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PDB: 284 件

7B5L
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BU of 7b5l by Molmil
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27-UBE2L3~Ub~ARIH1. Transition State 1
分子名称: 5-azanylpentan-2-one, Cullin-1, Cyclin-A2, ...
著者Horn-Ghetko, D, Prabu, J.R, Schulman, B.A.
登録日2020-12-04
公開日2021-02-10
最終更新日2021-03-10
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Nature, 590, 2021
5OHM
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BU of 5ohm by Molmil
K33-specific affimer bound to K33 diUb
分子名称: K33-specific affimer, POLYETHYLENE GLYCOL (N=34), Polyubiquitin-C
著者Michel, M.A, Komander, D.
登録日2017-07-17
公開日2017-10-04
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling.
Mol. Cell, 68, 2017
6TNF
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BU of 6tnf by Molmil
Structure of monoubiquitinated FANCD2 in complex with FANCI and DNA
分子名称: DNA (33-MER), FANCD2, Fanconi anemia complementation group I, ...
著者Alcon, P, Shakeel, S, Passmore, L.A.
登録日2019-12-07
公開日2020-02-19
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献FANCD2-FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair.
Nat.Struct.Mol.Biol., 27, 2020
4DDI
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BU of 4ddi by Molmil
Crystal structure of human OTUB1/UbcH5b~Ub/Ub
分子名称: Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 D2, Ubiquitin thioesterase OTUB1
著者Juang, Y.C, Sanches, M, Sicheri, F.
登録日2012-01-18
公開日2012-02-22
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (3.802 Å)
主引用文献OTUB1 Co-opts Lys48-Linked Ubiquitin Recognition to Suppress E2 Enzyme Function.
Mol.Cell, 45, 2012
6VAF
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BU of 6vaf by Molmil
Structure of mono-ubiquitinated FANCD2 bound to non-ubiquitinated FANCI and to DNA
分子名称: DNA (29-MER), Fanconi anemia group D2 protein, Fanconi anemia, ...
著者Pavletich, N.P.
登録日2019-12-17
公開日2020-03-18
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献DNA clamp function of the monoubiquitinated Fanconi anaemia ID complex.
Nature, 580, 2020
7B5M
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BU of 7b5m by Molmil
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-p27~Ub~ARIH1. Transition State 2
分子名称: Cullin-1, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinases regulatory subunit 1, ...
著者Horn-Ghetko, D, Prabu, J.R, Schulman, B.A.
登録日2020-12-05
公開日2021-02-17
最終更新日2021-03-10
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Nature, 590, 2021
7TV4
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BU of 7tv4 by Molmil
Crystal structure of NEMO CoZi in complex with HOIP NZF1 and linear diubiquitin
分子名称: E3 ubiquitin-protein ligase RNF31, NF-kappa-B essential modulator, Polyubiquitin-C, ...
著者Rahighi, S, Iyer, M, Oveisi, H.
登録日2022-02-03
公開日2022-08-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Structural basis for the simultaneous recognition of NEMO and acceptor ubiquitin by the HOIP NZF1 domain.
Sci Rep, 12, 2022
6WJD
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BU of 6wjd by Molmil
SA-like state of human 26S Proteasome with non-cleavable M1-linked hexaubiquitin and E3 ubiquitin ligase E6AP/UBE3A
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, ...
著者Chen, X, Walters, K.J.
登録日2020-04-13
公開日2020-08-05
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Cryo-EM Reveals Unanchored M1-Ubiquitin Chain Binding at hRpn11 of the 26S Proteasome.
Structure, 28, 2020
5A5B
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BU of 5a5b by Molmil
Structure of the 26S proteasome-Ubp6 complex
分子名称: 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, ...
著者Aufderheide, A, Beck, F, Stengel, F, Hartwig, M, Schweitzer, A, Pfeifer, G, Goldberg, A.L, Sakata, E, Baumeister, W, Foerster, F.
登録日2015-06-17
公開日2015-07-22
最終更新日2017-08-30
実験手法ELECTRON MICROSCOPY (9.5 Å)
主引用文献Structural Characterization of the Interaction of Ubp6 with the 26S Proteasome.
