4U4O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4u4o by Molmil](/molmil-images/mine/4u4o) | Crystal structure of Geneticin bound to the yeast 80S ribosome | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | 登録日 | 2014-07-24 | 公開日 | 2014-10-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
|
|
6N8K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n8k by Molmil](/molmil-images/mine/6n8k) | Cryo-EM structure of early cytoplasmic-immediate (ECI) pre-60S ribosomal subunit | 分子名称: | 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | 著者 | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | 登録日 | 2018-11-29 | 公開日 | 2019-03-13 | 最終更新日 | 2020-01-08 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome. Nat Commun, 10, 2019
|
|
6R84
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6r84 by Molmil](/molmil-images/mine/6r84) | Yeast Vms1 (Q295L)-60S ribosomal subunit complex (pre-state with Arb1) | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Su, T, Izawa, T, Cheng, J, Yamashita, Y, Berninghausen, O, Inada, T, Neupert, W, Beckmann, R. | 登録日 | 2019-03-31 | 公開日 | 2019-06-26 | 最終更新日 | 2019-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis. Nature, 570, 2019
|
|
6N8L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n8l by Molmil](/molmil-images/mine/6n8l) | Cryo-EM structure of early cytoplasmic-late (ECL) pre-60S ribosomal subunit | 分子名称: | 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | 著者 | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | 登録日 | 2018-11-29 | 公開日 | 2019-03-13 | 最終更新日 | 2020-01-08 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome. Nat Commun, 10, 2019
|
|
5NDG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ndg by Molmil](/molmil-images/mine/5ndg) | Crystal structure of geneticin (G418) bound to the yeast 80S ribosome | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G. | 登録日 | 2017-03-08 | 公開日 | 2017-12-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Aminoglycoside interactions and impacts on the eukaryotic ribosome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
5NDW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ndw by Molmil](/molmil-images/mine/5ndw) | Crystal structure of aminoglycoside TC007 bound to the yeast 80S ribosome | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G. | 登録日 | 2017-03-09 | 公開日 | 2017-12-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Aminoglycoside interactions and impacts on the eukaryotic ribosome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
8CMJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8cmj by Molmil](/molmil-images/mine/8cmj) | Translocation intermediate 4 (TI-4*) of 80S S. cerevisiae ribosome with eEF2 in the absence of sordarin | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. | 登録日 | 2023-02-20 | 公開日 | 2023-09-20 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.79 Å) | 主引用文献 | mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
|
|
6OIG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6oig by Molmil](/molmil-images/mine/6oig) | Subunit joining exposes nascent pre-40S rRNA for processing and quality control | 分子名称: | 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | 著者 | Rai, J, Parker, M.D, Ghalei, H, Johnson, M.C, Karbstein, K, Stroupe, M.E. | 登録日 | 2019-04-09 | 公開日 | 2020-09-30 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | An open interface in the pre-80S ribosome coordinated by ribosome assembly factors Tsr1 and Dim1 enables temporal regulation of Fap7. Rna, 27, 2021
|
|
6YLY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6yly by Molmil](/molmil-images/mine/6yly) | pre-60S State NE2 (TAP-Flag-Nop53) | 分子名称: | 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ... | 著者 | Kater, L, Beckmann, R. | 登録日 | 2020-04-07 | 公開日 | 2020-07-29 | 最終更新日 | 2020-09-02 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis. Mol.Cell, 79, 2020
|
|
8BQX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8bqx by Molmil](/molmil-images/mine/8bqx) | Yeast 80S ribosome in complex with Map1 (conformation 2) | 分子名称: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | 著者 | Knorr, A.G, Mackens-Kiani, T, Musial, J, Berninghausen, O, Becker, T, Beatrix, B, Beckmann, R. | 登録日 | 2022-11-21 | 公開日 | 2023-03-22 | 最終更新日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | The dynamic architecture of Map1- and NatB-ribosome complexes coordinates the sequential modifications of nascent polypeptide chains. Plos Biol., 21, 2023
|
|
6N8N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n8n by Molmil](/molmil-images/mine/6n8n) | Cryo-EM structure of Lsg1-engaged (LE) pre-60S ribosomal subunit | 分子名称: | 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ... | 著者 | Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W. | 登録日 | 2018-11-29 | 公開日 | 2019-03-13 | 最終更新日 | 2020-01-08 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome. Nat Commun, 10, 2019
|
|
8BJQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8bjq by Molmil](/molmil-images/mine/8bjq) | Structure of a yeast 80S ribosome-bound N-Acetyltransferase B complex | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Knorr, A.G, Mackens-Kiani, T, Musial, J, Berninghausen, O, Becker, T, Beatrix, B, Beckmann, R. | 登録日 | 2022-11-05 | 公開日 | 2023-02-08 | 最終更新日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | The dynamic architecture of Map1- and NatB-ribosome complexes coordinates the sequential modifications of nascent polypeptide chains. Plos Biol., 21, 2023
|
|
7Z34
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7z34 by Molmil](/molmil-images/mine/7z34) | Structure of pre-60S particle bound to DRG1(AFG2). | 分子名称: | 35S pre-ribosomal RNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Prattes, M, Grishkovskaya, I, Bergler, H, Haselbach, D. | 登録日 | 2022-03-01 | 公開日 | 2022-09-21 | 最終更新日 | 2023-07-19 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Visualizing maturation factor extraction from the nascent ribosome by the AAA-ATPase Drg1. Nat.Struct.Mol.Biol., 29, 2022
