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PDB: 77 件
5Z3Q
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Crystal Structure of a Soluble Fragment of Poliovirus 2C ATPase (2.55 Angstrom)
分子名称: PHOSPHATE ION, PV-2C, ZINC ION
著者Guan, H, Tian, J, Zhang, C, Qin, B, Cui, S.
登録日2018-01-08
公開日2018-09-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.545 Å)
主引用文献Crystal structure of a soluble fragment of poliovirus 2CATPase
PLoS Pathog., 14, 2018
4NLX
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Poliovirus Polymerase - G289A/C290V Loop Mutant
分子名称: ACETIC ACID, PENTAETHYLENE GLYCOL, RNA-directed RNA polymerase 3D-POL, ...
著者Sholders, A.J, Peersen, O.B.
登録日2013-11-14
公開日2014-01-22
最終更新日2014-03-26
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Distinct conformations of a putative translocation element in poliovirus polymerase.
J.Mol.Biol., 426, 2014
2IM3
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Crystal structure of poliovirus polymerase complexed with UTP and Mn2+
分子名称: ACETIC ACID, MANGANESE (II) ION, SODIUM ION, ...
著者Thompson, A.A, Peersen, O.B.
登録日2006-10-03
公開日2006-12-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Stabilization of Poliovirus Polymerase by NTP Binding and Fingers-Thumb Interactions.
J.Mol.Biol., 366, 2007
2ILY
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Crystal structure of poliovirus polymerase complexed with ATP and Mg2+
分子名称: ACETIC ACID, ADENOSINE-5'-TRIPHOSPHATE, Poliovirus polymerase, ...
著者Thompson, A.A, Peersen, O.B.
登録日2006-10-03
公開日2006-12-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Stabilization of Poliovirus Polymerase by NTP Binding and Fingers-Thumb Interactions.
J.Mol.Biol., 366, 2007
4K4V
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Poliovirus polymerase elongation complex (r5+1_form)
分子名称: DNA/RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*A)-D(P*C)-3'), RNA (5'-R(*AP*AP*GP*UP*CP*UP*CP*CP*AP*GP*GP*UP*CP*UP*CP*UP*CP*UP*CP*GP*UP*CP*GP*AP*AP*A)-3'), RNA-directed RNA polymerase 3D-POL, ...
著者Gong, P, Peersen, O.B.
登録日2013-04-12
公開日2013-05-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts.
Plos One, 8, 2013
4K4W
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Poliovirus polymerase elongation complex (r5+2_form)
分子名称: RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*AP*CP*C)-3'), RNA (5'-R(P*GP*GP*GP*AP*GP*AP*UP*GP*AP*AP*AP*GP*UP*CP*UP*CP*CP*AP*GP*GP*UP*CP*UP*CP*UP*CP*UP*CP*GP*UP*CP*GP*AP*AP*A)-3'), RNA-directed RNA polymerase 3D-POL
著者Gong, P, Peersen, O.B.
登録日2013-04-12
公開日2013-05-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts.
Plos One, 8, 2013
3OL7
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Poliovirus polymerase elongation complex with CTP
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, ISOPROPYL ALCOHOL, ...
著者Gong, P, Peersen, O.B.
登録日2010-08-25
公開日2010-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase.
Proc.Natl.Acad.Sci.USA, 107, 2010
4K4T
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Poliovirus polymerase elongation complex (r4_form)
分子名称: GLYCEROL, RNA (5'-R(*AP*AP*GP*UP*CP*UP*CP*CP*AP*GP*GP*UP*CP*UP*CP*UP*CP*GP*GP*AP*AP*A)-3'), RNA (5'-R(*GP*GP*GP*AP*GP*AP*UP*GP*A)-3'), ...
著者Gong, P, Peersen, O.B.
登録日2013-04-12
公開日2013-05-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts.
Plos One, 8, 2013
1POV
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ROLE AND MECHANISM OF THE MATURATION CLEAVAGE OF VP0 IN POLIOVIRUS ASSEMBLY: STRUCTURE OF THE EMPTY CAPSID ASSEMBLY INTERMEDIATE AT 2.9 ANGSTROMS RESOLUTION
分子名称: MYRISTIC ACID, POLIOVIRUS NATIVE EMPTY CAPSID (TYPE 1), SPHINGOSINE
著者Basavappa, R, Filman, D.J, Hogle, J.M.
登録日1995-08-10
公開日1995-12-07
最終更新日2023-04-19
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Role and mechanism of the maturation cleavage of VP0 in poliovirus assembly: structure of the empty capsid assembly intermediate at 2.9 A resolution.
Protein Sci., 3, 1994
4K4U
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Poliovirus polymerase elongation complex (r5_form)
分子名称: RNA (5'-R(*AP*AP*GP*UP*CP*UP*CP*CP*AP*GP*GP*UP*CP*UP*CP*UP*CP*UP*CP*GP*UP*CP*GP*AP*AP*A)-3'), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*A)-3'), RNA (5'-R(P*GP*GP*GP*GP*GP*AP*GP*AP*UP*GP*A)-3'), ...
著者Gong, P, Peersen, O.B.
登録日2013-04-12
公開日2013-05-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts.
Plos One, 8, 2013
2PLV
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STRUCTURAL FACTORS THAT CONTROL CONFORMATIONAL TRANSITIONS AND SEROTYPE SPECIFICITY IN TYPE 3 POLIOVIRUS
分子名称: HUMAN POLIOVIRUS TYPE 1 (SUBUNIT VP1), HUMAN POLIOVIRUS TYPE 1 (SUBUNIT VP2), HUMAN POLIOVIRUS TYPE 1 (SUBUNIT VP3), ...
著者Filman, D.J, Hogle, J.M.
登録日1989-10-17
公開日1989-10-17
最終更新日2023-04-19
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献Structural factors that control conformational transitions and serotype specificity in type 3 poliovirus
EMBO J., 8, 1989
6P9O
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Poliovirus 135S-like expanded particle in complex with a monoclonal antibody directed against the N-terminal extension of capsid protein VP1
分子名称: VP1, VP2, VP3
著者Hogle, J.M, Filman, D.J, Shah, P.N.M.
登録日2019-06-10
公開日2020-06-10
最終更新日2020-10-21
