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PDB: 20 件
2J6L
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BU of 2j6l by Molmil
Structure of aminoadipate-semialdehyde dehydrogenase
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ALDEHYDE DEHYDROGENASE FAMILY 7 MEMBER A1, BROMIDE ION, ...
著者Bunkoczi, G, Guo, K, Debreczeni, J.E, Smee, C, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, von Delft, F, Oppermann, U.
登録日2006-09-29
公開日2006-10-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Aldehyde Dehydrogenase 7A1 (Aldh7A1) is a Novel Enzyme Involved in Cellular Defense Against Hyperosmotic Stress.
J.Biol.Chem., 285, 2010
6O4C
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BU of 6o4c by Molmil
Structure of ALDH7A1 mutant W175A complexed with NAD
分子名称: 1,2-ETHANEDIOL, Alpha-aminoadipic semialdehyde dehydrogenase, CHLORIDE ION, ...
著者Tanner, J.J, Korasick, D.A, Laciak, A.R.
登録日2019-02-28
公開日2019-07-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and biochemical consequences of pyridoxine-dependent epilepsy mutations that target the aldehyde binding site of aldehyde dehydrogenase ALDH7A1.
Febs J., 287, 2020
6O4E
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BU of 6o4e by Molmil
Structure of ALDH7A1 mutant N167S complexed with NAD
分子名称: Alpha-aminoadipic semialdehyde dehydrogenase, HEXAETHYLENE GLYCOL, MAGNESIUM ION, ...
著者Tanner, J.J, Korasick, D.A, Laciak, A.R.
登録日2019-02-28
公開日2019-07-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural and biochemical consequences of pyridoxine-dependent epilepsy mutations that target the aldehyde binding site of aldehyde dehydrogenase ALDH7A1.
Febs J., 287, 2020
6O4I
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BU of 6o4i by Molmil
Structure of ALDH7A1 mutant E399D complexed with alpha-aminoadipate
分子名称: 1,2-ETHANEDIOL, 2-AMINOHEXANEDIOIC ACID, Alpha-aminoadipic semialdehyde dehydrogenase
著者Tanner, J.J, Korasick, D.A, Laciak, A.R.
登録日2019-02-28
公開日2019-11-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural analysis of pathogenic mutations targeting Glu427 of ALDH7A1, the hot spot residue of pyridoxine-dependent epilepsy.
J. Inherit. Metab. Dis., 43, 2020
4ZUL
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BU of 4zul by Molmil
Structure ALDH7A1 complexed with alpha-aminoadipate
分子名称: 2-AMINOHEXANEDIOIC ACID, Alpha-aminoadipic semialdehyde dehydrogenase, TETRAETHYLENE GLYCOL, ...
著者Luo, M, Tanner, J.J.
登録日2015-05-16
公開日2015-08-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Structural Basis of Substrate Recognition by Aldehyde Dehydrogenase 7A1.
Biochemistry, 54, 2015
6O4B
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BU of 6o4b by Molmil
Structure of ALDH7A1 mutant W175G complexed with NAD
分子名称: 1,2-ETHANEDIOL, Alpha-aminoadipic semialdehyde dehydrogenase, CHLORIDE ION, ...
著者Tanner, J.J, Korasick, D.A, Laciak, A.R.
登録日2019-02-28
公開日2019-07-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural and biochemical consequences of pyridoxine-dependent epilepsy mutations that target the aldehyde binding site of aldehyde dehydrogenase ALDH7A1.
Febs J., 287, 2020
6O4L
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BU of 6o4l by Molmil
Structure of ALDH7A1 mutant E399D complexed with NAD
分子名称: 1,2-ETHANEDIOL, Alpha-aminoadipic semialdehyde dehydrogenase, CHLORIDE ION, ...
著者Tanner, J.J, Korasick, D.A, Laciak, A.R.
登録日2019-02-28
公開日2019-11-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural analysis of pathogenic mutations targeting Glu427 of ALDH7A1, the hot spot residue of pyridoxine-dependent epilepsy.
J. Inherit. Metab. Dis., 43, 2020
6O4D
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BU of 6o4d by Molmil
Structure of ALDH7A1 mutant W175A complexed with L-pipecolic acid
分子名称: 1,2-ETHANEDIOL, Alpha-aminoadipic semialdehyde dehydrogenase, DI(HYDROXYETHYL)ETHER, ...
著者Tanner, J.J, Korasick, D.A, Laciak, A.R.
登録日2019-02-28
公開日2019-07-24
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Structural and biochemical consequences of pyridoxine-dependent epilepsy mutations that target the aldehyde binding site of aldehyde dehydrogenase ALDH7A1.
Febs J., 287, 2020
6O4F
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BU of 6o4f by Molmil
Structure of ALDH7A1 mutant N167S complexed with alpha-aminoadipate
分子名称: 1,2-ETHANEDIOL, 2-AMINOHEXANEDIOIC ACID, Alpha-aminoadipic semialdehyde dehydrogenase
著者Tanner, J.J, Korasick, D.A, Laciak, A.R.
登録日2019-02-28
公開日2019-07-24
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and biochemical consequences of pyridoxine-dependent epilepsy mutations that target the aldehyde binding site of aldehyde dehydrogenase ALDH7A1.
