2RH1

High resolution crystal structure of human B2-adrenergic G protein-coupled receptor.

Summary for 2RH1

Descriptorbeta-2-adrenergic receptor/T4-lysozyme chimera, MALTOSE, SULFATE ION, ... (10 entities in total)
Functional Keywordsgpcr, 7tm, adrenergic, fusion, lipidic cubic phase, lipidic, mesophase, cholesterol, membrane protein, membrane protein - hydrolase complex, structural genomics, psi-2, protein structure initiative, accelerated technologies center for gene to 3d structure, atcg3d, gpcr network, membrane protein / hydrolase
Biological sourceHomo sapiens (human,)
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Cellular locationCell membrane ; Multi- pass membrane protein  P07550
Total number of polymer chains1
Total molecular weight60020.83
Authors
Primary citation
Cherezov, V.,Rosenbaum, D.M.,Hanson, M.A.,Rasmussen, S.G.,Thian, F.S.,Kobilka, T.S.,Choi, H.J.,Kuhn, P.,Weis, W.I.,Kobilka, B.K.,Stevens, R.C.
High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor.
Science, 318:1258-1265, 2007
PubMed: 17962520 (PDB entries with the same primary citation)
DOI: 10.1126/science.1150577
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.4 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliers0.230400.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2rh1
no rotation
Molmil generated image of 2rh1
rotated about x axis by 90°
Molmil generated image of 2rh1
rotated about y axis by 90°
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