6ZMO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zmo by Molmil](/molmil-images/mine/6zmo) | SARS-CoV-2 Nsp1 bound to the human LYAR-80S-eEF1a ribosome complex | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2020-07-03 | 公開日 | 2020-08-19 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
|
|
7WTX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wtx by Molmil](/molmil-images/mine/7wtx) | Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-B1 | 分子名称: | 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | 著者 | Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R. | 登録日 | 2022-02-05 | 公開日 | 2022-10-19 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The nucleoplasmic phase of pre-40S formation prior to nuclear export. Nucleic Acids Res., 50, 2022
|
|
7WTT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wtt by Molmil](/molmil-images/mine/7wtt) | Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A1 (with CK1) | 分子名称: | 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | 著者 | Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R. | 登録日 | 2022-02-05 | 公開日 | 2022-10-19 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The nucleoplasmic phase of pre-40S formation prior to nuclear export. Nucleic Acids Res., 50, 2022
|
|
8XSZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8xsz by Molmil](/molmil-images/mine/8xsz) | Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA and P-tRNA | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | 著者 | Li, X, Wang, M, Cheng, J. | 登録日 | 2024-01-10 | 公開日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
|
|
8XXM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8xxm by Molmil](/molmil-images/mine/8xxm) | Cryo-EM structure of the human 40S ribosome with PDCD4 and eIF3G | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. | 登録日 | 2024-01-18 | 公開日 | 2024-05-01 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation. Cell Res., 34, 2024
|
|
7TQL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7tql by Molmil](/molmil-images/mine/7tql) | CryoEM structure of the human 40S small ribosomal subunit in complex with translation initiation factors eIF1A and eIF5B. | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Lapointe, C.P, Grosely, R, Sokabe, M, Alvarado, C, Wang, J, Montabana, E, Villa, N, Shin, B, Dever, T, Fraser, C, Fernandez, I.S, Puglisi, J.D. | 登録日 | 2022-01-26 | 公開日 | 2022-04-27 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining. Nature, 607, 2022
|
|
8PJ4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8pj4 by Molmil](/molmil-images/mine/8pj4) | Structure of human 48S translation initiation complex after eIF5 release (48S-4) | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Petrychenko, V, Yi, S.-H, Liedtke, D, Peng, B.Z, Rodnina, M.V, Fischer, N. | 登録日 | 2023-06-22 | 公開日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining Nat.Struct.Mol.Biol., 2024
|
|
6ZXD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zxd by Molmil](/molmil-images/mine/6zxd) | Cryo-EM structure of a late human pre-40S ribosomal subunit - State F1 | 分子名称: | 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | 著者 | Ameismeier, M, Zemp, I, van den Heuvel, J, Thoms, M, Berninghausen, O, Kutay, U, Beckmann, R. | 登録日 | 2020-07-29 | 公開日 | 2020-12-02 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for the final steps of human 40S ribosome maturation. Nature, 587, 2020
|
|
6ZN5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zn5 by Molmil](/molmil-images/mine/6zn5) | SARS-CoV-2 Nsp1 bound to a pre-40S-like ribosome complex - state 2 | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2020-07-06 | 公開日 | 2020-07-29 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020
|
|
7WTW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wtw by Molmil](/molmil-images/mine/7wtw) | Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A3 | 分子名称: | 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | 著者 | Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R. | 登録日 | 2022-02-05 | 公開日 | 2022-10-19 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | The nucleoplasmic phase of pre-40S formation prior to nuclear export. Nucleic Acids Res., 50, 2022
|
|
6Y0G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6y0g by Molmil](/molmil-images/mine/6y0g) | Structure of human ribosome in classical-PRE state | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... | 著者 | Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A. | 登録日 | 2020-02-07 | 公開日 | 2020-04-15 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes. Cell Rep, 31, 2020
|
|
7WU0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wu0 by Molmil](/molmil-images/mine/7wu0) | Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-B3 | 分子名称: | 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | 著者 | Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R. | 登録日 | 2022-02-05 | 公開日 | 2022-10-19 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | The nucleoplasmic phase of pre-40S formation prior to nuclear export. Nucleic Acids Res., 50, 2022
|
|