Febs J., 287, 2020
4ZVX
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BU of 4zvx by Molmil
Structure of apo human ALDH7A1 in space group P4212
分子名称: Alpha-aminoadipic semialdehyde dehydrogenase
著者Tanner, J.J.
登録日2015-05-18
公開日2015-08-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Basis of Substrate Recognition by Aldehyde Dehydrogenase 7A1.
Biochemistry, 54, 2015
4ZVY
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BU of 4zvy by Molmil
Structure of human ALDH7A1 complexed with NAD+ in space group P4212
分子名称: Alpha-aminoadipic semialdehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Tanner, J.J.
登録日2015-05-18
公開日2015-08-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Basis of Substrate Recognition by Aldehyde Dehydrogenase 7A1.
Biochemistry, 54, 2015
4X0U
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BU of 4x0u by Molmil
Structure ALDH7A1 inactivated by 4-diethylaminobenzaldehyde
分子名称: 4-(diethylamino)benzaldehyde, Alpha-aminoadipic semialdehyde dehydrogenase, MAGNESIUM ION
著者Luo, M, Tanner, J.J.
登録日2014-11-23
公開日2015-01-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Diethylaminobenzaldehyde Is a Covalent, Irreversible Inactivator of ALDH7A1.
Acs Chem.Biol., 10, 2015
4ZUK
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BU of 4zuk by Molmil
Structure ALDH7A1 complexed with NAD+
分子名称: Alpha-aminoadipic semialdehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TETRAETHYLENE GLYCOL
著者Luo, M, Tanner, J.J.
登録日2015-05-16
公開日2015-08-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Structural Basis of Substrate Recognition by Aldehyde Dehydrogenase 7A1.
Biochemistry, 54, 2015
6V0Z
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BU of 6v0z by Molmil
Structure of ALDH7A1 mutant R441C complexed with NAD
分子名称: 1,2-ETHANEDIOL, Alpha-aminoadipic semialdehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Korasick, D.A, Tanner, J.J.
登録日2019-11-19
公開日2020-11-25
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Biochemical, structural, and computational analyses of two new clinically identified missense mutations of ALDH7A1.
Chem.Biol.Interact., 2024
6O4H
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BU of 6o4h by Molmil
Structure of ALDH7A1 mutant A171V complexed with NAD
分子名称: 1,2-ETHANEDIOL, Alpha-aminoadipic semialdehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Tanner, J.J, Korasick, D.A, Laciak, A.R.
登録日2019-02-28
公開日2019-07-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural and biochemical consequences of pyridoxine-dependent epilepsy mutations that target the aldehyde binding site of aldehyde dehydrogenase ALDH7A1.
Febs J., 287, 2020
6O4G
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BU of 6o4g by Molmil
Structure of ALDH7A1 mutant P169S complexed with alpha-aminoadipate
分子名称: 2-AMINOHEXANEDIOIC ACID, Alpha-aminoadipic semialdehyde dehydrogenase
著者Tanner, J.J, Korasick, D.A, Laciak, A.R.
登録日2019-02-28
公開日2019-07-24
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural and biochemical consequences of pyridoxine-dependent epilepsy mutations that target the aldehyde binding site of aldehyde dehydrogenase ALDH7A1.
Febs J., 287, 2020
6O4K
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BU of 6o4k by Molmil
Structure of ALDH7A1 mutant E399Q complexed with NAD
分子名称: 1,2-ETHANEDIOL, Alpha-aminoadipic semialdehyde dehydrogenase, CHLORIDE ION, ...
著者Tanner, J.J, Korasick, D.A, Laciak, A.R.
登録日2019-02-28
公開日2019-11-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Structural analysis of pathogenic mutations targeting Glu427 of ALDH7A1, the hot spot residue of pyridoxine-dependent epilepsy.
J. Inherit. Metab. Dis., 43, 2020
6U2X
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BU of 6u2x by Molmil
Structure of ALDH7A1 mutant E399G complexed with NAD
分子名称: Alpha-aminoadipic semialdehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Tanner, J.J, Korasick, D.A, Laciak, A.R.
登録日2019-08-20
公開日2019-11-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural analysis of pathogenic mutations targeting Glu427 of ALDH7A1, the hot spot residue of pyridoxine-dependent epilepsy.
J. Inherit. Metab. Dis., 43, 2020
4X0T
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BU of 4x0t by Molmil
Structure ALDH7A1 inactivated by 4-diethylaminobenzaldehyde and complexed with NAD+
分子名称: 4-(diethylamino)benzaldehyde, Alpha-aminoadipic semialdehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Luo, M, Tanner, J.J.
登録日2014-11-23
公開日2015-01-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Diethylaminobenzaldehyde Is a Covalent, Irreversible Inactivator of ALDH7A1.
Acs Chem.Biol., 10, 2015
4ZVW
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BU of 4zvw by Molmil
Structure of apo human ALDH7A1 in space group C2
分子名称: Alpha-aminoadipic semialdehyde dehydrogenase
著者Tanner, J.J.
登録日2015-05-18
公開日2015-08-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis of Substrate Recognition by Aldehyde Dehydrogenase 7A1.
Biochemistry, 54, 2015

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件を2024-07-10に公開中

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