8SMZ
| Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (Class 4) | 分子名称: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | 著者 | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | 登録日 | 2023-04-26 | 公開日 | 2024-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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8SN0
| Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (class 5) | 分子名称: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | 著者 | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | 登録日 | 2023-04-26 | 公開日 | 2024-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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8UPF
| Cryo-EM structure of the human nucleosome core particle in complex with RNF168-UbcH5c | 分子名称: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | 著者 | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | 登録日 | 2023-10-22 | 公開日 | 2024-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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7LYB
| Cryo-EM structure of the human nucleosome core particle in complex with BRCA1-BARD1-UbcH5c | 分子名称: | BRCA1-associated RING domain protein 1, DNA (146-MER), DNA (147-MER), ... | 著者 | Hu, Q, Botuyan, M.V, Zhao, D, Cui, D, Mer, E, Mer, G. | 登録日 | 2021-03-06 | 公開日 | 2021-07-28 | 最終更新日 | 2021-09-01 | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | 主引用文献 | Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation. Nature, 596, 2021
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4R8P
| Crystal structure of the Ring1B/Bmi1/UbcH5c PRC1 ubiquitylation module bound to the nucleosome core particle | 分子名称: | DNA (147-mer), E3 ubiquitin-protein ligase RING2, Ubiquitin-conjugating enzyme E2 D3, ... | 著者 | McGinty, R.K, Henrici, R.C, Tan, S. | 登録日 | 2014-09-02 | 公開日 | 2014-11-05 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.2846 Å) | 主引用文献 | Crystal structure of the PRC1 ubiquitylation module bound to the nucleosome. Nature, 514, 2014
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8SMW
| Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (class 1) | 分子名称: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | 著者 | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | 登録日 | 2023-04-26 | 公開日 | 2024-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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8SN1
| Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c~Ub (UbcH5c chemically conjugated to histone H2A. No density for Ub.) (class 6) | 分子名称: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | 著者 | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | 登録日 | 2023-04-26 | 公開日 | 2024-01-17 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation. Mol.Cell, 84, 2024
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