7XSZ
 
 | | RNA polymerase II elongation complex transcribing a nucleosome (EC115) | | 分子名称: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | | 著者 | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | | 登録日 | 2022-05-15 | | 公開日 | 2022-09-07 | | 最終更新日 | 2022-10-12 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
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6LA8
 | | 349 bp di-nucleosome harboring cohesive DNA termini assembled with linker histone H1.0 | | 分子名称: | CALCIUM ION, DNA (349-MER), Histone H1.0, ... | | 著者 | Adhireksan, Z, Lee, P.L, Sharma, D, Davey, C.A. | | 登録日 | 2019-11-12 | | 公開日 | 2020-10-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Near-atomic resolution structures of interdigitated nucleosome fibres.
Nat Commun, 11, 2020
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8JCC
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7Y7I
 | | chicken KNL2 in complex with the CENP-A nucleosome | | 分子名称: | Chains: I, Chains: J, Histone H2A type 1-B/E, ... | | 著者 | Ariyoshi, M, Jiang, H, Makino, F, Fukagawa, T. | | 登録日 | 2022-06-22 | | 公開日 | 2022-07-13 | | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | | 主引用文献 | The cryo-EM structure of the CENP-A nucleosome in complex with ggKNL2.
Biorxiv, 2022
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6YOV
 | | OCT4-SOX2-bound nucleosome - SHL+6 | | 分子名称: | DNA (142-MER), Green fluorescent protein,POU domain, class 5, ... | | 著者 | Michael, A.K, Kempf, G, Cavadini, S, Bunker, R.D, Thoma, N.H. | | 登録日 | 2020-04-15 | | 公開日 | 2020-05-06 | | 最終更新日 | 2020-07-08 | | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | | 主引用文献 | Mechanisms of OCT4-SOX2 motif readout on nucleosomes.
Science, 368, 2020
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3W98
 | | Crystal Structure of Human Nucleosome Core Particle lacking H3.1 N-terminal region | | 分子名称: | 146-mer DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Iwasaki, W, Miya, Y, Horikoshi, N, Osakabe, A, Tachiwana, H, Shibata, T, Kagawa, W, Kurumizaka, H. | | 登録日 | 2013-04-01 | | 公開日 | 2013-08-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.42 Å) | | 主引用文献 | Contribution of histone N-terminal tails to the structure and stability of nucleosomes
FEBS Open Bio, 3, 2013
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8JLA
 | | Cryo-EM structure of the human nucleosome lacking N-terminal region of H2A, H2B, H3, and H4 | | 分子名称: | DNA (193-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Oishi, T, Hatazawa, S, Kujirai, T, Kato, J, Kobayashi, Y, Ogasawara, M, Akatsu, M, Takizawa, Y, Kurumizaka, H. | | 登録日 | 2023-06-02 | | 公開日 | 2023-10-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | | 主引用文献 | Contributions of histone tail clipping and acetylation in nucleosome transcription by RNA polymerase II.
Nucleic Acids Res., 51, 2023
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8IEG
 | | Bre1(mRBD-RING)/Rad6-Ub/nucleosome complex | | 分子名称: | DNA (147-MER), E3 ubiquitin-protein ligase BRE1, Histone H2A type 1-B/E, ... | | 著者 | Ai, H, Deng, Z, Pan, M, Liu, L. | | 登録日 | 2023-02-15 | | 公開日 | 2023-09-06 | | 最終更新日 | 2023-09-20 | | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | | 主引用文献 | Mechanistic insights into nucleosomal H2B monoubiquitylation mediated by yeast Bre1-Rad6 and its human homolog RNF20/RNF40-hRAD6A.
Mol.Cell, 83, 2023
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7XD0
 | | cryo-EM structure of H2BK34ub nucleosome | | 分子名称: | DNA (146-MER), Histone H2A, Histone H2B type 1-K, ... | | 著者 | Ai, H.S, Liu, A.J, Lou, Z.Y, Liu, L. | | 登録日 | 2022-03-26 | | 公開日 | 2022-04-20 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | | 主引用文献 | H2B Lys34 Ubiquitination Induces Nucleosome Distortion to Stimulate Dot1L Activity.
Nat.Chem.Biol., 18, 2022
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6T93
 | | Nucleosome with OCT4-SOX2 motif at SHL-6 | | 分子名称: | DNA (153-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Michael, A.K, Kempf, G, Cavadini, S, Bunker, R.D, Thoma, N.H. | | 登録日 | 2019-10-25 | | 公開日 | 2020-05-06 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | | 主引用文献 | Mechanisms of OCT4-SOX2 motif readout on nucleosomes.
Science, 368, 2020
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3AZH
 | | Crystal Structure of Human Nucleosome Core Particle Containing H3K122Q mutation | | 分子名称: | 146-MER DNA, CHLORIDE ION, Histone H2A type 1-B/E, ... | | 著者 | Iwasaki, W, Tachiwana, H, Kawaguchi, K, Shibata, T, Kagawa, W, Kurumizaka, H. | | 登録日 | 2011-05-25 | | 公開日 | 2011-09-21 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.49 Å) | | 主引用文献 | Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains
Biochemistry, 50, 2011
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7NL0
 | | Cryo-EM structure of the Lin28B nucleosome core particle | | 分子名称: | DNA (131-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Roberts, G.A, Ozkan, B, Gachulincova, I, O Dwyer, M.R, Hall-Ponsele, E, Saxena, M, Robinson, P.J, Soufi, A. | | 登録日 | 2021-02-19 | | 公開日 | 2021-08-11 | | 最終更新日 | 2021-09-29 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Dissecting OCT4 defines the role of nucleosome binding in pluripotency.