|
|
5MC6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mc6 by Molmil](/molmil-images/mine/5mc6) | Cryo-EM structure of a native ribosome-Ski2-Ski3-Ski8 complex from S. cerevisiae | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Schmidt, C, Kowalinski, E, Shanmuganathan, V, Defenouillere, Q, Braunger, K, Heuer, A, Pech, M, Namane, A, Berninghausen, O, Fromont-Racine, M, Jacquier, A, Conti, E, Becker, T, Beckmann, R. | 登録日 | 2016-11-09 | 公開日 | 2017-01-18 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | The cryo-EM structure of a ribosome-Ski2-Ski3-Ski8 helicase complex. Science, 354, 2016
|
|
5GAK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5gak by Molmil](/molmil-images/mine/5gak) | Yeast 60S ribosomal subunit with A-site tRNA, P-site tRNA and eIF-5A | 分子名称: | 25S rRNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, 5.8S rRNA, ... | 著者 | Schmidt, C, Becker, T. | 登録日 | 2015-12-09 | 公開日 | 2016-02-24 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.88 Å) | 主引用文献 | Structure of the hypusinylated eukaryotic translation factor eIF-5A bound to the ribosome. Nucleic Acids Res., 44, 2016
|
|
7NRC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7nrc by Molmil](/molmil-images/mine/7nrc) | Structure of the yeast Gcn1 bound to a leading stalled 80S ribosome with Rbg2, Gir2, A- and P-tRNA and eIF5A | 分子名称: | 18S rRNA (1771-MER), 25S rRNA (3184-MER), 40S ribosomal protein S0-A, ... | 著者 | Pochopien, A.A, Beckert, B, Wilson, D.N. | 登録日 | 2021-03-03 | 公開日 | 2021-05-05 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structure of Gcn1 bound to stalled and colliding 80S ribosomes. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
8BQD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8bqd by Molmil](/molmil-images/mine/8bqd) | Yeast 80S ribosome in complex with Map1 (conformation 1) | 分子名称: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | 著者 | Knorr, A.G, Mackens-Kiani, T, Musial, J, Berninghausen, O, Becker, T, Beatrix, B, Beckmann, R. | 登録日 | 2022-11-21 | 公開日 | 2023-03-22 | 最終更新日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | The dynamic architecture of Map1- and NatB-ribosome complexes coordinates the sequential modifications of nascent polypeptide chains. Plos Biol., 21, 2023
|
|
6FT6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ft6 by Molmil](/molmil-images/mine/6ft6) | Structure of the Nop53 pre-60S particle bound to the exosome nuclear cofactors | 分子名称: | 25S ribosomal RNA, 5S ribosomal RNA, 60S ribosomal protein L11-A, ... | 著者 | Schuller, J.M, Falk, S, Conti, E. | 登録日 | 2018-02-20 | 公開日 | 2018-03-28 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structure of the nuclear exosome captured on a maturing preribosome. Science, 360, 2018
|
|
6S05
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6s05 by Molmil](/molmil-images/mine/6s05) | |
6GQB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gqb by Molmil](/molmil-images/mine/6gqb) | Cryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GDP+AlF4/sordarin) | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | 著者 | Pellegrino, S, Yusupov, M, Yusupova, G, Hashem, Y. | 登録日 | 2018-06-07 | 公開日 | 2018-07-11 | 最終更新日 | 2021-08-04 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance. J. Mol. Biol., 430, 2018
|
|
5APN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5apn by Molmil](/molmil-images/mine/5apn) | Structure of the yeast 60S ribosomal subunit in complex with Arx1, Alb1 and N-terminally tagged Rei1 | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Greber, B.J, Gerhardy, S, Leitner, A, Leibundgut, M, Salem, M, Boehringer, D, Leulliot, N, Aebersold, R, Panse, V.G, Ban, V. | 登録日 | 2015-09-17 | 公開日 | 2015-12-16 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.91 Å) | 主引用文献 | Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation. Cell, 164, 2015
|
|
5JUO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5juo by Molmil](/molmil-images/mine/5juo) | Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure I (fully rotated 40S subunit) | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ... | 著者 | Abeyrathne, P, Koh, C.S, Grant, T, Grigorieff, N, Korostelev, A.A. | 登録日 | 2016-05-10 | 公開日 | 2016-10-05 | 最終更新日 | 2019-11-27 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome. Elife, 5, 2016
|
|
6GQV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gqv by Molmil](/molmil-images/mine/6gqv) | Cryo-EM recosntruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GMPPCP) | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Pellegrino, S, Yusupov, M, Yusupova, G, Hashem, Y. | 登録日 | 2018-06-08 | 公開日 | 2018-07-11 | 最終更新日 | 2018-08-08 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance. J. Mol. Biol., 430, 2018
|
|
6T83
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6t83 by Molmil](/molmil-images/mine/6t83) | Structure of yeast disome (di-ribosome) stalled on poly(A) tract. | 分子名称: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | 著者 | Tesina, P, Buschauer, R, Cheng, J, Berninghausen, O, Becker, R, Beckmann, R. | 登録日 | 2019-10-24 | 公開日 | 2019-12-25 | 最終更新日 | 2020-02-12 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts. Embo J., 39, 2020
|
|
5JUU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5juu by Molmil](/molmil-images/mine/5juu) | Saccharomyces cerevisiae 80S ribosome bound with elongation factor eEF2-GDP-sordarin and Taura Syndrome Virus IRES, Structure V (least rotated 40S subunit) | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 5.8S ribosomal RNA, ... | 著者 | Abeyrathne, P, Koh, C.S, Grant, T, Grigorieff, N, Korostelev, A.A. | 登録日 | 2016-05-10 | 公開日 | 2016-10-05 | 最終更新日 | 2019-11-27 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome. Elife, 5, 2016
|
|