6GFW
Cryo-EM structure of bacterial RNA polymerase-sigma54 holoenzyme initial transcribing complex
Summary for 6GFW
Entry DOI | 10.2210/pdb6gfw/pdb |
EMDB information | 4397 |
Descriptor | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... (8 entities in total) |
Functional Keywords | transcription initiation, dna opening, transcription bubble, de novo rna synthesis, transcription |
Biological source | Escherichia coli K-12 More |
Total number of polymer chains | 9 |
Total formula weight | 484510.28 |
Authors | Glyde, R.,Ye, F.Z.,Zhang, X.D. (deposition date: 2018-05-02, release date: 2018-07-04, Last modification date: 2024-05-15) |
Primary citation | Glyde, R.,Ye, F.,Jovanovic, M.,Kotta-Loizou, I.,Buck, M.,Zhang, X. Structures of Bacterial RNA Polymerase Complexes Reveal the Mechanism of DNA Loading and Transcription Initiation. Mol. Cell, 70:1111-1120.e3, 2018 Cited by PubMed: 29932903DOI: 10.1016/j.molcel.2018.05.021 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.7 Å) |
Structure validation
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