1VFL
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![BU of 1vfl by Molmil](/molmil-images/mine/1vfl) | Adenosine deaminase | 分子名称: | Adenosine deaminase, ZINC ION | 著者 | Kinoshita, T. | 登録日 | 2004-04-16 | 公開日 | 2005-08-16 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Basis of Compound Recognition by Adenosine Deaminase Biochemistry, 44, 2005
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1NDZ
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![BU of 1ndz by Molmil](/molmil-images/mine/1ndz) | Crystal Structure of Adenosine Deaminase Complexed with FR235999 | 分子名称: | 1-((1R)-1-(HYDROXYMETHYL)-3-(6-((3-(1-METHYL-1H-BENZIMIDAZOL-2-YL)PROPANOYL)AMINO)-1H-INDOL-1-YL)PROPYL)-1H-IMIDAZOLE-4-CARBOXAMIDE, Adenosine Deaminase, ZINC ION | 著者 | Kinoshita, T. | 登録日 | 2002-12-09 | 公開日 | 2003-12-09 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A highly potent non-nucleoside adenosine deaminase inhibitor: efficient drug discovery by intentional lead hybridization J.Am.Chem.Soc., 126, 2004
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1NDW
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![BU of 1ndw by Molmil](/molmil-images/mine/1ndw) | Crystal Structure of Adenosine Deaminase Complexed with FR221647 | 分子名称: | 1-((1R)-1-(HYDROXYMETHYL)-3-PHENYLPROPYL)-1H-IMIDAZOLE-4-CARBOXAMIDE, Adenosine Deaminase, ZINC ION | 著者 | Kinoshita, T. | 登録日 | 2002-12-09 | 公開日 | 2003-12-09 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A highly potent non-nucleoside adenosine deaminase inhibitor: efficient drug discovery by intentional lead hybridization J.Am.Chem.Soc., 126, 2004
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1NDY
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![BU of 1ndy by Molmil](/molmil-images/mine/1ndy) | Crystal Structure of Adenosine Deaminase Complexed with FR230513 | 分子名称: | 1-((1R)-1-(HYDROXYMETHYL)-3-(1-NAPHTHYL)PROPYL)-1H-IMIDAZOLE-4-CARBOXAMIDE, Adenosine Deaminase, ZINC ION | 著者 | Kinoshita, T. | 登録日 | 2002-12-09 | 公開日 | 2003-12-09 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A highly potent non-nucleoside adenosine deaminase inhibitor: efficient drug discovery by intentional lead hybridization J.Am.Chem.Soc., 126, 2004
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1QXL
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![BU of 1qxl by Molmil](/molmil-images/mine/1qxl) | Crystal structure of Adenosine deaminase complexed with FR235380 | 分子名称: | 1-((1R)-1-(HYDROXYMETHYL)-3-{6-[(5-PHENYLPENTANOYL)AMINO]-1H-INDOL-1-YL}PROPYL)-1H-IMIDAZOLE-4-CARBOXAMIDE, Adenosine deaminase, ZINC ION | 著者 | Kinoshita, T. | 登録日 | 2003-09-08 | 公開日 | 2004-09-21 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structure-based design, synthesis, and structure-activity relationship studies of novel non-nucleoside adenosine deaminase inhibitors J.Med.Chem., 47, 2004
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1NDV
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![BU of 1ndv by Molmil](/molmil-images/mine/1ndv) | Crystal Structure of Adenosine Deaminase complexed with FR117016 | 分子名称: | Adenosine deaminase, N''-(4-(5-((1H-BENZIMIDAZOL-2-YLAMINO)METHYL)-2-THIENYL)-1,3-THIAZOL-2-YL)GUANIDINE, ZINC ION | 著者 | Kinoshita, T. | 登録日 | 2002-12-09 | 公開日 | 2003-12-09 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A highly potent non-nucleoside adenosine deaminase inhibitor: efficient drug discovery by intentional lead hybridization J.Am.Chem.Soc., 126, 2004
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1O5R
