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PDB: 534 件
2J7Q
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BU of 2j7q by Molmil
Crystal structure of the ubiquitin-specific protease encoded by murine cytomegalovirus tegument protein M48 in complex with a ubquitin-based suicide substrate
分子名称: GLYCEROL, MAGNESIUM ION, MCMV TEGUMENT PROTEIN M48 ENCODED UBIQUITIN- SPECIFIC PROTEASE, ...
著者Schlieker, C, Weihofen, W.A, Frijns, E, Kattenhorn, L.M, Gaudet, R, Ploegh, H.L.
登録日2006-10-16
公開日2007-03-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of a Herpesvirus-Encoded Cysteine Protease Reveals a Unique Class of Deubiquitinating Enzymes
Mol.Cell, 25, 2007
6GLC
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BU of 6glc by Molmil
Structure of phospho-Parkin bound to phospho-ubiquitin
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, E3 ubiquitin-protein ligase parkin, GLYCEROL, ...
著者Gladkova, C, Maslen, S.L, Skehel, J.M, Komander, D.
登録日2018-05-23
公開日2018-06-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Mechanism of parkin activation by PINK1.
Nature, 559, 2018
3K9O
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BU of 3k9o by Molmil
The crystal structure of E2-25K and UBB+1 complex
分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 K
著者Kang, G.B, Ko, S, Song, S.M, Lee, W, Eom, S.H.
登録日2009-10-16
公開日2010-09-08
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis of E2-25K/UBB+1 Interaction for Neurotoxicity of Alzheimer Disease by Proteasome Inhibition
To be Published
5ULF
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BU of 5ulf by Molmil
Crystal Structure of a UbcH5b~Ub conjugate
分子名称: GLYCEROL, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2
著者Middleton, A.J, Day, C.L, Wright, J.D.
登録日2017-01-24
公開日2017-06-07
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Discovery of new non-covalent ubiquitin binding sites on UbcH5
To be published
3ONS
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BU of 3ons by Molmil
Crystal structure of Human Ubiquitin in a new crystal form
分子名称: Ubiquitin
著者Amodeo, G.A, Huang, K.Y, Mcdermott, A.E, Tong, L.
登録日2010-08-30
公開日2011-02-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The structure of human ubiquitin in 2-methyl-2,4-pentanediol: a new conformational switch.
Protein Sci., 20, 2011
1UBI
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BU of 1ubi by Molmil
SYNTHETIC STRUCTURAL AND BIOLOGICAL STUDIES OF THE UBIQUITIN SYSTEM. PART 1
分子名称: UBIQUITIN
著者Alexeev, D, Bury, S.M, Turner, M.A, Ogunjobi, O.M, Muir, T.W, Ramage, R, Sawyer, L.
登録日1994-02-03
公開日1994-05-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Synthetic, structural and biological studies of the ubiquitin system: the total chemical synthesis of ubiquitin.
Biochem.J., 299, 1994
1UBQ
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BU of 1ubq by Molmil
STRUCTURE OF UBIQUITIN REFINED AT 1.8 ANGSTROMS RESOLUTION
分子名称: UBIQUITIN
著者Vijay-Kumar, S, Bugg, C.E, Cook, W.J.
登録日1987-01-02
公開日1987-04-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of ubiquitin refined at 1.8 A resolution.
J.Mol.Biol., 194, 1987
5GO7
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BU of 5go7 by Molmil
Linear tri-ubiquitin
分子名称: D-ubiquitin, Ubiquitin
著者Gao, S, Pan, M, Zheng, Y.
登録日2016-07-26
公開日2016-11-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献Monomer/Oligomer Quasi-Racemic Protein Crystallography
J.Am.Chem.Soc., 138, 2016
4ZQS
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BU of 4zqs by Molmil
New compact conformation of linear Ub2 structure
分子名称: ubiquitin
著者Thach, T.T, Shin, D, Han, S, Lee, S.
登録日2015-05-11
公開日2016-04-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.804 Å)
主引用文献New conformations of linear polyubiquitin chains from crystallographic and solution-scattering studies expand the conformational space of polyubiquitin.
Acta Crystallogr D Struct Biol, 72, 2016
3EHV
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BU of 3ehv by Molmil
X-ray structure of human ubiquitin Zn(II) adduct
分子名称: Ubiquitin, ZINC ION
著者Falini, G, Fermani, S, Tosi, G.
登録日2008-09-15
公開日2009-03-17
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Structural probing of Zn(II), Cd(II) and Hg(II) binding to human ubiquitin.
Chem.Commun.(Camb.), 45, 2008
5X3M
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BU of 5x3m by Molmil
crystal structure of p-Ub-S65-NH2
分子名称: D-ubiquitin, Polyubiquitin-B
著者Man, P, Shuai, G, Qian, Q, Lei, L.
登録日2017-02-06
公開日2017-04-05
最終更新日2022-02-09
実験手法X-RAY DIFFRACTION (1.818 Å)
主引用文献Structure of p-Ub-S65-NH2 at 1.82 Angstroms resolution
To Be Published
7AHZ
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BU of 7ahz by Molmil
Crystal structure of Western clawed frog MDM2 RING domain homodimer bound to UbcH5B-Ub
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, Polyubiquitin-B, ...
著者Magnussen, H.M, Huang, D.T.
登録日2020-09-25
公開日2021-01-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Identification of a Catalytic Active but Non-Aggregating MDM2 RING Domain Variant.
J.Mol.Biol., 433, 2021
6W9R
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BU of 6w9r by Molmil
Crystal structure of an OTU deubiquitinase from Wolbachia pipientis wMel bound to ubiquitin
分子名称: CITRATE ANION, OTU domain-containing protein wMelOTU, Ubiquitin
著者Schubert, A.F, Pruneda, J.N, Komander, D.
登録日2020-03-23
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Identification and characterization of diverse OTU deubiquitinases in bacteria.
Embo J., 39, 2020
3EFU
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BU of 3efu by Molmil
X-ray structure of human ubiquitin-Hg(II) adduct
分子名称: MERCURY (II) ION, Ubiquitin
著者Falini, G, Fermani, S, Tosi, G.
登録日2008-09-10
公開日2008-12-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Structural probing of Zn(ii), Cd(ii) and Hg(ii) binding to human ubiquitin.
Chem.Commun.(Camb.), 45, 2008
5GOK
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BU of 5gok by Molmil
K11/K63-branched tri-Ubiquitin
分子名称: D-ubiquitin, Ubiquitin
著者Gao, S, Pan, M, Zheng, Y, Liu, L.
登録日2016-07-27
公開日2016-11-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Monomer/Oligomer Quasi-Racemic Protein Crystallography
J.Am.Chem.Soc., 138, 2016
5TXK
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BU of 5txk by Molmil
CRYSTAL STRUCTURE OF USP35 C450S IN COMPLEX WITH UBIQUITIN
分子名称: 1,2-ETHANEDIOL, Polyubiquitin-B, SULFATE ION, ...
著者Bader, G, Weiss-Puxbaum, A, Zoephel, A.
登録日2016-11-17
公開日2018-05-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Expansion of DUB functionality generated by alternative isoforms - USP35, a case study.
J. Cell. Sci., 131, 2018
5L8H
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BU of 5l8h by Molmil
Structure of USP46-UbVME
分子名称: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 46, ZINC ION
著者Clerici, M, Sixma, T, Dharadhar, S.
登録日2016-06-07
公開日2016-09-28
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A conserved two-step binding for the UAF1 regulator to the USP12 deubiquitinating enzyme.
J.Struct.Biol., 196, 2016
8EFX
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BU of 8efx by Molmil
Structure of OtDUB DUB Domain disulfide crosslinked with Ubiquitin
分子名称: OtDUB, Ubiquitin
著者Negron Teron, K.N, Das, C.
