1NDW
Crystal Structure of Adenosine Deaminase Complexed with FR221647
Summary for 1NDW
Entry DOI | 10.2210/pdb1ndw/pdb |
Related | 1NDV 1NDY 1NDZ |
Descriptor | Adenosine Deaminase, ZINC ION, 1-((1R)-1-(HYDROXYMETHYL)-3-PHENYLPROPYL)-1H-IMIDAZOLE-4-CARBOXAMIDE, ... (4 entities in total) |
Functional Keywords | sbdd, tim-barrel, hydrolase |
Biological source | Bos taurus (cattle) |
Cellular location | Cell membrane; Peripheral membrane protein; Extracellular side (By similarity): P56658 |
Total number of polymer chains | 1 |
Total formula weight | 40666.38 |
Authors | Kinoshita, T. (deposition date: 2002-12-09, release date: 2003-12-09, Last modification date: 2024-03-13) |
Primary citation | Terasaka, T.,Kinoshita, T.,Kuno, M.,Nakanishi, I. A highly potent non-nucleoside adenosine deaminase inhibitor: efficient drug discovery by intentional lead hybridization J.Am.Chem.Soc., 126:34-35, 2004 Cited by PubMed: 14709046DOI: 10.1021/ja038606l PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)