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![BU of 1o5r by Molmil](/molmil-images/mine/1o5r) | Crystal structure of adenosine deaminase complexed with a potent inhibitor | 分子名称: | 1-[(1R)-3-(6-{[(BENZYLAMINO)CARBONYL]AMINO}-1H-INDOL-1-YL)-1-(HYDROXYMETHYL)PROPYL]-1H-IMIDAZOLE-4-CARBOXAMIDE, Adenosine deaminase, ZINC ION | 著者 | Kinoshita, T. | 登録日 | 2003-10-05 | 公開日 | 2004-09-21 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structure-based design, synthesis, and structure-activity relationship studies of novel non-nucleoside adenosine deaminase inhibitors J.Med.Chem., 47, 2004
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1WXY
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![BU of 1wxy by Molmil](/molmil-images/mine/1wxy) | |
1KRM
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![BU of 1krm by Molmil](/molmil-images/mine/1krm) | |
1V7A
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![BU of 1v7a by Molmil](/molmil-images/mine/1v7a) | |
1UML
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![BU of 1uml by Molmil](/molmil-images/mine/1uml) | |
1V79
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![BU of 1v79 by Molmil](/molmil-images/mine/1v79) | Crystal structures of adenosine deaminase complexed with potent inhibitors | 分子名称: | 1-{(1R,2S)-1-[2-(2,3,-DICHLOROPHENYL)ETHYL]-2-HYDROXYPROPYL}-1H-IMIDAZOLE-4-CARBOXAMIDE, Adenosine deaminase, ZINC ION | 著者 | Kinoshita, T. | 登録日 | 2003-12-14 | 公開日 | 2004-12-21 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure-based design and synthesis of non-nucleoside, potent, and orally bioavailable adenosine deaminase inhibitors J.Med.Chem., 47, 2004
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2E1W
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![BU of 2e1w by Molmil](/molmil-images/mine/2e1w) | |
2Z7G
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![BU of 2z7g by Molmil](/molmil-images/mine/2z7g) | |
1WXZ
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![BU of 1wxz by Molmil](/molmil-images/mine/1wxz) | Crystal structure of adenosine deaminase ligated with a potent inhibitor | 分子名称: | 1-((1R,2S)-1-{2-[2-(4-CHLOROPHENYL)-1,3-BENZOXAZOL-7-YL]ETHYL}-2-HYDROXYPROPYL)-1H-IMIDAZOLE-4-CARBOXAMIDE, Adenosine deaminase, ZINC ION | 著者 | Kinoshita, T. | 登録日 | 2005-02-02 | 公開日 | 2005-08-16 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Rational design of non-nucleoside, potent, and orally bioavailable adenosine deaminase inhibitors: predicting enzyme conformational change and metabolism J.Med.Chem., 48, 2005
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1W1I
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![BU of 1w1i by Molmil](/molmil-images/mine/1w1i) | Crystal structure of dipeptidyl peptidase IV (DPPIV or CD26) in complex with adenosine deaminase | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Weihofen, W.A, Liu, J, Reutter, W, Saenger, W, Fan, H. | 登録日 | 2004-06-22 | 公開日 | 2004-09-02 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | 主引用文献 | Crystal structure of CD26/dipeptidyl-peptidase IV in complex with adenosine deaminase reveals a highly amphiphilic interface. J. Biol. Chem., 279, 2004
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2BGN
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![BU of 2bgn by Molmil](/molmil-images/mine/2bgn) | HIV-1 Tat protein derived N-terminal nonapeptide Trp2-Tat(1-9) bound to the active site of Dipeptidyl peptidase IV (CD26) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Weihofen, W.A, Liu, J, Reutter, W, Saenger, W, Fan, H. | 登録日 | 2005-01-03 | 公開日 | 2005-01-27 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Crystal Structures of HIV-1 Tat-Derived Nonapeptides Tat-(1-9) and Trp2-Tat-(1-9) Bound to the Active Site of Dipeptidyl-Peptidase Iv (Cd26) J.Biol.Chem., 280, 2005
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