登録日2022-09-09
公開日2023-09-20
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Cocrystallization of ubiquitin-deubiquitinase complexes through disulfide linkage.
Acta Crystallogr D Struct Biol, 79, 2023
8F1F
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BU of 8f1f by Molmil
Structure of K48-linked tri-ubiquitin in complex with cyclic peptide
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Non-proteinogenic cyclic peptide (inhibitor), ...
著者Lubkowski, J, Fushman, D, Lemma, B.
登録日2022-11-05
公開日2023-11-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Mechanism of selective recognition of Lys48-linked polyubiquitin by macrocyclic peptide inhibitors of proteasomal degradation.
Nat Commun, 14, 2023
6B7O
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BU of 6b7o by Molmil
Crystal structure of Legionella effector sdeD (lpg2509) H67A in complex with ADP-ribosylated Ubiquitin
分子名称: Polyubiquitin-C, SdeD (lpg2509) H67A, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE
著者Mao, Y, Akturk, A, Wasilko, J.
登録日2017-10-04
公開日2018-04-18
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Mechanism of phosphoribosyl-ubiquitination mediated by a single Legionella effector.
Nature, 557, 2018
5AF4
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BU of 5af4 by Molmil
Structure of Lys33-linked diUb
分子名称: GLYCEROL, SULFATE ION, UBIQUITIN
著者Michel, M.A, Elliott, P.R, Swatek, K.N, Simicek, M, Pruneda, J.N, Wagstaff, J.L, Freund, S.M.V, Komander, D.
登録日2015-01-19
公開日2015-03-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Assembly and Specific Recognition of K29- and K33-Linked Polyubiquitin.
Mol.Cell, 58, 2015
3ALB
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BU of 3alb by Molmil
Cyclic Lys48-linked tetraubiquitin
分子名称: SULFATE ION, ubiquitin
著者Satoh, T, Sakata, E, Yamamoto, S, Yamaguchi, Y, Sumiyoshi, A, Wakatsuki, S, Kato, K.
登録日2010-07-29
公開日2010-08-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of cyclic Lys48-linked tetraubiquitin
Biochem.Biophys.Res.Commun., 2010
5WFI
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BU of 5wfi by Molmil
X-ray structure of MHV PLP2 (Cys1716Ser) catalytic mutant in complex with free ubiquitin
分子名称: FORMIC ACID, GLYCEROL, Ubiquitin, ...
著者Mesecar, A.D, Chen, Y.
登録日2017-07-12
公開日2018-08-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.851 Å)
主引用文献X-ray structure of MHV PLP2 (Cys1716Ser) catalytic mutant in complex with free ubiquitin
To Be Published
8A67
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BU of 8a67 by Molmil
Branched Lys48- and Lys63-linked tri-ubiquitin (K48-K63-Ub3) in complex with matured synthetic nanobody NbSL3.3Q (3rd generation)
分子名称: CHLORIDE ION, GLYCEROL, ISOPROPYL ALCOHOL, ...
著者Lange, S.M, Kulathu, Y.
登録日2022-06-16
公開日2023-02-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Comprehensive approach to study branched ubiquitin chains reveals roles for K48-K63 branches in VCP/p97-related processes
Biorxiv, 2023
6ISU
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BU of 6isu by Molmil
Crystal structure of Lys27-linked di-ubiquitin in complex with its selective interacting protein UCHL3
分子名称: Ubiquitin, Ubiquitin carboxyl-terminal hydrolase isozyme L3
著者Ding, S, Pan, M, Zheng, Q, Ren, Y, Hong, D.
登録日2018-11-19
公開日2019-02-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.866 Å)
主引用文献Chemical Protein Synthesis Enabled Mechanistic Studies on the Molecular Recognition of K27-linked Ubiquitin Chains.
Angew. Chem. Int. Ed. Engl., 58, 2019

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