Crystal structure of adenosine deaminase ligated with a potent inhibitor

Summary for 1WXY

DescriptorAdenosine deaminase, ZINC ION, N-[4,5-BIS(4-HYDROXYPHENYL)-1,3-THIAZOL-2-YL]HEXANAMIDE, ... (4 entities in total)
Functional Keywordsbeta barel, hydrolase
Biological sourceBos taurus (cattle)
Cellular locationCell membrane ; Peripheral membrane protein ; Extracellular side  P56658
Total number of polymer chains1
Total molecular weight40789.56
Kinoshita, T. (deposition date: 2005-02-02, release date: 2005-08-16, Last modification date: 2017-10-11)
Primary citation
Kinoshita, T.,Nakanishi, I.,Terasaka, T.,Kuno, M.,Seki, N.,Warizaya, M.,Matsumura, H.,Inoue, T.,Takano, K.,Adachi, H.,Mori, Y.,Fujii, T.
Structural Basis of Compound Recognition by Adenosine Deaminase
Biochemistry, 44:10562-10569, 2005
PubMed: 16060665 (PDB entries with the same primary citation)
DOI: 10.1021/bi050529e
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers184.3%15.5%0.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1wxy
no rotation
Molmil generated image of 1wxy
rotated about x axis by 90°
Molmil generated image of 1wxy
rotated about y axis by 90°
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