4X0U
Structure ALDH7A1 inactivated by 4-diethylaminobenzaldehyde
Summary for 4X0U
| Entry DOI | 10.2210/pdb4x0u/pdb |
| Related | 4X0T |
| Descriptor | Alpha-aminoadipic semialdehyde dehydrogenase, 4-(diethylamino)benzaldehyde, MAGNESIUM ION, ... (4 entities in total) |
| Functional Keywords | aldehyde dehydrogenase, nad, oxidoreductase, lysine catabolism, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
| Biological source | Homo sapiens (Human) |
| Cellular location | Cytoplasm, cytosol . Isoform 1: Mitochondrion : P49419 |
| Total number of polymer chains | 4 |
| Total formula weight | 223214.74 |
| Authors | Luo, M.,Tanner, J.J. (deposition date: 2014-11-23, release date: 2015-01-14, Last modification date: 2023-09-27) |
| Primary citation | Luo, M.,Gates, K.S.,Henzl, M.T.,Tanner, J.J. Diethylaminobenzaldehyde Is a Covalent, Irreversible Inactivator of ALDH7A1. Acs Chem.Biol., 10:693-697, 2015 Cited by PubMed: 25554827DOI: 10.1021/cb500977q PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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