Nat.Cell Biol., 23, 2021
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7SCZ
 | | Nuc147 bound to multiple BRCTs | | 分子名称: | DNA (147-MER), Histone H2A, Histone H2B type 1-J, ... | | 著者 | Muthurajan, U.M, Rudolph, J. | | 登録日 | 2021-09-29 | | 公開日 | 2022-01-19 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | The BRCT domain of PARP1 binds intact DNA and mediates intrastrand transfer.
Mol.Cell, 81, 2021
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6R94
 | | Cryo-EM structure of NCP_THF2(-3) | | 分子名称: | Histone H2A type 1-B/E, Histone H2B type 1-J, Histone H3.1, ... | | 著者 | Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H. | | 登録日 | 2019-04-02 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | DNA damage detection in nucleosomes involves DNA register shifting.
Nature, 571, 2019
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7V90
 | | Telomeric mononucleosome | | 分子名称: | DNA (145-mer), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | | 著者 | Soman, A. | | 登録日 | 2021-08-24 | | 公開日 | 2022-07-27 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Columnar structure of human telomeric chromatin.
Nature, 609, 2022
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7XVL
 | | Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169an DNA fragment) | | 分子名称: | DNA (169-MER), Histone H1.0, Histone H2A type 1-B/E, ... | | 著者 | Adhireksan, Z, Qiuye, B, Lee, P.L, Sharma, D, Padavattan, S, Davey, C.A. | | 登録日 | 2022-05-24 | | 公開日 | 2023-05-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.506 Å) | | 主引用文献 | Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169an DNA fragment)
To Be Published
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4YM6
 | | Crystal structure of the human nucleosome containing 6-4PP (outside) | | 分子名称: | 145-MER DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Osakabe, A, Tachiwana, H, Kagawa, W, Horikoshi, N, Matsumoto, S, Hasegawa, M, Matsumoto, N, Toga, T, Yamamoto, J, Hanaoka, F, Thoma, N.H, Sugasawa, K, Iwai, S, Kurumizaka, H. | | 登録日 | 2015-03-06 | | 公開日 | 2015-12-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.514 Å) | | 主引用文献 | Structural basis of pyrimidine-pyrimidone (6-4) photoproduct recognition by UV-DDB in the nucleosome
Sci Rep, 5, 2015
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7V99
 | | catalytic core of human telomerase holoenzyme | | 分子名称: | Histone H2A type 1-B/E, Histone H2B type 1-K, Primer DNA, ... | | 著者 | Wan, F, Ding, Y, Yang, L, Wu, Z, Wu, J, Lei, M. | | 登録日 | 2021-08-24 | | 公開日 | 2022-03-30 | | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | | 主引用文献 | Zipper head mechanism of telomere synthesis by human telomerase.
Cell Res., 31, 2021
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8UQE
 | | Crystal structure of RNF168 (RING)-UbcH5c fused to H2A-H2B via a 26-residue linker (RING not modeled in density) | | 分子名称: | E3 ubiquitin-protein ligase RNF168,Ubiquitin-conjugating enzyme E2 D3,Histone H2B type 2-E,Histone H2A type 1-B/E | | 著者 | Hu, Q, Botuyan, M.V, Mer, G. | | 登録日 | 2023-10-23 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.562 Å) | | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
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8JHG
 | | Native SUV420H1 bound to 167-bp nucleosome | | 分子名称: | DNA (160-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | | 著者 | Lin, F, Li, W. | | 登録日 | 2023-05-23 | | 公開日 | 2023-11-22 | | 最終更新日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | | 主引用文献 | Structural basis of nucleosomal H4K20 recognition and methylation by SUV420H1 methyltransferase.
Cell Discov, 9, 2023
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8OSK
 | | Cryo-EM structure of CLOCK-BMAL1 bound to a nucleosomal E-box at position SHL+5.8 (composite map) | | 分子名称: | Basic helix-loop-helix ARNT-like protein 1, Circadian locomoter output cycles protein kaput, DNA (124-MER), ... | | 著者 | Stoos, L, Michael, A.K, Kempf, G, Cavadini, S, Thoma, N.H. | | 登録日 | 2023-04-19 | | 公開日 | 2023-05-24 | | 最終更新日 | 2023-07-26 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Cooperation between bHLH transcription factors and histones for DNA access.
Nature, 619, 2023
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8W9E
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7XSE
 | | RNA polymerase II elongation complex transcribing a nucleosome (EC42) | | 分子名称: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | | 著者 | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | | 登録日 | 2022-05-13 | | 公開日 | 2022-09-07 | | 最終更新日 | 2022-10-12 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
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8SN2
 | | Cryo-EM structure of the human nucleosome core particle in complex with RNF168 and UbcH5c (UbcH5c chemically conjugated to histone H2A) | | 分子名称: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | | 著者 | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | | 登録日 | 2023-04-26 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
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8TXW
 | | Cryo-EM structure of the human nucleosome core particle ubiquitylated at histone H2A K15 in complex with RNF168 (Class 2) | | 分子名称: | DNA (147-MER), E3 ubiquitin-protein ligase RNF168, Histone H2A type 1-B/E, ... | | 著者 | Hu, Q, Botuyan, M.V, Zhao, D, Cui, G, Mer, G. | | 登録日 | 2023-08-24 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Mechanisms of RNF168 nucleosome recognition and ubiquitylation.
Mol.Cell, 84, 2024
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