6GFW

Cryo-EM structure of bacterial RNA polymerase-sigma54 holoenzyme initial transcribing complex

Summary for 6GFW

Entry DOI	10.2210/pdb6gfw/pdb
EMDB information	4397
Descriptor	DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... (8 entities in total)
Functional Keywords	transcription initiation, dna opening, transcription bubble, de novo rna synthesis, transcription
Biological source	Escherichia coli K-12 More
Total number of polymer chains	9
Total formula weight	484510.28
Authors	Glyde, R.,Ye, F.Z.,Zhang, X.D. (deposition date: 2018-05-02, release date: 2018-07-04, Last modification date: 2024-05-15)
Primary citation	Glyde, R.,Ye, F.,Jovanovic, M.,Kotta-Loizou, I.,Buck, M.,Zhang, X. Structures of Bacterial RNA Polymerase Complexes Reveal the Mechanism of DNA Loading and Transcription Initiation. Mol. Cell, 70:1111-1120.e3, 2018 Cited by PubMed: 29932903 DOI: 10.1016/j.molcel.2018.05.021 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.7 Å)

Structure validation