4YXC
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174L
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196L
| THERMODYNAMIC AND STRUCTURAL COMPENSATION IN "SIZE-SWITCH" CORE-REPACKING VARIANTS OF T4 LYSOZYME | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME | 著者 | Baldwin, E, Xu, J, Hajiseyedjavadi, O, Matthews, B.W. | 登録日 | 1995-11-06 | 公開日 | 1996-03-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Thermodynamic and structural compensation in "size-switch" core repacking variants of bacteriophage T4 lysozyme. J.Mol.Biol., 259, 1996
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4PK0
| CRYSTAL STRUCTURE OF T4 LYSOZYME-PEPTIDE IN COMPLEX WITH TEICOPLANIN-A2-2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-2-deoxy-beta-D-glucopyranose, 8-METHYLNONANOIC ACID, ... | 著者 | Han, S, Le, B.V, Hajare, H, Baxter, R.H.G, Miller, S.J. | 登録日 | 2014-05-13 | 公開日 | 2014-09-10 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | X-ray Crystal Structure of Teicoplanin A2-2 Bound to a Catalytic Peptide Sequence via the Carrier Protein Strategy. J.Org.Chem., 79, 2014
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4IAP
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1JTN
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6ZG4
| Structure of M1-StaR-T4L in complex with HTL0009936 at 2.35A | 分子名称: | Muscarinic acetylcholine receptor M1,Endolysin,Muscarinic acetylcholine receptor M1, OLEIC ACID, PHOSPHATE ION, ... | 著者 | Rucktooa, P, Cooke, R.M. | 登録日 | 2020-06-18 | 公開日 | 2021-10-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | From structure to clinic: Design of a muscarinic M1 receptor agonist with potential to treatment of Alzheimer's disease. Cell, 184, 2021
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8JWY
| Crystal structure of A2AR-T4L in complex with 2-118 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-[2-azanyl-6-[2-oxidanylidene-1-[[6-(2-oxidanylpropan-2-yl)pyridin-2-yl]methyl]pyridin-4-yl]pyrimidin-4-yl]-2-methyl-benzenecarbonitrile, Adenosine receptor A2a,Endolysin, ... | 著者 | Weng, Y, Chen, Y, Xu, Y, Song, G. | 登録日 | 2023-06-29 | 公開日 | 2023-08-16 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | Structural insight into the dual-antagonistic mechanism of AB928 on adenosine A 2 receptors. Sci China Life Sci, 67, 2024
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4PHU
| Crystal structure of Human GPR40 bound to allosteric agonist TAK-875 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DIMETHYL SULFOXIDE, Free fatty acid receptor 1,Lysozyme, ... | 著者 | Srivastava, A, Yano, J.K, Hirozane, Y, Kefala, G, Snell, G, Lane, W, Gruswitz, F, Ivetac, A, Aertgeerts, K, Nguyen, J, Jennings, A, Okada, K. | 登録日 | 2014-05-07 | 公開日 | 2014-07-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.332 Å) | 主引用文献 | High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875. Nature, 513, 2014
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4YXA
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2HUM
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8JWZ
| Crystal structure of A2AR-T4L in complex with AB928 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-[2-azanyl-6-[1-[[6-(2-oxidanylpropan-2-yl)pyridin-2-yl]methyl]-1,2,3-triazol-4-yl]pyrimidin-4-yl]-2-methyl-benzenecarbonitrile, Adenosine receptor A2a,Endolysin, ... | 著者 | Weng, Y, Chen, Y, Xu, Y, Song, G. | 登録日 | 2023-06-29 | 公開日 | 2023-08-16 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | Structural insight into the dual-antagonistic mechanism of AB928 on adenosine A 2 receptors. Sci China Life Sci, 67, 2024
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6XOL
| DCN1 bound to DI-1548 | 分子名称: | Lysozyme, DCN1-like protein 1 chimera, N-{(1S)-1-cyclohexyl-2-[(2-methylpropanoyl)amino]ethyl}-N~2~-propanoyl-3-[6-(propan-2-yl)-1,3-benzothiazol-2-yl]-L-alaninamide | 著者 | Stuckey, J.A. | 登録日 | 2020-07-07 | 公開日 | 2021-06-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Selective inhibition of cullin 3 neddylation through covalent targeting DCN1 protects mice from acetaminophen-induced liver toxicity. Nat Commun, 12, 2021
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8A5X
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2B70
| T4 Lysozyme mutant L99A at ambient pressure | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme | 著者 | Collins, M.D, Quillin, M.L, Matthews, B.W, Gruner, S.M, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2005-10-03 | 公開日 | 2005-11-08 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Cooperative water filling of a nonpolar protein cavity observed by high-pressure crystallography and simulation Proc.Natl.Acad.Sci.Usa, 102, 2005
