7NL0

Cryo-EM structure of the Lin28B nucleosome core particle

Summary for 7NL0

• Entry DOI: 10.2210/pdb7nl0/pdb
• EMDB information: 12453
• Descriptor: Histone H3.1, Histone H4, Histone H2A type 1-B/E, ... (6 entities in total)
• Functional Keywords: reprogramming, oct4 binding sites, nucleosome, gene regulation
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 10
• Total formula weight: 209858.79

Authors

Roberts, G.A.,Ozkan, B.,Gachulincova, I.,O Dwyer, M.R.,Hall-Ponsele, E.,Saxena, M.,Robinson, P.J.,Soufi, A. (deposition date: 2021-02-19, release date: 2021-08-11, Last modification date: 2024-07-10)

• Primary citation: Roberts, G.A.,Ozkan, B.,Gachulincova, I.,O'Dwyer, M.R.,Hall-Ponsele, E.,Saxena, M.,Robinson, P.J.,Soufi, A.; Dissecting OCT4 defines the role of nucleosome binding in pluripotency.; Nat.Cell Biol., 23:834-845, 2021; PubMed: 34354236; DOI: 10.1038/s41556-021-00727-5

Experimental method

ELECTRON MICROSCOPY (3.5 Å)