Proc.Natl.Acad.Sci.USA, 112, 2015
1GJZ
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BU of 1gjz by Molmil
Solution structure of a dimeric N-terminal fragment of human ubiquitin
分子名称: UBIQUITIN
著者Bolton, D, Evans, P.A, Stott, K, Broadhurst, R.W.
登録日2001-08-06
公開日2001-12-13
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure and Properties of a Dimeric N-Terminal Fragment of Human Ubiquitin.
J.Mol.Biol., 314, 2001
2K8C
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BU of 2k8c by Molmil
Solution structure of PLAA family ubiquitin binding domain (PFUC) trans isomer in complex with ubiquitin
分子名称: Phospholipase A-2-activating protein, Ubiquitin
著者Fu, Q.S, Zhou, C.J, Gao, H.C, Lin, D.H, Hu, H.Y.
登録日2008-09-04
公開日2009-05-05
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural Basis for Ubiquitin Recognition by a Novel Domain from Human Phospholipase A2-activating Protein.
J.Biol.Chem., 284, 2009
2K6D
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BU of 2k6d by Molmil
CIN85 Sh3-C domain in complex with ubiquitin
分子名称: SH3 domain-containing kinase-binding protein 1, Ubiquitin
著者Forman-Kay, J, Bezsonova, I.
登録日2008-07-07
公開日2008-08-19
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Interactions between the three CIN85 SH3 domains and ubiquitin: implications for CIN85 ubiquitination.
Biochemistry, 47, 2008
1D3Z
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BU of 1d3z by Molmil
UBIQUITIN NMR STRUCTURE
分子名称: PROTEIN (UBIQUITIN)
著者Cornilescu, G, Marquardt, J.L, Ottiger, M, Bax, A.
登録日1999-10-01
公開日1999-10-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Validation of Protein Structure from Anisotropic Carbonyl Chemical Shifts in a Dilute Liquid Crystalline Phase
J.Am.Chem.Soc., 120, 1998
2KJH
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BU of 2kjh by Molmil
NMR based structural model of the UBCH8-UBIQUITIN complex
分子名称: Ubiquitin, Ubiquitin/ISG15-conjugating enzyme E2 L6
著者Serniwka, S.A, Shaw, G.S.
登録日2009-05-28
公開日2009-12-08
最終更新日2021-10-13
実験手法SOLUTION NMR
主引用文献The structure of the UbcH8-ubiquitin complex shows a unique ubiquitin interaction site.
Biochemistry, 48, 2009
2KDF
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BU of 2kdf by Molmil
NMR structure of minor S5a (196-306):K48 linked diubiquitin species
分子名称: 26S proteasome non-ATPase regulatory subunit 4, Ubiquitin
著者Zhang, N, Wang, Q, Ehlinger, A, Randles, L, Lary, J.W, Kang, Y, Haririnia, A, Cole, J.L, Fushman, D, Walters, K.J.
登録日2009-01-06
公開日2009-09-01
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Structure of the s5a:k48-linked diubiquitin complex and its interactions with rpn13.
Mol.Cell, 35, 2009
2K8B
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BU of 2k8b by Molmil
Solution structure of PLAA family ubiquitin binding domain (PFUC) cis isomer in complex with ubiquitin
分子名称: Phospholipase A-2-activating protein, Ubiquitin
著者Fu, Q.S, Zhou, C.J, Gao, H.C, Lin, D.H, Hu, H.Y.
登録日2008-09-04
公開日2009-05-05
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural Basis for Ubiquitin Recognition by a Novel Domain from Human Phospholipase A2-activating Protein.
J.Biol.Chem., 284, 2009
6N13
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BU of 6n13 by Molmil
UbcH7-Ub Complex with R0RBR Parkin and phosphoubiquitin
分子名称: E3 ubiquitin-protein ligase parkin, Ubiquitin-conjugating enzyme E2 L3, ZINC ION, ...
著者Condos, T.E.C, Dunkerley, K.M, Freeman, E.A, Barber, K.R, Aguirre, J.D, Chaugule, V.K, Xiao, Y, Konermann, L, Walden, H, Shaw, G.S.
