6O4D
Structure of ALDH7A1 mutant W175A complexed with L-pipecolic acid
Summary for 6O4D
| Entry DOI | 10.2210/pdb6o4d/pdb |
| Descriptor | Alpha-aminoadipic semialdehyde dehydrogenase, PYRIDINE-2-CARBOXYLIC ACID, TRIETHYLENE GLYCOL, ... (10 entities in total) |
| Functional Keywords | aldehyde dehydrogenase, nad, oxidoreductase, lysine catabolism |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 8 |
| Total formula weight | 447523.53 |
| Authors | Tanner, J.J.,Korasick, D.A.,Laciak, A.R. (deposition date: 2019-02-28, release date: 2019-07-24, Last modification date: 2023-11-15) |
| Primary citation | Laciak, A.R.,Korasick, D.A.,Wyatt, J.W.,Gates, K.S.,Tanner, J.J. Structural and biochemical consequences of pyridoxine-dependent epilepsy mutations that target the aldehyde binding site of aldehyde dehydrogenase ALDH7A1. Febs J., 287:173-189, 2020 Cited by PubMed: 31302938DOI: 10.1111/febs.14997 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.88 Å) |
Structure validation
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