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PDB: 541 件

6KBE
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BU of 6kbe by Molmil
Structure of Deubiquitinase
分子名称: Polyubiquitin-C, Ubiquitin thioesterase
著者Lu, L.N, Liu, L, Wang, F.
登録日2019-06-24
公開日2020-06-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.339 Å)
主引用文献Met1-specific motifs conserved in OTUB subfamily of green plants enable rice OTUB1 to hydrolyse Met1 ubiquitin chains
Nat Commun, 13, 2022
6DGF
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BU of 6dgf by Molmil
Ubiquitin Variant bound to USP2
分子名称: Polyubiquitin-B, SULFATE ION, Ubiquitin carboxyl-terminal hydrolase 2, ...
著者Manczyk, N, Sicheri, F.
登録日2018-05-17
公開日2019-02-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Yeast Two-Hybrid Analysis for Ubiquitin Variant Inhibitors of Human Deubiquitinases.
J. Mol. Biol., 431, 2019
5OHK
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BU of 5ohk by Molmil
Crystal structure of USP30 in covalent complex with ubiquitin propargylamide (high resolution)
分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 30,Ubiquitin carboxyl-terminal hydrolase 30,Ubiquitin carboxyl-terminal hydrolase 30, ZINC ION, ...
著者Gersch, M, Komander, D.
登録日2017-07-17
公開日2017-09-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Mechanism and regulation of the Lys6-selective deubiquitinase USP30.
Nat. Struct. Mol. Biol., 24, 2017
6UMS
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BU of 6ums by Molmil
Crystal structure of MavC in complex with its substrate mimic in C222(1) space group
分子名称: MavC, Ubiquitin, Ubiquitin-conjugating enzyme E2 N
著者Iyer, S, Puvar, K, Das, C.
登録日2019-10-10
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.344 Å)
主引用文献Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination.
Nat Commun, 11, 2020
4DHJ
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BU of 4dhj by Molmil
The structure of a ceOTUB1 ubiquitin aldehyde UBC13~Ub complex
分子名称: Ubiquitin, Ubiquitin aldehyde, Ubiquitin thioesterase otubain-like, ...
著者Wiener, R, Zhang, X, Wang, T, Wolberger, C.
登録日2012-01-27
公開日2012-02-22
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The mechanism of OTUB1-mediated inhibition of ubiquitination.
Nature, 483, 2012
7JXV
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BU of 7jxv by Molmil
ANTH domain of CALM (clathrin-assembly lymphoid myeloid leukemia protein) bound to ubiquitin
分子名称: Phosphatidylinositol-binding clathrin assembly protein, Ubiquitin
著者Pashkova, N, Gakhar, L, Schnicker, N.J, Piper, R.C.
登録日2020-08-28
公開日2021-08-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献ANTH domains within CALM, HIP1R, and Sla2 recognize ubiquitin internalization signals.
Elife, 10, 2021
3OFI
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BU of 3ofi by Molmil
Crystal structure of human insulin-degrading enzyme in complex with ubiquitin
分子名称: 1,4-DIETHYLENE DIOXIDE, Insulin-degrading enzyme, Ubiquitin, ...
著者Kalas, V, Ralat, L.A, Tang, W.-J.
登録日2010-08-15
公開日2010-09-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Ubiquitin is a novel substrate for human insulin-degrading enzyme.
J.Mol.Biol., 406, 2011
4BOS
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BU of 4bos by Molmil
Structure of OTUD2 OTU domain in complex with Ubiquitin K11-linked peptide
分子名称: MAGNESIUM ION, NITRATE ION, OTUD2, ...
著者Mevissen, T.E.T, Hospenthal, M.K, Geurink, P.P, Elliott, P.R, Akutsu, M, Arnaudo, N, Ekkebus, R, Kulathu, Y, Wauer, T, El Oualid, F, Freund, S.M.V, Ovaa, H, Komander, D.
登録日2013-05-22
公開日2013-07-24
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Otu Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis.
Cell(Cambridge,Mass.), 154, 2013
3UGB
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BU of 3ugb by Molmil
UbcH5c~Ubiquitin Conjugate
分子名称: GLYCEROL, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 D3
著者Page, R.C, Pruneda, J.N, Klevit, R.E, Misra, S.