8PJ2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8pj2 by Molmil](/molmil-images/mine/8pj2) | Structure of human 48S translation initiation complex in AUG recognition state after eIF5-induced GTP hydrolysis by eIF2 (48S-2) | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Petrychenko, V, Yi, S.-H, Liedtke, D, Peng, B.Z, Rodnina, M.V, Fischer, N. | 登録日 | 2023-06-22 | 公開日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining Nat.Struct.Mol.Biol., 2024
|
|
6OLG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6olg by Molmil](/molmil-images/mine/6olg) | |
8PJ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8pj1 by Molmil](/molmil-images/mine/8pj1) | Structure of human 48S translation initiation complex in open codon scanning state (48S-1) | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Petrychenko, V, Yi, S.-H, Liedtke, D, Peng, B.Z, Rodnina, M.V, Fischer, N. | 登録日 | 2023-06-22 | 公開日 | 2024-08-14 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis for translational control by the human 48S initiation complex from codon scanning toward subunit joining Nat.Struct.Mol.Biol., 2024
|
|
6OLI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6oli by Molmil](/molmil-images/mine/6oli) | |
7A09
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7a09 by Molmil](/molmil-images/mine/7a09) | Structure of a human ABCE1-bound 43S pre-initiation complex - State III | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Kratzat, H, Mackens-Kiani, T, Ameismeier, A, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2020-08-07 | 公開日 | 2020-10-14 | 最終更新日 | 2021-01-13 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes. Embo J., 40, 2021
|
|
6Y57
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6y57 by Molmil](/molmil-images/mine/6y57) | Structure of human ribosome in hybrid-PRE state | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Bhaskar, V, Schenk, A.D, Cavadini, S, von Loeffelholz, O, Natchiar, S.K, Klaholz, B.P, Chao, J.A. | 登録日 | 2020-02-25 | 公開日 | 2020-04-15 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes. Cell Rep, 31, 2020
|
|
7WTV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7wtv by Molmil](/molmil-images/mine/7wtv) | Cryo-EM structure of a human pre-40S ribosomal subunit - State RRP12-A2 | 分子名称: | 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | 著者 | Cheng, J, Lau, B, Thoms, M, Ameismeier, M, Berninghausen, O, Hurt, E, Beckmann, R. | 登録日 | 2022-02-05 | 公開日 | 2022-10-19 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | The nucleoplasmic phase of pre-40S formation prior to nuclear export. Nucleic Acids Res., 50, 2022
|
|
5AJ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5aj0 by Molmil](/molmil-images/mine/5aj0) | Cryo electron microscopy of actively translating human polysomes (POST state). | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Behrmann, E, Loerke, J, Budkevich, T.V, Yamamoto, K, Schmidt, A, Penczek, P.A, Vos, M.R, Burger, J, Mielke, T, Scheerer, P, Spahn, C.M.T. | 登録日 | 2015-02-19 | 公開日 | 2015-05-20 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural Snapshots of Actively Translating Human Ribosomes Cell(Cambridge,Mass.), 161, 2015
|
|
6G5I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6g5i by Molmil](/molmil-images/mine/6g5i) | Cryo-EM structure of a late human pre-40S ribosomal subunit - State R | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. | 登録日 | 2018-03-29 | 公開日 | 2018-06-06 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
|
|
8OZ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8oz0 by Molmil](/molmil-images/mine/8oz0) | Structure of a human 48S translation initiation complex with eIF4F and eIF4A | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Brito Querido, J, Sokabe, M, Diaz-Lopez, I, Gordiyenko, Y, Fraser, C.S, Ramakrishnan, V. | 登録日 | 2023-05-06 | 公開日 | 2024-02-07 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | The structure of a human translation initiation complex reveals two independent roles for the helicase eIF4A. Nat.Struct.Mol.Biol., 31, 2024
|
|
8XXN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8xxn by Molmil](/molmil-images/mine/8xxn) | Cryo-EM structure of the human 43S ribosome with PDCD4 | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. | 登録日 | 2024-01-18 | 公開日 | 2024-05-01 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation. Cell Res., 34, 2024
|
|
7MQ8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mq8 by Molmil](/molmil-images/mine/7mq8) | Cryo-EM structure of the human SSU processome, state pre-A1 | 分子名称: | 18S rRNA, 40S ribosomal protein S11, 40S ribosomal protein S12, ... | 著者 | Vanden Broeck, A, Singh, S, Klinge, S. | 登録日 | 2021-05-05 | 公開日 | 2021-09-22 | 最終更新日 | 2024-08-28 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Nucleolar maturation of the human small subunit processome. Science, 373, 2021
|
|
5T2C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5t2c by Molmil](/molmil-images/mine/5t2c) | CryoEM structure of the human ribosome at 3.6 Angstrom resolution | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | 著者 | Zhang, X, Lai, M, Zhou, Z.H. | 登録日 | 2016-08-23 | 公開日 | 2017-01-25 | 最終更新日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes. Nat Commun, 7, 2016
|
|