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2B6Z
| T4 Lysozyme mutant L99A at ambient pressure | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme | 著者 | Collins, M.D, Quillin, M.L, Matthews, B.W, Gruner, S.M. | 登録日 | 2005-10-03 | 公開日 | 2005-11-08 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Cooperative water filling of a nonpolar protein cavity observed by high-pressure crystallography and simulation Proc.Natl.Acad.Sci.Usa, 102, 2005
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2QAR
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6PS2
| XFEL beta2 AR structure by ligand exchange from Timolol to Alprenolol. | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-1-[(1-methylethyl)amino]-3-(2-prop-2-en-1-ylphenoxy)propan-2-ol, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ... | 著者 | Ishchenko, A, Stauch, B, Han, G.W, Batyuk, A, Shiriaeva, A, Li, C, Zatsepin, N.A, Weierstall, U, Liu, W, Nango, E, Nakane, T, Tanaka, R, Tono, K, Joti, Y, Iwata, S, Moraes, I, Gati, C, Cherezov, C. | 登録日 | 2019-07-12 | 公開日 | 2019-11-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Toward G protein-coupled receptor structure-based drug design using X-ray lasers. Iucrj, 6, 2019
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2B6Y
| T4 Lysozyme mutant L99A at ambient pressure | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, Lysozyme | 著者 | Collins, M.D, Quillin, M.L, Matthews, B.W, Gruner, S.M. | 登録日 | 2005-10-03 | 公開日 | 2005-11-08 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Cooperative water filling of a nonpolar protein cavity observed by high-pressure crystallography and simulation Proc.Natl.Acad.Sci.Usa, 102, 2005
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2RH1
| High resolution crystal structure of human B2-adrenergic G protein-coupled receptor. | 分子名称: | (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol, 1,4-BUTANEDIOL, ACETAMIDE, ... | 著者 | Cherezov, V, Rosenbaum, D.M, Hanson, M.A, Rasmussen, S.G.F, Thian, F.S, Kobilka, T.S, Choi, H.J, Kuhn, P, Weis, W.I, Kobilka, B.K, Stevens, R.C, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR) | 登録日 | 2007-10-05 | 公開日 | 2007-10-30 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor. Science, 318, 2007
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1SSY
| Crystal structure of phage T4 lysozyme mutant G28A/I29A/G30A/C54T/C97A | 分子名称: | Lysozyme | 著者 | He, M.M, Baase, W.A, Xiao, H, Heinz, D.W, Matthews, B.W. | 登録日 | 2004-03-24 | 公開日 | 2004-10-19 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Alanine-scanning mutagenesis of the beta-sheet region of phage T4 lysozyme suggests that tertiary context has a dominant effect on beta-sheet formation Protein Sci., 13, 2004
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6K69
| Application of anti-helix antibodies in protein structure determination (9213-3LRH) | 分子名称: | 3LRH intrabody, Engineered T4 lysozyme | 著者 | Lee, J.O, Jin, M.S, Kim, J.W, Kim, S, Lee, H, Cho, G.Y. | 登録日 | 2019-06-01 | 公開日 | 2019-08-14 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | 主引用文献 | Application of antihelix antibodies in protein structure determination. Proc.Natl.Acad.Sci.USA, 116, 2019
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5YQR
| Crystal structure of the PH-like domain of Lam6 | 分子名称: | Endolysin/Membrane-anchored lipid-binding protein LAM6 fusion protein, NONAETHYLENE GLYCOL | 著者 | Tong, J, Im, Y.J. | 登録日 | 2017-11-07 | 公開日 | 2018-01-31 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.402 Å) | 主引用文献 | Structural basis of sterol recognition and nonvesicular transport by lipid transfer proteins anchored at membrane contact sites Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6A73
| Complex structure of CSN2 with IP6 | 分子名称: | COP9 signalosome complex subunit 2,Endolysin, INOSITOL HEXAKISPHOSPHATE, SULFATE ION | 著者 | Liu, L, Li, D, Rao, F, Wang, T. | 登録日 | 2018-07-02 | 公開日 | 2019-07-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.447 Å) | 主引用文献 | Basis for metabolite-dependent Cullin-RING ligase deneddylation by the COP9 signalosome. Proc.Natl.Acad.Sci.USA, 117, 2020
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3SB9
| Cu-mediated Dimer of T4 Lysozyme R76H/R80H by Synthetic Symmetrization | 分子名称: | COPPER (II) ION, FORMIC ACID, Lysozyme | 著者 | Soriaga, A.B, Laganowsky, A, Zhao, M, Sawaya, M.R, Cascio, D, Yeates, T.O. | 登録日 | 2011-06-03 | 公開日 | 2011-09-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci., 20, 2011
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