登録日2011-11-02
公開日2012-05-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural insights into the conformation and oligomerization of E2~ubiquitin conjugates.
Biochemistry, 51, 2012
6ASR
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BU of 6asr by Molmil
REV1 UBM2 domain complex with ubiquitin
分子名称: DNA repair protein REV1, NICKEL (II) ION, Ubiquitin
著者Miller, D.J.
登録日2017-08-25
公開日2018-06-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.356 Å)
主引用文献Structures of REV1 UBM2 Domain Complex with Ubiquitin and with a Small-Molecule that Inhibits the REV1 UBM2-Ubiquitin Interaction.
J. Mol. Biol., 430, 2018
5XDP
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BU of 5xdp by Molmil
K11/48-branched teraubiquitin
分子名称: D-ubiquitin, ubiquitin-B
著者Liang, L, Gao, S, Tang, S.
登録日2017-03-28
公開日2017-04-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.376 Å)
主引用文献K11/48-branched teraubiquitin
To Be Published
5ULK
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BU of 5ulk by Molmil
Crystal Structure of RNF165 in complex with a UbcH5b~Ub conjugate
分子名称: E3 ubiquitin-protein ligase RNF165, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2, ...
著者Middleton, A.J, Day, C.L, Wright, J.D.
登録日2017-01-24
公開日2017-06-07
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Discovery of new non-covalent ubiquitin binding sites on UbcH5
To be published
7M4M
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BU of 7m4m by Molmil
Crystal structure of RBR E3 ligase RNF216 with ubiquitin
分子名称: E3 ubiquitin-protein ligase RNF216, GLYCEROL, Ubiquitin, ...
著者Cotton, T.R, Lechtenberg, B.C.
登録日2021-03-21
公開日2022-01-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structural basis of K63-ubiquitin chain formation by the Gordon-Holmes syndrome RBR E3 ubiquitin ligase RNF216.
Mol.Cell, 82, 2022
3AUL
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BU of 3aul by Molmil
Crystal structure of wild-type Lys48-linked diubiquitin in an open conformation
分子名称: Polyubiquitin-C
著者Hirano, T, Olivier, S, Yagi, M, Takemoto, E, Hiromoto, T, Satoh, T, Mizushima, T, Kato, K.
登録日2011-02-09
公開日2011-09-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Conformational dynamics of wild-type Lys48-linked diubiquitin in solution
J.Biol.Chem., 286, 2011
7MYH
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BU of 7myh by Molmil
Ubiquitin variant UbV.k.2 in complex with Ube2k
分子名称: GLYCEROL, Ubiquitin variant UbV.k.2, Ubiquitin-conjugating enzyme E2 K
著者Middleton, A.J, Day, C.L, Teyra, J, Sidhu, S.S.
登録日2021-05-21
公開日2021-08-25
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.394 Å)
主引用文献Identification of Ubiquitin Variants That Inhibit the E2 Ubiquitin Conjugating Enzyme, Ube2k.
Acs Chem.Biol., 16, 2021
4KSK
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BU of 4ksk by Molmil
Gumby/Fam105B in complex with ubiquitin
分子名称: Polyubiquitin-C, Protein FAM105B, SULFATE ION
著者Ceccarelli, D.F, Juang, Y.-C, Sicheri, F.
登録日2013-05-17
公開日2013-06-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis.
Nature, 498, 2013
6A43
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BU of 6a43 by Molmil
R1EN(5-225)-ubiquitin fusion
分子名称: ACETIC ACID, RNA-directed DNA polymerase homolog (R1),Polyubiquitin-C
著者Maita, N.
登録日2018-06-19
公開日2018-10-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure Determination of Ubiquitin by Fusion to a Protein That Forms a Highly Porous Crystal Lattice
J. Am. Chem. Soc., 140, 2018
6A44
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BU of 6a44 by Molmil
R1EN(5-227)-ubiquitin fusion
分子名称: ACETIC ACID, RNA-directed DNA polymerase homolog (R1),Polyubiquitin-C
著者Maita, N.