登録日2018-11-08
公開日2018-11-28
最終更新日2020-01-08
実験手法SOLUTION NMR
主引用文献Synergistic recruitment of UbcH7~Ub and phosphorylated Ubl domain triggers parkin activation.
EMBO J., 37, 2018
2KX0
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BU of 2kx0 by Molmil
the solution structure of UBB+1, frameshift mutant of ubiquitin B
分子名称: ubiquitin B
著者Ko, S.
登録日2010-04-22
公開日2010-09-08
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献the solution structure of UBB+1, frameshift mutant of ubiquitin B
To be Published
2KLG
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BU of 2klg by Molmil
PERE NMR structure of ubiquitin
分子名称: Ubiquitin
著者Madl, T, Bermel, W, Zangger, K.
登録日2009-07-02
公開日2009-10-06
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Use of Relaxation Enhancements in a Paramagnetic Environment for the Structure Determination of Proteins Using NMR Spectroscopy
Angew.Chem.Int.Ed.Engl., 48, 2009
2KN5
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BU of 2kn5 by Molmil
A Correspondence Between Solution-State Dynamics of an Individual Protein and the Sequence and Conformational Diversity of its Family
分子名称: Ubiquitin
著者Friedland, G.D.
登録日2009-08-14
公開日2009-11-17
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A correspondence between solution-state dynamics of an individual protein and the sequence and conformational diversity of its family.
PLOS COMPUT.BIOL., 5, 2009
2LVO
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BU of 2lvo by Molmil
Structure of the gp78CUE domain bound to monubiquitin
分子名称: E3 ubiquitin-protein ligase AMFR, Ubiquitin
著者Liu, S, Chen, Y, Huang, T, Tarasov, S.G, King, A, Li, J, Weissman, A.M, Byrd, R.A, Das, R.
登録日2012-07-09
公開日2012-11-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Promiscuous Interactions of gp78 E3 Ligase CUE Domain with Polyubiquitin Chains.
Structure, 20, 2012
2LVP
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BU of 2lvp by Molmil
gp78CUE domain bound to the distal ubiquitin of K48-linked diubiquitin
分子名称: E3 ubiquitin-protein ligase AMFR, Ubiquitin
著者Liu, S, Chen, Y, Huang, T, Tarasov, S.G, King, A, Li, J, Weissman, A.M, Byrd, R.A, Das, R.
登録日2012-07-09
公開日2012-11-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Promiscuous Interactions of gp78 E3 Ligase CUE Domain with Polyubiquitin Chains.
Structure, 20, 2012
2RU6
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BU of 2ru6 by Molmil
The pure alternative state of ubiquitin
分子名称: Ubiquitin
著者Kitazawa, S, Kameda, T, Kumo, A, Utsumi, M, Baxter, N, Kato, K, Williamson, M.P, Kitahara, R.
登録日2013-12-04
公開日2014-02-12
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Close Identity between Alternatively Folded State N2 of Ubiquitin and the Conformation of the Protein Bound to the Ubiquitin-Activating Enzyme
Biochemistry, 53, 2014
2FUH
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BU of 2fuh by Molmil
Solution Structure of the UbcH5c/Ub Non-covalent Complex
分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 D3
著者Brzovic, P.S, Lissounov, A, Hoyt, D.W, Klevit, R.E.
登録日2006-01-26
公開日2006-03-28
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献A UbcH5/Ubiquitin Noncovalent Complex Is Required for Processive BRCA1-Directed Ubiquitination.
Mol.Cell, 21, 2006
2LVQ
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BU of 2lvq by Molmil
gp78CUE domain bound to the proximal ubiquitin of K48-linked diubiquitin
分子名称: E3 ubiquitin-protein ligase AMFR, Ubiquitin
著者Liu, S, Chen, Y, Huang, T, Tarasov, S.G, King, A, Li, J, Weissman, A.M, Byrd, R.A, Das, R.
登録日2012-07-09
公開日2012-11-21
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Promiscuous Interactions of gp78 E3 Ligase CUE Domain with Polyubiquitin Chains.
Structure, 20, 2012

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件を2024-08-07に公開中

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