3AZH

Crystal Structure of Human Nucleosome Core Particle Containing H3K122Q mutation

Summary for 3AZH

Related3AFA 3AYW 3AZE 3AZF 3AZG 3AZI 3AZJ 3AZK 3AZL 3AZM 3AZN
DescriptorHistone H3.1, Histone H4, Histone H2A type 1-B/E, ... (7 entities in total)
Functional Keywordshistone-fold, nucleosome, structural protein-dna complex, structural protein/dna
Biological sourceHomo sapiens (human)
Cellular locationNucleus P68431 P62805 P04908 P06899
Total number of polymer chains10
Total molecular weight202994.2
Authors
Iwasaki, W.,Tachiwana, H.,Kawaguchi, K.,Shibata, T.,Kagawa, W.,Kurumizaka, H. (deposition date: 2011-05-25, release date: 2011-09-21, Last modification date: 2012-08-01)
Primary citation
Iwasaki, W.,Tachiwana, H.,Kawaguchi, K.,Shibata, T.,Kagawa, W.,Kurumizaka, H.
Comprehensive Structural Analysis of Mutant Nucleosomes Containing Lysine to Glutamine (KQ) Substitutions in the H3 and H4 Histone-Fold Domains
Biochemistry, 50:7822-7832, 2011
PubMed: 21812398 (PDB entries with the same primary citation)
DOI: 10.1021/bi201021h
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.49 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.266401.2%7.1%0.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution