6X4Y
| Mfd-bound E.coli RNA polymerase elongation complex - IV state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (64-MER), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Llewellyn, E, Chen, J, Kang, J.Y, Darst, S.A. | 登録日 | 2020-05-24 | 公開日 | 2021-02-03 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural basis for transcription complex disruption by the Mfd translocase. Elife, 10, 2021
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6X43
| Mfd-bound E.coli RNA polymerase elongation complex - II state | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA (64-MER), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Llewellyn, E, Chen, J, Kang, J.Y, Darst, S.A. | 登録日 | 2020-05-22 | 公開日 | 2021-02-03 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural basis for transcription complex disruption by the Mfd translocase. Elife, 10, 2021
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5IPL
| SigmaS-transcription initiation complex with 4-nt nascent RNA | 分子名称: | DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Liu, B, Zuo, Y, Steitz, T.A. | 登録日 | 2016-03-09 | 公開日 | 2016-03-30 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Structures of E. coli sigma S-transcription initiation complexes provide new insights into polymerase mechanism. Proc.Natl.Acad.Sci.USA, 113, 2016
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6FLQ
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6BYU
| X-ray crystal structure of Escherichia coli RNA polymerase (RpoB-H526Y) and ppApp complex | 分子名称: | (5R)-5-(6-amino-9H-purin-9-yl)-2-({[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}methyl)-4-oxo-4,5-dihydrofuran-3-yl trihydrogen diphosphate, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Murakami, K.S, Molodtsov, V. | 登録日 | 2017-12-21 | 公開日 | 2018-01-17 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Structure-function comparisons of (p)ppApp vs (p)ppGpp for Escherichia coli RNA polymerase binding sites and for rrnB P1 promoter regulatory responses in vitro. Biochim. Biophys. Acta, 1861, 2018
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7XUI
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7KHI
| Escherichia coli RNA polymerase and rrnBP1 promoter complex with DksA/ppGpp | 分子名称: | CHAPSO, DNA (28-MER), DNA (36-MER), ... | 著者 | Shin, Y, Qayyum, M.Z, Murakami, K.S. | 登録日 | 2020-10-21 | 公開日 | 2020-10-28 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | 主引用文献 | Structural basis of ribosomal RNA transcription regulation. Nat Commun, 12, 2021
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7C97
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6N60
| Escherichia coli RNA polymerase sigma70-holoenzyme bound to upstream fork promoter DNA and Microcin J25 (MccJ25) | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Braffman, N, Hauver, J, Campbell, E.A, Darst, S.A. | 登録日 | 2018-11-23 | 公開日 | 2019-01-09 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.68 Å) | 主引用文献 | Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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7DY6
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4KN7
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6LDI
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6N57
| Cryo-EM structure of Escherichia coli RNAP polymerase bound with TraR in conformation I | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | 登録日 | 2018-11-21 | 公開日 | 2020-02-26 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation. Elife, 8, 2019
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6PSW
| Escherichia coli RNA polymerase promoter unwinding intermediate (TRPo) with TraR and rpsT P2 promoter | 分子名称: | CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | 登録日 | 2019-07-13 | 公開日 | 2020-03-25 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
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8EHA
| Cryo-EM structure of his-elemental paused elongation complex with a folded TL and a rotated RH-FL (out) | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A. | 登録日 | 2022-09-14 | 公開日 | 2023-03-01 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options. Proc.Natl.Acad.Sci.USA, 120, 2023
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6GOV
| Structure of THE RNA POLYMERASE LAMBDA-BASED ANTITERMINATION COMPLEX | 分子名称: | 30S ribosomal protein S10, Antitermination protein N, DNA (I), ... | 著者 | Loll, B, Krupp, F, Said, N, Huang, Y, Buerger, J, Mielke, T, Spahn, C.M.T, Wahl, M.C. | 登録日 | 2018-06-04 | 公開日 | 2019-02-13 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural Basis for the Action of an All-Purpose Transcription Anti-termination Factor. Mol.Cell, 74, 2019
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6GFW
| Cryo-EM structure of bacterial RNA polymerase-sigma54 holoenzyme initial transcribing complex | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Glyde, R, Ye, F.Z, Zhang, X.D. | 登録日 | 2018-05-02 | 公開日 | 2018-07-04 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structures of Bacterial RNA Polymerase Complexes Reveal the Mechanism of DNA Loading and Transcription Initiation. Mol. Cell, 70, 2018
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6C6S
| CryoEM structure of E.coli RNA polymerase elongation complex bound with RfaH | 分子名称: | DNA (29-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Kang, J.Y, Artsimovitch, I, Landick, R, Darst, S.A. | 登録日 | 2018-01-19 | 公開日 | 2018-07-25 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural Basis for Transcript Elongation Control by NusG Family Universal Regulators. Cell, 173, 2018
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8ABY
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8AC2
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7MKE
| Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR promoter DNA (class 2) | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Saecker, R.M, Darst, S.A, Chen, J. | 登録日 | 2021-04-23 | 公開日 | 2021-09-29 | 最終更新日 | 2021-10-13 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural origins of Escherichia coli RNA polymerase open promoter complex stability. Proc.Natl.Acad.Sci.USA, 118, 2021
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6XDQ
| Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B3 (TTC-B3) containing an mRNA with a 30 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Molodtsov, V, Ebright, R.H, Wang, C, Su, M. | 登録日 | 2020-06-11 | 公開日 | 2020-09-02 | 最終更新日 | 2020-09-23 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural basis of transcription-translation coupling. Science, 369, 2020
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6RI9
| Cryo-EM structure of E. coli RNA polymerase backtracked elongation complex in non-swiveled state | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Abdelkareem, M, Saint-Andre, C, Takacs, M, Papai, G, Crucifix, C, Guo, X, Ortiz, J, Weixlbaumer, A. | 登録日 | 2019-04-23 | 公開日 | 2019-07-03 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural Basis of Transcription: RNA Polymerase Backtracking and Its Reactivation. Mol.Cell, 75, 2019
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6C6U
| CryoEM structure of E.coli RNA polymerase elongation complex bound with NusG | 分子名称: | DNA (29-MER), DNA-DIRECTED RNA POLYMERASE BETA', DNA-directed RNA polymerase subunit alpha, ... | 著者 | Kang, J.Y, Artsimovitch, I, Landick, R, Darst, S.A. | 登録日 | 2018-01-19 | 公開日 | 2018-07-25 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural Basis for Transcript Elongation Control by NusG Family Universal Regulators. Cell, 173, 2018
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6R9G
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