8JWY

Crystal structure of A2AR-T4L in complex with 2-118

Summary for 8JWY

• Entry DOI: 10.2210/pdb8jwy/pdb
• Descriptor: Adenosine receptor A2a,Endolysin, 3-[2-azanyl-6-[2-oxidanylidene-1-[[6-(2-oxidanylpropan-2-yl)pyridin-2-yl]methyl]pyridin-4-yl]pyrimidin-4-yl]-2-methyl-benzenecarbonitrile, CHOLESTEROL, ... (7 entities in total)
• Functional Keywords: adenosine receptor 2a, gpcr, inhibitor, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 1
• Total formula weight: 60361.95

Authors

Weng, Y.,Chen, Y.,Xu, Y.,Song, G. (deposition date: 2023-06-29, release date: 2023-08-16, Last modification date: 2024-02-21)

• Primary citation: Weng, Y.,Yang, X.,Zhang, Q.,Chen, Y.,Xu, Y.,Zhu, C.,Xie, Q.,Wang, Y.,Yang, H.,Liu, M.,Lu, W.,Song, G.; Structural insight into the dual-antagonistic mechanism of AB928 on adenosine A 2 receptors.; Sci China Life Sci, 2024; PubMed: 38319473; DOI: 10.1007/s11427-023-2459-8

Experimental method

X-RAY DIFFRACTION (2.33 Å)