登録日2018-06-19
公開日2018-10-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure Determination of Ubiquitin by Fusion to a Protein That Forms a Highly Porous Crystal Lattice
J. Am. Chem. Soc., 140, 2018
3IFW
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BU of 3ifw by Molmil
Crystal structure of the S18Y variant of ubiquitin carboxy terminal hydrolase L1 bound to ubiquitin vinylmethylester.
分子名称: METHYL 4-AMINOBUTANOATE, Ubiquitin, Ubiquitin carboxyl-terminal hydrolase isozyme L1
著者Das, C, Boudreaux, D, Maiti, T.
登録日2009-07-26
公開日2010-06-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Ubiquitin vinyl methyl ester binding orients the misaligned active site of the ubiquitin hydrolase UCHL1 into productive conformation.
Proc.Natl.Acad.Sci.USA, 107, 2010
5EYA
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BU of 5eya by Molmil
TRIM25 RING domain in complex with Ubc13-Ub conjugate
分子名称: Polyubiquitin-B, Tripartite motif-containing 25 variant, Ubiquitin-conjugating enzyme E2 N, ...
著者Pornillos, O, Sanchez, J.G.
登録日2015-11-24
公開日2016-08-17
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Mechanism of TRIM25 Catalytic Activation in the Antiviral RIG-I Pathway.
Cell Rep, 16, 2016
1TBE
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BU of 1tbe by Molmil
STRUCTURE OF TETRAUBIQUITIN SHOWS HOW MULTIUBIQUITIN CHAINS CAN BE FORMED
分子名称: TETRAUBIQUITIN
著者Cook, W.J, Jeffrey, L.C, Kasperek, E, Pickart, C.M.
登録日1993-10-14
公開日1994-01-31
最終更新日2019-08-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of tetraubiquitin shows how multiubiquitin chains can be formed.
J.Mol.Biol., 236, 1994
7OJX
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BU of 7ojx by Molmil
E2 UBE2K covalently linked to donor Ub, acceptor di-Ub, and RING E3 primed for K48-linked Ub chain synthesis
分子名称: 1,1'-ethane-1,2-diylbis(1H-pyrrole-2,5-dione), E3 ubiquitin-protein ligase RNF38, Polyubiquitin-B, ...
著者Majorek, K.A, Nakasone, M.A, Huang, D.T.
登録日2021-05-17
公開日2022-01-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of UBE2K-Ub/E3/polyUb reveals mechanisms of K48-linked Ub chain extension.
Nat.Chem.Biol., 18, 2022
8AMS
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BU of 8ams by Molmil
Complex of human TRIM2 RING domain, UBCH5C, and Ubiquitin
分子名称: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, GLYCEROL, Polyubiquitin-C, ...
著者Perez-Borrajero, C, Kotova, I, Murciano, B, Hennig, J.
登録日2022-08-04
公開日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and biophysical studies of TRIM2 and TRIM3
To Be Published
9B0Z
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BU of 9b0z by Molmil
Structure of Optineurin bound to HOIP NZF1 domain and M1-linked diubiquitin, crystal form 2
分子名称: E3 ubiquitin-protein ligase RNF31, Optineurin, Ubiquitin, ...
著者Michel, M.A, Scutts, S, Komander, D.
登録日2024-03-12
公開日2024-07-31
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Linkage and substrate specificity conferred by NZF ubiquitin binding domains
To Be Published
3U30
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BU of 3u30 by Molmil
Crystal structure of a linear-specific Ubiquitin fab bound to linear ubiquitin
分子名称: Heavy chain Fab, Light chain Fab, linear di-ubiquitin
著者Matsumoto, M.L, Dong, K.C, Yu, C, Phu, L, Gao, X, Hannoush, R.N, Hymowitz, S.G, Kirkpatrick, D.S, Dixit, V.M, Kelley, R.F.
登録日2011-10-04
公開日2012-01-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.428 Å)
主引用文献Engineering and structural characterization of a linear polyubiquitin-specific antibody.
J.Mol.Biol., 418, 2012

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件を2024-08-14に公開中

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