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Cryo-EM structures reveal two distinct conformational states in a picornavirus cell entry intermediate.
Plos Pathog., 16, 2020
1AR7
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P1/MAHONEY POLIOVIRUS, DOUBLE MUTANT P1095S + H2142Y
分子名称: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
著者Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
登録日1997-08-11
公開日1997-12-03
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997
1AR8
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P1/MAHONEY POLIOVIRUS, MUTANT P1095S
分子名称: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
著者Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
登録日1997-08-11
公開日1997-12-03
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997
1ASJ
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P1/MAHONEY POLIOVIRUS, AT CRYOGENIC TEMPERATURE
分子名称: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
著者Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
登録日1997-08-11
公開日1997-12-03
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997
1AL2
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P1/MAHONEY POLIOVIRUS, SINGLE SITE MUTANT V1160I
分子名称: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
著者Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
登録日1997-06-09
公開日1997-11-19
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997
1AR6
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P1/MAHONEY POLIOVIRUS, DOUBLE MUTANT V1160I +P1095S
分子名称: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
著者Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
登録日1997-08-11
公開日1997-12-03
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997
1AR9
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P1/MAHONEY POLIOVIRUS, SINGLE SITE MUTANT H2142Y
分子名称: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
著者Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
登録日1997-08-11
公開日1997-12-03
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997
1VBD
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POLIOVIRUS (TYPE 1, MAHONEY STRAIN) COMPLEXED WITH R78206
分子名称: (METHYLPYRIDAZINE PIPERIDINE PROPYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 1 MAHONEY
著者Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
登録日1996-01-02
公開日1996-07-11
最終更新日2023-04-19
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
1PO2
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POLIOVIRUS (TYPE 1, MAHONEY) IN COMPLEX WITH R77975, AN INHIBITOR OF VIRAL REPLICATION
分子名称: (METHYLPYRIDAZINE PIPERIDINE ETHYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 1 MAHONEY
著者Hiremath, C.N, Filman, D.J, Grant, R.A, Hogle, J.M.
登録日1997-01-08
公開日1997-12-03
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Ligand-induced conformational changes in poliovirus-antiviral drug complexes.
Acta Crystallogr.,Sect.D, 53, 1997
1PO1
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POLIOVIRUS (TYPE 1, MAHONEY) IN COMPLEX WITH R80633, AN INHIBITOR OF VIRAL REPLICATION
分子名称: (METHYLPYRIDAZINE PIPERIDINE BUTYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 1 MAHONEY
著者Hiremath, C.N, Filman, D.J, Grant, R.A, Hogle, J.M.
登録日1997-01-08
公開日1997-12-03
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Ligand-induced conformational changes in poliovirus-antiviral drug complexes.
Acta Crystallogr.,Sect.D, 53, 1997
4R0E
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BU of 4r0e by Molmil
Crystal Structure of the Poliovirus RNA-Dependent RNA Polymerase Low-Fidelity Mutant 3Dpol H273R
分子名称: RNA-directed RNA polymerase
著者Marcotte, L.L, Gohara, D.W, Filman, D.J, Hogle, J.M.
登録日2014-07-30
公開日2014-11-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Dynamics as a Contributor to Error-prone Replication by an RNA-dependent RNA Polymerase.
J.Biol.Chem., 289, 2014
2IJF
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Crystal Structure of the Poliovirus RNA-Dependent RNA Polymerase Fidelity Mutant 3Dpol G64S
分子名称: RNA-directed RNA polymerase
著者Marcotte, L.L, Gohara, D.G, Filman, D.J, Hogle, J.M.
登録日2006-09-29
公開日2007-02-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of poliovirus 3CD: virally-encoded protease and precursor to the RNA-dependent RNA polymerase.
J.Virol., 81, 2007
1FPT
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THREE-DIMENSIONAL STRUCTURE OF THE COMPLEX BETWEEN THE FAB FRAGMENT OF AN NEUTRALIZING ANTIBODY FOR TYPE 1 POLIOVIRUS AND ITS VIRAL EPITOPE
分子名称: FAB FRAGMENT OF AN NEUTRALIZING ANTIBODY FOR TYPE 1 POLIOVIRUS, IGG2A-KAPPA C3 FAB (HEAVY CHAIN), IGG2A-KAPPA C3 FAB (LIGHT CHAIN)
著者Wien, M.W, Hogle, J.M.
登録日1995-01-26
公開日1995-03-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the complex between the Fab fragment of a neutralizing antibody for type 1 poliovirus and its viral epitope.
Nat.Struct.Biol., 2, 1995
8E8L
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9H2 Fab-poliovirus 1 complex
分子名称: 9H2 Fab heavy chain, 9H2 Fab light chain, Capsid protein VP1, ...
著者Charnesky, A.J.
登録日2022-08-25
公開日2023-06-21
最終更新日2023-10-18
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献A human monoclonal antibody binds within the poliovirus receptor-binding site to neutralize all three serotypes.
Nat Commun, 14, 2023

223532

件を2024-08-07に公開中

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