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PDB: 9 件

7WR6
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BU of 7wr6 by Molmil
Crystal structure of ADP-riboxanated caspase-4 in complex with Af1521
分子名称: ADP-ribose glycohydrolase AF_1521, Caspase-4, [[(3~{a}~{S},5~{R},6~{R},6~{a}~{R})-2-azanylidene-3-[(4~{R})-4-azanyl-5-oxidanylidene-pentyl]-6-oxidanyl-3~{a},5,6,6~{a}-tetrahydrofuro[2,3-d][1,3]oxazol-5-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate
著者Hou, Y.J, Zeng, H, Shao, F, Ding, J.
登録日2022-01-26
公開日2023-01-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis.
Nat.Struct.Mol.Biol., 30, 2023
7WR1
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BU of 7wr1 by Molmil
P32 of caspase-4 C258A mutant in complex with OspC3 C-terminal ankyrin-repeat domain
分子名称: Caspase-4, OspC3
著者Hou, Y.J, Zeng, H, Shao, F, Ding, J.
登録日2022-01-26
公開日2023-01-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis.
Nat.Struct.Mol.Biol., 30, 2023
6NRY
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BU of 6nry by Molmil
Crystal structure of human caspase-4
分子名称: Caspase-4, GLYCEROL
著者Yang, J, Liu, Z, Shi, W, Xiao, T.S.
登録日2019-01-24
公開日2020-07-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.184 Å)
主引用文献Crystal structure of human caspase-4
To Be Published
7WR4
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BU of 7wr4 by Molmil
Crystal structure of OspC3-calmodulin-caspase-4 complex
分子名称: Calmodulin-1, Caspase-4, OspC3
著者Hou, Y.J, Zeng, H, Shao, F, Ding, J.
登録日2022-01-26
公開日2023-01-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis.
Nat.Struct.Mol.Biol., 30, 2023
7WR0
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BU of 7wr0 by Molmil
P32 of caspase-4 C258A mutant
分子名称: Caspase-4
著者Hou, Y.J, Zeng, H, Shao, F, Ding, J.
登録日2022-01-26
公開日2023-01-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis.
Nat.Struct.Mol.Biol., 30, 2023
7WR5
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BU of 7wr5 by Molmil
Crystal structure of OspC3-calmodulin-caspase-4 complex binding with 2'-aF-NAD+
分子名称: Calmodulin-1, Caspase-4, OspC3, ...
著者Hou, Y.J, Zeng, H, Shao, F, Ding, J.
登録日2022-01-26
公開日2023-01-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis.
Nat.Struct.Mol.Biol., 30, 2023
8J6K
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BU of 8j6k by Molmil
Crystal structure of pro-interleukin-18 and caspase-4 complex
分子名称: Arginine ADP-riboxanase OspC3, Caspase-4 subunit p10, Caspase-4 subunit p20, ...
著者Sun, Q, Hou, Y.J, Ding, J.
登録日2023-04-26
公開日2023-11-29
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.12 Å)
主引用文献Recognition and maturation of IL-18 by caspase-4 noncanonical inflammasome.
Nature, 624, 2023
8SPB
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BU of 8spb by Molmil
Caspase-4/Pro-IL-18 complex
分子名称: Caspase-4 subunit p10, Caspase-4 subunit p20, Interleukin-18
著者Pascal, D, Dong, Y, Wu, H, Jon, K.
登録日2023-05-02
公開日2023-11-22
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural insights into cytokine cleavage by inflammatory caspase-4.
Nature, 624, 2023
6KMZ
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BU of 6kmz by Molmil
caspase-4 P22/P10 C258A in complex with human GSDMD-C domain
分子名称: Caspase-4, Gasdermin-D
著者Ding, J, Sun, Q.
登録日2019-08-01
公開日2020-03-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.61 Å)
主引用文献Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
Cell, 180, 2020

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件を2024-07-17に公開中

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